Uses
ChemicalBook > CAS DataBase List > 2,5-Dichloropyridine

2,5-Dichloropyridine

Uses
Product Name
2,5-Dichloropyridine
CAS No.
16110-09-1
Chemical Name
2,5-Dichloropyridine
Synonyms
Dichloropyridine;4-Aminophenylacetamide;2,5- twochlorine pyridine;5-Dichloropyridine;2,5-Chloro pyridine;2,5-DICHLORPYRIDINE;2,5-dichloro-pyridin;2,5-DICHLOROPYRIDINE;2,5-Dichiloropyridine;Pyridine, 2,5-dichloro-
CBNumber
CB9487592
Molecular Formula
C5H3Cl2N
Formula Weight
147.99
MOL File
16110-09-1.mol
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2,5-Dichloropyridine Property

Melting point:
59-62 °C (lit.)
Boiling point:
190-191 °C
Density 
1.5159 (rough estimate)
refractive index 
1.5500 (estimate)
Flash point:
112 °C
storage temp. 
Inert atmosphere,Room Temperature
pka
-2.25±0.10(Predicted)
form 
Crystalline Solid
color 
White to slightly yellow
Water Solubility 
insoluble
BRN 
108886
CAS DataBase Reference
16110-09-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-37/39-36
RIDADR 
UN2811
WGK Germany 
3
RTECS 
US8225000
Hazard Note 
Harmful
HazardClass 
IRRITANT
HazardClass 
6.1
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
193763
Product name
2,5-Dichloropyridine
Purity
98%
Packaging
10g
Price
$78.4
Updated
2024/03/01
Sigma-Aldrich
Product number
193763
Product name
2,5-Dichloropyridine
Purity
98%
Packaging
50g
Price
$129
Updated
2023/06/20
TCI Chemical
Product number
D1607
Product name
2,5-Dichloropyridine
Purity
>99.0%(GC)
Packaging
5g
Price
$47
Updated
2024/03/01
TCI Chemical
Product number
D1607
Product name
2,5-Dichloropyridine
Purity
>99.0%(GC)
Packaging
25g
Price
$115
Updated
2024/03/01
Alfa Aesar
Product number
A15442
Product name
2,5-Dichloropyridine, 98%
Packaging
25g
Price
$99.65
Updated
2024/03/01
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2,5-Dichloropyridine Chemical Properties,Usage,Production

Uses

2,5-Dichloropyridine is a reagent used in chemical synthesis. It has been used to synthesize 4-benzodiazepine-2,5 diones as Hdm2 antagonists and inhibitors of ERK protein kinase.

Chemical Properties

white to slightly yellow crystalline solid

Uses

2,5-Dichloropyridine was used in the synthesis of 6-halo-pyridin-3-yl boronic acids and esters. It undergoes cross-coupling reaction with arylboronic acids in the presence of [1,4-bis-(diphenylphosphine)butane]palladium (II) dichloride as catalyst.

Synthesis Reference(s)

Synthetic Communications, 20, p. 2971, 1990 DOI: 10.1080/00397919008051514

General Description

2,5-Dichloropyridine undergoes cross-coupling reaction with arylboronic acids in the presence of [1,4-bis-(diphenylphosphine)butane]palladium (II) dichloride as catalyst.

2,5-Dichloropyridine Preparation Products And Raw materials

Raw materials

Sodium sulfate Sodium chloride 3-Chloropyridine 3-Chloroperoxybenzoic acid Trimethylamine Benzenesulfonyl chloride Dichloromethane Sulfuric acid

Preparation Products

2,5-Dichloroisonicotinic acid 2,5-DICHLORO-4-FORMYLPYRIDINE
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View Lastest Price from 2,5-Dichloropyridine manufacturers

Shanghai Yongzeng Technology Co.,Ltd
Product
2,5-Dichloropyridine 16110-09-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
100kgs
Release date
2024-09-04
Hebei Weibang Biotechnology Co., Ltd
Product
2,5-Dichloropyridine 16110-09-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Hebei Yanxi Chemical Co., Ltd.
Product
2,5-Dichloropyridine 16110-09-1
Price
US $30.00-5.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-28

16110-09-1, 2,5-DichloropyridineRelated Search:

5-Amino-2-methylpyridine 2-Chloro-5-chloromethylpyridine 2-(Hydroxymethyl)pyridine 2,6-Lutidine 1,2-Dichloroethane 2,5-Dimethylpyridine 2,3-DICHLOROPYRIDINE Methyl 2,3,5,6-tetrachloro-4-pyridyl sulfone Triclopyr Picloram Chlorpyrifos 2,3,5,6-Tetrachloropyridine 2,6-Dichloropyridine Dichloropyridine,98% 2,3,5,6-Tetrachloropyridine-4-thiol Pentachloropyridine 2,3,5-Trichloropyridine Clopyralid

  • 2,5-Dichloropyridine, 98% 5GR
  • 2,5- twochlorine pyridine
  • 2,5-Dichiloropyridine
  • 2,5-Chloro pyridine
  • 2,5-dichloro-pyridin
  • 2,5-DICHLORPYRIDINE
  • 2,5-Dichloropyridine97%
  • Dichloropyridine
  • 4-Aminophenylacetamide
  • 2,5-DICHLOROPYRIDINE 2,5-DICHLOROPYRIDINE
  • Pyridine, 2,5-dichloro-
  • 2,5-Dichloropyridine,98%
  • 2,5-dibrochloropyridine
  • 5-Dichloropyridine
  • 2,5-DICHLOROPYRIDINE
  • 2,5-Dichloropyridine&gt
  • 2,5-Dichloropyridine ISO 9001：2015 REACH
  • 16110-09-1
  • 1611-09-1
  • 16110-09-01
  • 240-278-2
  • HETERO CHLORIDE
  • Building Blocks
  • Chloropyridines
  • Halopyridines
  • Pyridines
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Chlorinated heterocyclic series
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Halides
  • Pyridines
  • Chloropyridines
  • Halopyridines
  • Boronic Acid
  • C5Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridine
  • pyridine derivative
  • Building Blocks
  • C5
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • alkyl chloride
  • bc0001