ChemicalBook > CAS DataBase List > Methyl 2-methoxy-5-sulfamoylbenzoate

Methyl 2-methoxy-5-sulfamoylbenzoate

Product Name
Methyl 2-methoxy-5-sulfamoylbenzoate
CAS No.
33045-52-2
Chemical Name
Methyl 2-methoxy-5-sulfamoylbenzoate
Synonyms
Sulpride Impurity B;Methyl2-Methoxy-5-S;Sulpiride EP Impurity B;Sulpiride Impurity B(EP);Sulpiride impurity B CRS;2-Methoxy-5-sulfamoylbenzoic;methyl 5-sulphamoyl-o-anisate;Sulpiride impurity B (S2192000);Methyl[5-Amino Sulfonyl-2-Methoxy];Methyl 2-Methoxy-5-sulphamoylbenzoa
CBNumber
CB9455786
Molecular Formula
C9H11NO5S
Formula Weight
245.25
MOL File
33045-52-2.mol
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Methyl 2-methoxy-5-sulfamoylbenzoate Property

Melting point:
175-177 °C (lit.)
Boiling point:
439.8±55.0 °C(Predicted)
Density 
1.360±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
9.94±0.60(Predicted)
color 
White to Off-White
InChI
InChI=1S/C9H11NO5S/c1-14-8-4-3-6(16(10,12)13)5-7(8)9(11)15-2/h3-5H,1-2H3,(H2,10,12,13)
InChIKey
MKDYDRQLKPGNNU-UHFFFAOYSA-N
SMILES
C(OC)(=O)C1=CC(S(N)(=O)=O)=CC=C1OC
LogP
0.36
CAS DataBase Reference
33045-52-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2922500090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S2192000
Product name
Sulpiride impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
10 mg
Price
$156
Updated
2025/07/31
Sigma-Aldrich
Product number
522279
Product name
Methyl 2-methoxy-5-sulfamoylbenzoate
Purity
98%
Packaging
25g
Price
$158
Updated
2025/07/31
Sigma-Aldrich
Product number
S2192000
Product name
Sulpiride impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
s2192000
Price
$153
Updated
2024/03/01
TCI Chemical
Product number
M1942
Product name
Methyl 5-(Aminosulfonyl)-2-methoxybenzoate
Purity
>98.0%(HPLC)
Packaging
25g
Price
$80
Updated
2021/12/16
AK Scientific
Product number
J11196
Product name
Sulpiride impurity B
Packaging
100mg
Price
$57.2
Updated
2021/12/16
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Methyl 2-methoxy-5-sulfamoylbenzoate Chemical Properties,Usage,Production

Uses

Methyl 2-methoxy-5-sulfamoylbenzoate is a reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypog lycemic agents.

Preparation

Methyl 2-methoxy-5-aminosulfonyl benzoate is an important intermediate for the synthesis of sulpiride, which is the main drug for treatment of psychiatric disorders such as schizophrenia and depression. The synthetic route of methyl 2-methoxy-5-aminosulfonyl benzoate is composed mainly of etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification, which prepared successfully with the help of salicylic acid and methyl salicylate as precursor. The raw materials of the synthetic route are salicylic acid and methyl salicylate, which was synthesized by etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification.

synthetic procedure of Methyl 2-Methoxy-5-Aminosulfonyl Benzoate

General Description

Methyl 2-methoxy-5-sulfamoylbenzoate is also referred to as 2-methoxy-5-sulfamoyl methyl benzoate or methyl 5-(aminosulphonyl)-2-methoxybenzoate.

Methyl 2-methoxy-5-sulfamoylbenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 2-methoxy-5-sulfamoylbenzoate Suppliers

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View Lastest Price from Methyl 2-methoxy-5-sulfamoylbenzoate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-19
Hebei Fengqiang Trading Co., LTD
Product
Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-09-07
Career Henan Chemical Co
Product
Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2
Price
US $7.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-21

33045-52-2, Methyl 2-methoxy-5-sulfamoylbenzoateRelated Search:

Methylparaben o-Anisaldehyde 4-Methoxybenzoic acid Kresoxim-methyl Methyl methoxyacetate Methyl benzoate (Trifluoromethoxy)benzene o-Anisidine Methyl 2-iodobenzoate Bensulfuron methyl Anisole Guaiacol Methyl acrylate Methyl acetate Thiophanate-methyl Methyl Methyl bromide Ethyl 2-methoxy-5-sulfamoylbenzoate

  • 5-Aminosulfonyl-2-Methoxy-Benzoic Acid Methyl Ester
  • 2-Methoxy-5-Aminosulfonyl Benzoic Acid Methyl Ester Methyl 2-Methoxy-5-Aminosulfonyl Benzoate
  • Methyl 5-(aminosulphonyl)-2-methoxybenzoate
  • METHYL 2-METHOXY-5-SULFAMOYLBENZOATE, 98 %
  • 2-Methoxy-5-sulfamoylbenzoic
  • 2-METHOXY-5-SULFAMIDE METHYL BENZOATE
  • 2-methoxy-5-sulfamoyl methyl benzoate
  • 4-Methoxy-3-(methoxycarbonyl)benzenesulfonamide
  • 2-METHOXY-5-SULFAMOYLBENZOIC ACID METHYL ESTER (33045-52-2)
  • Methyl 2-methoxy-5-sulfamoylbenzoate (CAS NO 33045-52-2)
  • Sulpiride EP Impurity B
  • Sulpride Impurity B
  • Sulpiride Impurity 2（Sulpiride EP Impurity B）
  • Methyl2-Methoxy-5-S
  • Methyl[5-Amino Sulfonyl-2-Methoxy]
  • 5-(Aminosulfonyl)-2-methoxybenzoic Acid Methyl Ester Methyl 2-Methoxy-5-sulfamoylbenzoate 2-Methoxy-5-sulfamoylbenzoic Acid Methyl Ester
  • METHYL-2-METHOXY-5-(AMINOSULPHONYL) BENZOATE(LEVOSULPIRIDE INTERMEDIATES)
  • Sulpiride Impurity B(EP)
  • Benzoic acid,5-(aMinosulfonyl)-2-Methoxy-, Methyl ester
  • 2-METHOXY-5-AMINO SULFONYL BENZOIC ACID METHYL ESTER
  • 2-METHOXY-5-AMINOSULFONYL-METHYL BENZOATE
  • 2-METHOXY-5-SULFAMOYLBENZOIC ACID METHYL ESTER
  • METHYL 2-METHOXY-5-AMINOSULFONYLBENZOATE
  • METHYL 2-METHOXY-5-SULFAMOYLBENZOATE
  • METHYL[5-AMINO SULFONYL-2-METHOXY] BENZOATE
  • methyl 5-sulphamoyl-o-anisate
  • 1-(5,5,7,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethanone
  • Methyl5-(Aminosulfonyl)-2-methoxybenzoate&gt
  • Methyl 2-Methoxy-5-sulphamoylbenzoa
  • Sulpiride impurity B CRS
  • Methyl 2-methoxy-5-sulfamoylbenzoate ISO 9001：2015 REACH
  • Sulpiride impurity B (S2192000)
  • Methyl 2-methoxy-5-sulfamoylbenzoatev
  • Methyl 5-(Aminosulfonyl)-2-methoxybenzoate, ≥ 98.0%
  • Methyl 2-Methoxy-5-sulphamoylbenzoate
  • Methyl 2-Methoxy-5-Sulfamoyibenzaate
  • 2-Methoxy-5-Aminosulfonyl sulfamoylbenzoate Methyl Ester 2--5-
  • 33045-52-2
  • 22045-52-2
  • CH3OC6H3SO2NH2CO2CH3
  • Building Blocks
  • Organic Building Blocks
  • Sulfonamides/Sulfinamides
  • Sulfur Compounds
  • FINE Chemical & INTERMEDIATES
  • Organic Building Blocks
  • Sulfonamides/Sulfinamides
  • Sulfur Compounds