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BOC-D-ABU-OH

Product Name
BOC-D-ABU-OH
CAS No.
45121-22-0
Chemical Name
BOC-D-ABU-OH
Synonyms
BOC-D-ABU;BOC-D-ABU-OH;BOC-D-2-ABU-OH;BOC-D-ABU(2)-OH;BOC-D-ALPHA-ABU-OH;BOC-D-ABU(ALPHA)-OH;BOC-D-ABU-OH USP/EP/BP;BOC-D-AMINOBUTYRIC ACID;BOC-D-NHCH(CH2CH3)-COOH;BOC-D-2-AMINOBUTYRIC ACID
CBNumber
CB9690640
Molecular Formula
C9H17NO4
Formula Weight
203.24
MOL File
45121-22-0.mol
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BOC-D-ABU-OH Property

Boiling point:
334.5±25.0 °C(Predicted)
Density 
1.101
storage temp. 
Sealed in dry,2-8°C
solubility 
Soluble in DMF (1mmol in 1ml DMF).
form 
Liquid
pka
4.00±0.10(Predicted)
color 
Yellow
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Safety

HazardClass 
IRRITANT
HS Code 
2924190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
265235
Product name
Boc-D-a-aminobutyric acid
Packaging
2g
Price
$353
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB49466
Product name
Boc-D-a-aminobutyric acid
Packaging
100g
Price
$400
Updated
2021/12/16
Chem-Impex
Product number
11351
Product name
Boc-D-a-aminobutyricacid,≥98%(HPLC)
Purity
≥98%(HPLC)
Packaging
250G
Price
$541.63
Updated
2021/12/16
Apolloscientific
Product number
OR911736
Product name
(R)-Boc-2-aminobutyricacid
Purity
97%
Packaging
100g
Price
$588
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0034027
Product name
BOC-D-ABU-OH
Purity
95.00%
Packaging
1G
Price
$697.62
Updated
2021/12/16
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BOC-D-ABU-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

(R)-2-(Boc-amino)butyric acid is used in coupling reaction. Also used in preparation of dyes.

Synthesis

2623-91-8

24424-99-5

45121-22-0

[Step 1] Synthesis of (R)-2-((tert-butoxycarbonyl)amino)butanoic acid Di-tert-butyl dicarbonate (4.7 g, 21 mmol) was slowly added to a mixed solution of (R)-2-aminobutyric acid (2.0 g, 19 mmol) and sodium bicarbonate (1.6 g, 19 mmol) in a mixture of 1,4-dioxane and water (3:10 v/v/v, total 26 mL) under ice bath cooling. The reaction mixture was stirred at room temperature for 120 hours and then concentrated under reduced pressure. The resulting crude product was dissolved in chloroform, to which 1N hydrochloric acid was subsequently added and extracted with chloroform. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 2.0 g (quantitative yield) of the title compound (hereinafter referred to as Reference Example Compound 27).

References

[1] Patent: EP2832724, 2015, A1. Location in patent: Paragraph 0169
[2] European Journal of Organic Chemistry, 2002, # 23, p. 3995 - 4004
[3] Journal of the American Chemical Society, 1997, vol. 119, # 4, p. 656 - 673
[4] Bioorganic and Medicinal Chemistry Letters, 1999, vol. 9, # 22, p. 3237 - 3242
[5] Tetrahedron, 2006, vol. 62, # 42, p. 9966 - 9972

BOC-D-ABU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-D-ABU-OH Suppliers

Senn Chemicals AG
Tel
--
Fax
--
Email
swiss@sennchem.com
Country
Switzerland
ProdList
3143
Advantage
71
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View Lastest Price from BOC-D-ABU-OH manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
BOC-D-ABU-OH 45121-22-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-10-09
Career Henan Chemical Co
Product
BOC-D-ABU-OH 45121-22-0
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-22

45121-22-0, BOC-D-ABU-OHRelated Search:


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  • BOC-D-ABU(2)-OH
  • BOC-D-ABU(ALPHA)-OH
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  • BOC-D-2-AMINOBUTANOIC ACID
  • BOC-D-2-ABU-OH
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  • N-ALPHA-T-BUTOXYCARBONYL-D-2-AMINO-BUTYRIC ACID
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  • (R)-Boc-2-aMinobutyric acid
  • N-Boc-D-2-aMinobutyric acid
  • (R)-2-(Boc-aMino)butyric acid, 95%
  • (R)-2-((tert-Butoxycarbonyl)aMino)butanoic acid
  • Boc-D-a-aminobutyric acid
  • Boc-D-a-aminobutyric acid≥ 98% (HPLC)
  • (Tert-Butoxy)Carbonyl D-Abu-OH
  • Butanoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, (2R)-
  • (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
  • (R)-2-(Boc-amino)butyricacid,95%
  • (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoicaci
  • BOC-D-2-ABU-OH, 45121-22-0
  • BOC-D-ABU-OH USP/EP/BP
  • (2R)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]butanoic acid
  • (2R)-2-[N-BOC-Amino]butanoic acid
  • 45121-22-0
  • CH17NO4