ARTEPILLIN C
- Product Name
- ARTEPILLIN C
- CAS No.
- 72944-19-5
- Chemical Name
- ARTEPILLIN C
- Synonyms
- ARTEPILLIN C;Artemisia annua C;ArtepillinC,fromPropolis;ARTEPILLIN C500Mg, 1g, 5g.;3,5-Diprenyl-4-hydroxycinnamic acid;3,5-Diprenyl-4-hydroxy-trans-cinnamic acid;4-Hydroxy-3,5-bis(3-methyl-2-butenyl)cinnamic acid;3,5-Bis(3-methyl-2-butenyl)-4-hydroxy-trans-cinnamic acid;(E)-3-[4-Hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]propenoic acid;(E)-3-(4-hydroxy-3,5-bis(3-methylbut-2-en-1-yl)phenyl)acrylic acid
- CBNumber
- CB9695483
- Molecular Formula
- C19H24O3
- Formula Weight
- 300.39
- MOL File
- 72944-19-5.mol
ARTEPILLIN C Property
- Melting point:
- 98-99 °C
- Boiling point:
- 447.7±40.0 °C(Predicted)
- Density
- 1.092±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Acetonitrile: Soluble
DMSO: Soluble - pka
- 4.69±0.10(Predicted)
- form
- solid
- color
- Light yellow to yellow
- InChI
- InChI=1S/C19H24O3/c1-13(2)5-8-16-11-15(7-10-18(20)21)12-17(19(16)22)9-6-14(3)4/h5-7,10-12,22H,8-9H2,1-4H3,(H,20,21)/b10-7+
- InChIKey
- KABCFARPAMSXCC-JXMROGBWSA-N
- SMILES
- C(O)(=O)/C=C/C1=CC(C/C=C(/C)\C)=C(O)C(C/C=C(/C)\C)=C1
N-Bromosuccinimide Price
- Product number
- API0015763
- Product name
- ARTEPILLIN C
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.6
- Updated
- 2021/12/16
ARTEPILLIN C Chemical Properties,Usage,Production
Uses
Artepillin C has gastroprotective, anti-inflammatory, antimicrobial, antioxidant, antitumor and choleretic activity. Artepillin C can be isolated from Brazilian green propolis[1][2].
References
[1] Kobal MB,et al. Correlating Artepillin C cytotoxic activity on HEp-2 cells with bioinspired systems of plasma membranes. Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110943. DOI:10.1016/j.msec.2020.110943
[2] Beserra FP, et al. Artepillin C as an outstanding phenolic compound of Brazilian green propolis for disease treatment: A review on pharmacological aspects. Phytother Res. 2020 Sep 15. DOI:10.1002/ptr.6875
[3] SATOSHI ENDO*. Selective Inhibition of Human Type-5 17β-Hydroxysteroid Dehydrogenase (AKR1C3) by Baccharin, a Component of Brazilian Propolis[J]. Journal of Natural Products , 2012, 75 4: 716-721. DOI: 10.1021/np201002x
[4] ALEJANDRO TAPIA . Free radical scavengers and antioxidants from Baccharis grisebachii[J]. Journal of ethnopharmacology, 2004, 95 2: Pages 155-161. DOI: 10.1016/j.jep.2004.06.035
[5] TAKETOSHI HATA. Artepillin C, a major ingredient of Brazilian propolis, induces a pungent taste by activating TRPA1 channels.[J]. PLoS ONE, 2012: e48072. DOI: 10.1371/journal.pone.0048072
[6] ARJUN H. BANSKOTA. Chemical Constituents of Brazilian Propolis and Their Cytotoxic Activities[J]. Journal of Natural Products , 1998, 61 7: 896-900. DOI: 10.1021/np980028c
[7] GABRIELA EGLY FERESIN . Constituents of the Argentinian medicinal plant Baccharis grisebachii and their antimicrobial activity[J]. Journal of ethnopharmacology, 2003, 89 1: Pages 73-80. DOI: 10.1016/s0378-8741(03)00259-9
[8] NIRALDO PAULINO . Anti-inflammatory effects of a bioavailable compound, Artepillin C, in Brazilian propolis[J]. European journal of pharmacology, 2008, 587 1: Pages 296-301. DOI: 10.1016/j.ejphar.2008.02.067
ARTEPILLIN C Preparation Products And Raw materials
Raw materials
Preparation Products
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