Methyl 2-methoxy-5-sulfamoylbenzoate

Product Name: Methyl 2-methoxy-5-sulfamoylbenzoate
CAS No.: 33045-52-2
Chemical Name: Methyl 2-methoxy-5-sulfamoylbenzoate
Synonyms: Sulpride Impurity B;Methyl2-Methoxy-5-S;Sulpiride EP Impurity B;Sulpiride Impurity B(EP);Sulpiride impurity B CRS;2-Methoxy-5-sulfamoylbenzoic;methyl 5-sulphamoyl-o-anisate;Sulpiride impurity B (S2192000);Methyl[5-Amino Sulfonyl-2-Methoxy];Methyl 2-Methoxy-5-sulphamoylbenzoa
CBNumber: CB9455786
Molecular Formula: C9H11NO5S
Formula Weight: 245.25
MOL File: 33045-52-2.mol

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Methyl 2-methoxy-5-sulfamoylbenzoate Property

Melting point:: 175-177 °C (lit.)
Boiling point:: 439.8±55.0 °C(Predicted)
Density: 1.360±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 9.94±0.60(Predicted)
color: White to Off-White
InChI: InChI=1S/C9H11NO5S/c1-14-8-4-3-6(16(10,12)13)5-7(8)9(11)15-2/h3-5H,1-2H3,(H2,10,12,13)
InChIKey: MKDYDRQLKPGNNU-UHFFFAOYSA-N
SMILES: C(OC)(=O)C1=CC(S(N)(=O)=O)=CC=C1OC
LogP: 0.36
CAS DataBase Reference: 33045-52-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
WGK Germany: 3
Hazard Note: Irritant
HS Code: 2922500090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S2192000
Product name: Sulpiride impurity B
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 10 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: 522279
Product name: Methyl 2-methoxy-5-sulfamoylbenzoate
Purity: 98%
Packaging: 25g
Price: $158
Updated: 2025/07/31

Sigma-Aldrich

Product number: S2192000
Product name: Sulpiride impurity B
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: s2192000
Price: $153
Updated: 2024/03/01

TCI Chemical

Product number: M1942
Product name: Methyl 5-(Aminosulfonyl)-2-methoxybenzoate
Purity: >98.0%(HPLC)
Packaging: 25g
Price: $80
Updated: 2021/12/16

AK Scientific

Product number: J11196
Product name: Sulpiride impurity B
Packaging: 100mg
Price: $57.2
Updated: 2021/12/16

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Methyl 2-methoxy-5-sulfamoylbenzoate Chemical Properties,Usage,Production

Uses

Methyl 2-methoxy-5-sulfamoylbenzoate is a reactant used in the preparation of many pharmaceutical compounds used as anticoagulants, HCV NS5B polymerase inhibitors, therapeutic drugs for treatment of neurodegenerative diseases and oral hypog lycemic agents.

Preparation

Methyl 2-methoxy-5-aminosulfonyl benzoate is an important intermediate for the synthesis of sulpiride, which is the main drug for treatment of psychiatric disorders such as schizophrenia and depression. The synthetic route of methyl 2-methoxy-5-aminosulfonyl benzoate is composed mainly of etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification, which prepared successfully with the help of salicylic acid and methyl salicylate as precursor. The raw materials of the synthetic route are salicylic acid and methyl salicylate, which was synthesized by etherification (phenol hydroxyl), sulfonyl chloride, amination and esterification.

synthetic procedure of Methyl 2-Methoxy-5-Aminosulfonyl Benzoate

General Description

Methyl 2-methoxy-5-sulfamoylbenzoate is also referred to as 2-methoxy-5-sulfamoyl methyl benzoate or methyl 5-(aminosulphonyl)-2-methoxybenzoate.

Methyl 2-methoxy-5-sulfamoylbenzoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl 2-methoxy-5-sulfamoylbenzoate Suppliers

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View Lastest Price from Methyl 2-methoxy-5-sulfamoylbenzoate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-19

Hebei Fengqiang Trading Co., LTD

Product: Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2
Price: US $100.00/bag
Min. Order: 1bag
Purity: 99
Supply Ability: 5000
Release date: 2023-09-07

Career Henan Chemical Co

Product: Methyl 2-methoxy-5-sulfamoylbenzoate 33045-52-2
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-21

33045-52-2, Methyl 2-methoxy-5-sulfamoylbenzoateRelated Search:

Methylparaben o-Anisaldehyde 4-Methoxybenzoic acid Kresoxim-methyl Methyl methoxyacetate Methyl benzoate (Trifluoromethoxy)benzene o-Anisidine Methyl 2-iodobenzoate Bensulfuron methyl Anisole Guaiacol Methyl acrylate Methyl acetate Thiophanate-methyl Methyl Methyl bromide Ethyl 2-methoxy-5-sulfamoylbenzoate

5-Aminosulfonyl-2-Methoxy-Benzoic Acid Methyl Ester

2-Methoxy-5-Aminosulfonyl Benzoic Acid Methyl Ester Methyl 2-Methoxy-5-Aminosulfonyl Benzoate

Methyl 5-(aminosulphonyl)-2-methoxybenzoate

METHYL 2-METHOXY-5-SULFAMOYLBENZOATE, 98 %

2-Methoxy-5-sulfamoylbenzoic

2-METHOXY-5-SULFAMIDE METHYL BENZOATE

2-methoxy-5-sulfamoyl methyl benzoate

4-Methoxy-3-(methoxycarbonyl)benzenesulfonamide

2-METHOXY-5-SULFAMOYLBENZOIC ACID METHYL ESTER (33045-52-2)

Methyl 2-methoxy-5-sulfamoylbenzoate (CAS NO 33045-52-2)

Sulpiride EP Impurity B

Sulpride Impurity B

Sulpiride Impurity 2（Sulpiride EP Impurity B）

Methyl2-Methoxy-5-S

Methyl[5-Amino Sulfonyl-2-Methoxy]

5-(Aminosulfonyl)-2-methoxybenzoic Acid Methyl Ester Methyl 2-Methoxy-5-sulfamoylbenzoate 2-Methoxy-5-sulfamoylbenzoic Acid Methyl Ester

METHYL-2-METHOXY-5-(AMINOSULPHONYL) BENZOATE(LEVOSULPIRIDE INTERMEDIATES)

Sulpiride Impurity B(EP)

Benzoic acid,5-(aMinosulfonyl)-2-Methoxy-, Methyl ester

2-METHOXY-5-AMINO SULFONYL BENZOIC ACID METHYL ESTER

2-METHOXY-5-AMINOSULFONYL-METHYL BENZOATE

2-METHOXY-5-SULFAMOYLBENZOIC ACID METHYL ESTER

METHYL 2-METHOXY-5-AMINOSULFONYLBENZOATE

METHYL 2-METHOXY-5-SULFAMOYLBENZOATE

METHYL[5-AMINO SULFONYL-2-METHOXY] BENZOATE

methyl 5-sulphamoyl-o-anisate

1-(5,5,7,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethanone

Methyl5-(Aminosulfonyl)-2-methoxybenzoate&gt

Methyl 2-Methoxy-5-sulphamoylbenzoa

Sulpiride impurity B CRS

Methyl 2-methoxy-5-sulfamoylbenzoate ISO 9001：2015 REACH

Sulpiride impurity B (S2192000)

Methyl 2-methoxy-5-sulfamoylbenzoatev

Methyl 5-(Aminosulfonyl)-2-methoxybenzoate, ≥ 98.0%

Methyl 2-Methoxy-5-sulphamoylbenzoate

Methyl 2-Methoxy-5-Sulfamoyibenzaate

2-Methoxy-5-Aminosulfonyl sulfamoylbenzoate Methyl Ester 2--5-

33045-52-2

22045-52-2

CH3OC6H3SO2NH2CO2CH3

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Organic Building Blocks

Sulfonamides/Sulfinamides

Sulfur Compounds