2'-Deoxyuridine 5'-monophosphate disodium salt
- Product Name
- 2'-Deoxyuridine 5'-monophosphate disodium salt
- CAS No.
- 42155-08-8
- Chemical Name
- 2'-Deoxyuridine 5'-monophosphate disodium salt
- Synonyms
- dump;DUMP 2NA;2'-dUMP?2Na;dUMP·（Na·salt）;D-UMP DISODIUM SALT;Diquafosol Impurity 22;Diquafosol Impurity 30;dUMP 100mM Sodium Solution;2'-Deoxyuridine 5'-monophosphate;2'-Deoxy-5'-uridylic acid disodium salt
- CBNumber
- CB9482517
- Molecular Formula
- C9H14N2NaO8P
- Formula Weight
- 332.18
- MOL File
- 42155-08-8.mol
2'-Deoxyuridine 5'-monophosphate disodium salt Property
- storage temp.
- -20°C
- solubility
- PBS (pH 7.2): 1 mg/ml
- form
- Powder
- color
- White to Off-white
- Water Solubility
- Soluble in water.
- CAS DataBase Reference
- 42155-08-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D3876
- Product name
- 2′-Deoxyuridine 5′-monophosphate disodium salt
- Purity
- Sigma Grade
- Packaging
- 100mg
- Price
- $256
- Updated
- 2024/03/01
- Product number
- D3876
- Product name
- 2′-Deoxyuridine 5′-monophosphate disodium salt
- Purity
- Sigma Grade
- Packaging
- 1g
- Price
- $1490
- Updated
- 2024/03/01
- Product number
- J64627
- Product name
- 2'-Deoxyuridine-5'-monophosphate disodium salt, 99%
- Packaging
- 250mg
- Price
- $110
- Updated
- 2024/03/01
- Product number
- J64627
- Product name
- 2'-Deoxyuridine-5'-monophosphate disodium salt, 99%
- Packaging
- 1g
- Price
- $237
- Updated
- 2024/03/01
- Product number
- D3876
- Product name
- 2′-Deoxyuridine 5′-monophosphate disodium salt
- Purity
- Sigma Grade
- Packaging
- 250mg
- Price
- $487
- Updated
- 2024/03/01
2'-Deoxyuridine 5'-monophosphate disodium salt Chemical Properties,Usage,Production
Description
2'-Deoxyuridine 5'-monophosphate disodium salt is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate. 2'-Deoxyuridine 5'-monophosphate disodium salt has been shown to be effective in treating squamous cell cancer and hyperproliferative diseases such as chronic myelogenous leukemia. 2'-Deoxyuridine 5'-monophosphate disodium salt is also used as an antiviral agent against HIV, herpes simplex virus, and varicella zoster virus.
Uses
2?-Deoxyuridine 5?-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) (EC 2.1.1.45) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications.
General Description
2′-Deoxyuridine 5′-monophosphate disodium salt (dUMP) is a substrate for thymidylate synthase and is converted to deoxythymidine monophosphate (dTMP).
Biochem/physiol Actions
2′-Deoxyuridine 5′-monophosphate disodium salt (dUMP) conversion to pyrimidine is inhibited by methotrexate. The inhibition of dUMP to deoxythymidine monophosphate (dTMP) at the methylation step is a key in controlling bacterial and eukaryotic cell growth.
2'-Deoxyuridine 5'-monophosphate disodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2'-Deoxyuridine 5'-monophosphate disodium salt manufacturers
- Product
- 2'-Deoxyuridine 5'-monophosphate disodium salt (dUMP-Na2) 42155-08-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.10000000149011612kg
- Purity
- ≥99.0%
- Supply Ability
- 500 kg
- Release date
- 2024-02-07
- Product
- 2'-Deoxyuridine 5'-monophosphate disodium salt 42155-08-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-26
- Product
- 2'-Deoxyuridine 5'-monophosphate disodium salt 42155-08-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2020-05-14