2'-Deoxyuridine 5'-monophosphate disodium salt

Product Name: 2'-Deoxyuridine 5'-monophosphate disodium salt
CAS No.: 42155-08-8
Chemical Name: 2'-Deoxyuridine 5'-monophosphate disodium salt
Synonyms: dump;DUMP 2NA;2'-dUMP?2Na;dUMP·（Na·salt）;D-UMP DISODIUM SALT;Diquafosol Impurity 22;Diquafosol Impurity 30;dUMP 100mM Sodium Solution;2'-Deoxyuridine 5'-monophosphate;2'-Deoxy-5'-uridylic acid disodium salt
CBNumber: CB9482517
Molecular Formula: C9H14N2NaO8P
Formula Weight: 332.18
MOL File: 42155-08-8.mol

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2'-Deoxyuridine 5'-monophosphate disodium salt Property

storage temp.: -20°C
solubility: PBS (pH 7.2): 1 mg/ml
form: Powder
color: White to Off-white
Water Solubility: Soluble in water.
CAS DataBase Reference: 42155-08-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38-20/21/22
Safety Statements: 26-36-37/39
WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D3876
Product name: 2′-Deoxyuridine 5′-monophosphate disodium salt
Purity: Sigma Grade
Packaging: 100mg
Price: $256
Updated: 2024/03/01

Sigma-Aldrich

Product number: D3876
Product name: 2′-Deoxyuridine 5′-monophosphate disodium salt
Purity: Sigma Grade
Packaging: 1g
Price: $1490
Updated: 2024/03/01

Alfa Aesar

Product number: J64627
Product name: 2'-Deoxyuridine-5'-monophosphate disodium salt, 99%
Packaging: 250mg
Price: $110
Updated: 2024/03/01

Alfa Aesar

Product number: J64627
Product name: 2'-Deoxyuridine-5'-monophosphate disodium salt, 99%
Packaging: 1g
Price: $237
Updated: 2024/03/01

Sigma-Aldrich

Product number: D3876
Product name: 2′-Deoxyuridine 5′-monophosphate disodium salt
Purity: Sigma Grade
Packaging: 250mg
Price: $487
Updated: 2024/03/01

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2'-Deoxyuridine 5'-monophosphate disodium salt Chemical Properties,Usage,Production

Description

2'-Deoxyuridine 5'-monophosphate disodium salt is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate. 2'-Deoxyuridine 5'-monophosphate disodium salt has been shown to be effective in treating squamous cell cancer and hyperproliferative diseases such as chronic myelogenous leukemia. 2'-Deoxyuridine 5'-monophosphate disodium salt is also used as an antiviral agent against HIV, herpes simplex virus, and varicella zoster virus.

Uses

2?-Deoxyuridine 5?-monophosphate (dUMP) is used by the enzyme thymidylate synthetase (TS) (EC 2.1.1.45) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in potential chemotherapy applications.

General Description

2′-Deoxyuridine 5′-monophosphate disodium salt (dUMP) is a substrate for thymidylate synthase and is converted to deoxythymidine monophosphate (dTMP).

Biochem/physiol Actions

2′-Deoxyuridine 5′-monophosphate disodium salt (dUMP) conversion to pyrimidine is inhibited by methotrexate. The inhibition of dUMP to deoxythymidine monophosphate (dTMP) at the methylation step is a key in controlling bacterial and eukaryotic cell growth.

2'-Deoxyuridine 5'-monophosphate disodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-Deoxyuridine 5'-monophosphate disodium salt Suppliers

China 155 Germany 1 India 5 Switzerland 1 The Netherlands 1 United Kingdom 5 United States 21 Global 189

Brunschwig chemie

Tel: --
Fax: --
Email: brunschwig@brunschwig.nl
Country: The Netherlands
ProdList: 4996
Advantage: 67

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View Lastest Price from 2'-Deoxyuridine 5'-monophosphate disodium salt manufacturers

Hangzhou Meiya Pharmaceutical Co Ltd

Product: 2'-Deoxyuridine 5'-monophosphate disodium salt (dUMP-Na2) 42155-08-8
Price: US $0.00-0.00/kg
Min. Order: 0.10000000149011612kg
Purity: ≥99.0%
Supply Ability: 500 kg
Release date: 2024-02-07

Henan Aochuang Chemical Co.,Ltd.

Product: 2'-Deoxyuridine 5'-monophosphate disodium salt 42155-08-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Shaanxi Dideu Medichem Co. Ltd

Product: 2'-Deoxyuridine 5'-monophosphate disodium salt 42155-08-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-05-14

42155-08-8, 2'-Deoxyuridine 5'-monophosphate disodium saltRelated Search:

Thymidine-5'-monophosphate disodium salt Sodium Phosphate, Dibasic Pamidronate disodium salt Ethylenediaminetetraacetic acid disodium salt Broxuridine Floxuridine Clodronate disodium Uridine 2'-Deoxyuridine Sodium Monofluorophosphate Disodium 5'-dGMP 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Uridine 5′-monophosphate disodium salt 5-BROMO-2''-DEOXYURIDINE-5''-MONOPHOSPHATE DISODIUM SALT URIDYLIC ACID Uracil THYMIDINE 5'-MONOPHOSPHATE, [2-14C] DISODIUM SALT [5',5''-2H2]URIDINE 5'-MONOPHOSPHATE DISODIUM SALT

dump

2''-Deoxyuridine-5''-monophosphoric acid disodium salt

2'-deoxyuridine 5'-monophosphate*disodium sigma G

5'-Uridylic acid, 2'-deoxy-, disodium salt

2'-Deoxyuridine-5'-monophosphate,sodiumsalt

2'-DEOXYURIDINE 5'-MONOPHOSPHATEDISODIUM SIGMA GRA

2''-DEOXYURIDINE 5''-MONOPHOSPHATE DISODIUM SALT (DUMP-NA2)

2'-Deoxy-5'-uridylic acid disodium salt

2'-Deoxyuridine 5'-(phosphoric acid disodium) salt

Sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl phosphate

2'-DEOXYURIDINE 5'-MONOPHOSPHATE DISODIUM SALT

dUMP, 2'-Deoxyuridine-5'-Monophosphate, disodiuM salt

DUMP 2NA

D-UMP DISODIUM SALT

2'-dUMP?2Na

dUMP·（Na·salt）

2′-Deoxyuridine5′-mono-phos-phatedisodiumsal

2'-Deoxyuridine 5'-monophosphate (disodium)

Diquafosol Impurity 22

[(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl phosphate

[(2R,3S,5R)-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate

2`-Deoxyuridine-5`-Monophosphate Disodium Salt (dUMP-Na2) extrapure, 98%

2′-Deoxyuridine-5′-monophosphate disodium salt [dUMP·(Na·salt)

Deoxyuridine 5′-monophosphate (sodium salt)

Diquafosol Impurity 30

Disodium 2'-deoxy-5'-O-phosphonatouridine

dUMP 100mM Sodium Solution

2'-Deoxyuridine 5'-monophosphate

2'-Deoxyuridine 5'-monophosphate disodium salt

Disodium 2'-deoxy-5'-O-phosphonatouridine

2'-Deoxyuridine 5'-monophosphate (disodium)

2'-deoxyuridine 5'-monophosphate*disodium sigma G

42155-08-8

C9H11N2Na2O8P

C9H11N2O8PNa2

Metabolites and Cofactors on the Metabolic Pathways Chart

Metabolic Pathways

Nucleotide

Metabolomics

BioChemical

Nucleotide