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ARTEPILLIN C

Product Name
ARTEPILLIN C
CAS No.
72944-19-5
Chemical Name
ARTEPILLIN C
Synonyms
ARTEPILLIN C;Artemisia annua C;ArtepillinC,fromPropolis;ARTEPILLIN C500Mg, 1g, 5g.;3,5-Diprenyl-4-hydroxycinnamic acid;3,5-Diprenyl-4-hydroxy-trans-cinnamic acid;4-Hydroxy-3,5-bis(3-methyl-2-butenyl)cinnamic acid;3,5-Bis(3-methyl-2-butenyl)-4-hydroxy-trans-cinnamic acid;(E)-3-[4-Hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]propenoic acid;(E)-3-(4-hydroxy-3,5-bis(3-methylbut-2-en-1-yl)phenyl)acrylic acid
CBNumber
CB9695483
Molecular Formula
C19H24O3
Formula Weight
300.39
MOL File
72944-19-5.mol
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ARTEPILLIN C Property

Melting point:
98-99 °C
Boiling point:
447.7±40.0 °C(Predicted)
Density 
1.092±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Acetonitrile: Soluble
DMSO: Soluble
pka
4.69±0.10(Predicted)
form 
solid
color 
Light yellow to yellow
InChI
InChI=1S/C19H24O3/c1-13(2)5-8-16-11-15(7-10-18(20)21)12-17(19(16)22)9-6-14(3)4/h5-7,10-12,22H,8-9H2,1-4H3,(H,20,21)/b10-7+
InChIKey
KABCFARPAMSXCC-JXMROGBWSA-N
SMILES
C(O)(=O)/C=C/C1=CC(C/C=C(/C)\C)=C(O)C(C/C=C(/C)\C)=C1
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0015763
Product name
ARTEPILLIN C
Purity
95.00%
Packaging
5MG
Price
$501.6
Updated
2021/12/16
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ARTEPILLIN C Chemical Properties,Usage,Production

Uses

Artepillin C has gastroprotective, anti-inflammatory, antimicrobial, antioxidant, antitumor and choleretic activity. Artepillin C can be isolated from Brazilian green propolis[1][2].

References

[1] Kobal MB,et al. Correlating Artepillin C cytotoxic activity on HEp-2 cells with bioinspired systems of plasma membranes. Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110943. DOI:10.1016/j.msec.2020.110943
[2] Beserra FP, et al. Artepillin C as an outstanding phenolic compound of Brazilian green propolis for disease treatment: A review on pharmacological aspects. Phytother Res. 2020 Sep 15. DOI:10.1002/ptr.6875
[3] SATOSHI ENDO*. Selective Inhibition of Human Type-5 17β-Hydroxysteroid Dehydrogenase (AKR1C3) by Baccharin, a Component of Brazilian Propolis[J]. Journal of Natural Products , 2012, 75 4: 716-721. DOI: 10.1021/np201002x
[4] ALEJANDRO TAPIA . Free radical scavengers and antioxidants from Baccharis grisebachii[J]. Journal of ethnopharmacology, 2004, 95 2: Pages 155-161. DOI: 10.1016/j.jep.2004.06.035
[5] TAKETOSHI HATA. Artepillin C, a major ingredient of Brazilian propolis, induces a pungent taste by activating TRPA1 channels.[J]. PLoS ONE, 2012: e48072. DOI: 10.1371/journal.pone.0048072
[6] ARJUN H. BANSKOTA. Chemical Constituents of Brazilian Propolis and Their Cytotoxic Activities[J]. Journal of Natural Products , 1998, 61 7: 896-900. DOI: 10.1021/np980028c
[7] GABRIELA EGLY FERESIN . Constituents of the Argentinian medicinal plant Baccharis grisebachii and their antimicrobial activity[J]. Journal of ethnopharmacology, 2003, 89 1: Pages 73-80. DOI: 10.1016/s0378-8741(03)00259-9
[8] NIRALDO PAULINO . Anti-inflammatory effects of a bioavailable compound, Artepillin C, in Brazilian propolis[J]. European journal of pharmacology, 2008, 587 1: Pages 296-301. DOI: 10.1016/j.ejphar.2008.02.067

ARTEPILLIN C Preparation Products And Raw materials

Raw materials

Preparation Products

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ARTEPILLIN C Suppliers

Chengdu Alfa Biotechnology Co.,Ltd.
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028-028-85142057 19983342022
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Nanjing Chemlin Chemical Co., Ltd
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028-81700200 18116577057
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Shanghai Kewel Chemical Co., Ltd.
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021-64609169 18901607656
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Wuhan ChemFaces Biochemical Co., Ltd.
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Chengdu Push Bio-Technology Co., Ltd.
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Nanjing Digger Medical Technology Co. Ltd.
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Career Henan Chemica Co
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72944-19-5, ARTEPILLIN CRelated Search:


  • ARTEPILLIN C500Mg, 1g, 5g.
  • ArtepillinC,fromPropolis
  • (E)-3-[4-Hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]propenoic acid
  • 3,5-Bis(3-methyl-2-butenyl)-4-hydroxy-trans-cinnamic acid
  • 3,5-Diprenyl-4-hydroxycinnamic acid
  • 3,5-Diprenyl-4-hydroxy-trans-cinnamic acid
  • 4-Hydroxy-3,5-bis(3-methyl-2-butenyl)cinnamic acid
  • ARTEPILLIN C
  • 2-Propenoic acid, 3-[4-hydroxy-3,5-bis(3-methyl-2-buten-1-yl)phenyl]-, (2E)-
  • (E)-3-(4-hydroxy-3,5-bis(3-methylbut-2-en-1-yl)phenyl)acrylic acid
  • Artemisia annua C
  • 72944-19-5