6-Azaindole
- Product Name
- 6-Azaindole
- CAS No.
- 271-29-4
- Chemical Name
- 6-Azaindole
- Synonyms
- 1H-Pyrrolo[2,3-c]pyridine;6-Azaindol;6-Azaindole;6-Aza-1H-indole;6-Azaindole, 98+%;Harmyrine 1,6-Diazaindene;1H-PYRROLO[2,3-C]PYRIDINE 6-AZAINDOLE;6-Azaindole,1H-pyrrolo[2,3-c]pyridine;1H-Pyrrolo[2,3-c]pyridine;1H-Pyrrolo[2,3-c]pyridine (6CI, 7CI, 8CI, 9CI, ACI)
- CBNumber
- CB9677678
- Molecular Formula
- C7H6N2
- Formula Weight
- 118.14
- MOL File
- 271-29-4.mol
6-Azaindole Property
- Melting point:
- 136-137°C
- Boiling point:
- 295.8±13.0 °C(Predicted)
- Density
- 1.242±0.06 g/cm3(Predicted)
- RTECS
- UY8720000
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- Solid
- pka
- 14.66±0.30(Predicted)
- Appearance
- Off-white to light brown Solid
- Water Solubility
- Soluble in water (hardly), methanol and chloroform.
- Sensitive
- Air & Light Sensitive
- InChI
- InChI=1S/C7H6N2/c1-3-8-5-7-6(1)2-4-9-7/h1-5,9H
- InChIKey
- XLKDJOPOOHHZAN-UHFFFAOYSA-N
- SMILES
- C1=NC=CC2C=CNC1=2
- CAS DataBase Reference
- 271-29-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant
- HS Code
- 29339980
- Toxicity
- mouse,LD50,intraperitoneal,12mg/kg (12mg/kg),Journal of Medicinal Chemistry. Vol. 6, Pg. 480, 1963.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- CDS007514
- Product name
- 1<I>H</I>-Pyrrolo[2,3-<I>c</I>]pyridine
- Purity
- Aldrich<SUP>CPR</SUP>
- Packaging
- 1 g
- Price
- $286
- Updated
- 2025/07/31
- Product number
- P2530
- Product name
- 1H-Pyrrolo[2,3-c]pyridine
- Purity
- min. 98.0 %
- Packaging
- 1G
- Price
- $43
- Updated
- 2025/07/31
- Product number
- P2530
- Product name
- 1H-Pyrrolo[2,3-c]pyridine
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $130
- Updated
- 2025/07/31
- Product number
- A965395
- Product name
- 6-Azaindole
- Packaging
- 2.5g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- A965395
- Product name
- 6-Azaindole
- Packaging
- 25g
- Price
- $335
- Updated
- 2021/12/16
6-Azaindole Chemical Properties,Usage,Production
Chemical Properties
crystals
Uses
6-Azaindole is an indole derivative and useful synthetic intermediate.
Synthesis
357263-41-3
271-29-4
General procedure for the synthesis of 6-azaindole using 7-chloro-1H-pyrrolo[2,3-c]pyridine as starting material: a suspension of 7-chloro-1H-pyrrolo[2,3-c]pyridine (650 mg, 4.2 mmol) with 10% Pd/C (50 mg) in ethanol (25 mL) was subjected to a hydrogen atmosphere (balloon pressure) and the reaction was stirred at room temperature. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filter cake was washed with ethyl acetate (10 mL). The filtrates were combined, concentrated under reduced pressure and subsequently purified by fast column chromatography (eluent: dichloromethane/methanol/ammonia, 9:1:0.1, v/v) to afford 1H-pyrrolo[2,3-c]pyridine as a white solid (380 mg, 75% yield).
References
[1] Journal of Organic Chemistry, 2002, vol. 67, # 7, p. 2345 - 2347
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 22, p. 9531 - 9540
[3] Patent: US2007/123535, 2007, A1. Location in patent: Page/Page column 43
[4] European Journal of Medicinal Chemistry, 2011, vol. 46, # 10, p. 5086 - 5098
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 10, p. 4009 - 4022
6-Azaindole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-Azaindole manufacturers
- Product
- 6-Azaindole 271-29-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-04-12
- Product
- 6-Azaindole 271-29-4
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-29
- Product
- 6-Azaindole 271-29-4
- Price
- US $100.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2021-09-14