TDZD-8

Product Name
TDZD-8
Chemical Name
TDZD-8
Synonyms
TDZD-8;GSK-3BETA INHIBITOR I;4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE
CBNumber
CB9702181
Molecular Formula
C10H10N2O2S
Formula Weight
222.26
MOL File
Mol file
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TDZD-8 Property

Melting point:
63-64.4 °C
storage temp. 
2-8°C
solubility 
DMSO: 18 mg/mL
form 
needles
color 
white
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Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
36/37
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
B1078-01E
Product name
4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
Packaging
10mg
Price
$333
Updated
2021/12/16
Biorbyt Ltd
Product number
orb146107
Product name
TDZD-8
Purity
>98%
Packaging
100mg
Price
$615.4
Updated
2021/12/16
Biorbyt Ltd
Product number
orb146107
Product name
TDZD-8
Purity
>98%
Packaging
1g
Price
$1949.9
Updated
2021/12/16
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TDZD-8 Chemical Properties,Usage,Production

Uses

A thiadiazolidinone (TDZD) analog that acts as a highly selective, non-ATP competitive inhibitor of GSK-3

Uses

Glycogen Synthase Kinase-3? is a highly conserved ubiquitously expressed serine/threonine protein kinase involved in signal transduction cascades of multiple cellular processes. TDZD-8 is a thiadiazolidinone (TDZD) analogue that acts as a highly selective, non-ATP competitive inhibitor of GSK-3? ( IC50 =2nM). Binds to the active site of GSK-3?. Does not significantly affect the activities of Cdk-1/cyclin B, CK-II, PKA, and PKC (IC50 >100nM).

TDZD-8 Preparation Products And Raw materials

Raw materials

Preparation Products

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TDZD-8 Suppliers

SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74
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View Lastest Price from TDZD-8 manufacturers

Career Henan Chemical Co
Product
TDZD-8 7036-89-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23