ChemicalBook > CAS DataBase List > Z-PHE-DL-ALA-FLUOROMETHYLKETONE

Z-PHE-DL-ALA-FLUOROMETHYLKETONE

Product Name
Z-PHE-DL-ALA-FLUOROMETHYLKETONE
CAS No.
197855-65-5
Chemical Name
Z-PHE-DL-ALA-FLUOROMETHYLKETONE
Synonyms
CS-1504;Z-Phe-DL-Ala-FMK;Z-PHE-DL-ALA-FLUOROMETHYLKETONE;Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide;Benzyl ((2S)-1-((4-fluoro-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate;Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide z-fa-fmk;Carbamic acid,N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-,phenylmethyl ester;SARS coronavirus,SARS-CoV,RRMs,DNA fragmentation,DEVDase,Caspase,Cathepsin,Inhibitor,externalization of phosphatidylserine,Apoptosis,inhibit,Z FA FMK,reovirus replication,ZFAFMK
CBNumber
CB9710726
Molecular Formula
C21H23FN2O4
Formula Weight
386.42
MOL File
197855-65-5.mol
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Z-PHE-DL-ALA-FLUOROMETHYLKETONE Property

Boiling point:
630.5±55.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMF: 5 mg/ml; DMSO: 5 mg/ml
form 
White solid
pka
11.07±0.46(Predicted)
color 
White to off-white
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Safety

HS Code 
29145090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14462
Product name
Z-FA-FMK
Purity
≥98%
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
14462
Product name
Z-FA-FMK
Purity
≥98%
Packaging
5mg
Price
$253
Updated
2024/03/01
TRC
Product number
Z350000
Product name
Z-FA-FMK
Packaging
25mg
Price
$790
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
49262
Product name
Z-FA-FMK
Packaging
5mg
Price
$830
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0009036
Product name
Z-PHE-DL-ALA-FLUOROMETHYLKETONE
Purity
98.00%
Packaging
10MG
Price
$1478.4
Updated
2021/12/16
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Z-PHE-DL-ALA-FLUOROMETHYLKETONE Chemical Properties,Usage,Production

Description

Z-FA-FMK is an irreversible inhibitor of cysteine proteases, including cathepsins B, L, and S, cruzain, and papain. It also inhibits effector caspases-2, -3, -6, and -7 (IC50 = 6-32 μM) without affecting the initiator caspases-8 and -10. Z-FA-FMK also modulates infection by certain bacteria, parasites, and viruses. It can be used both in cells and in vivo.

Uses

Z-FA-FMK is an irreversible cysteine protease inhibitor. It also inhibits papain and cruzain.

Z-PHE-DL-ALA-FLUOROMETHYLKETONE Preparation Products And Raw materials

Raw materials

Preparation Products

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Z-PHE-DL-ALA-FLUOROMETHYLKETONE Suppliers

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197855-65-5, Z-PHE-DL-ALA-FLUOROMETHYLKETONERelated Search:


  • Z-PHE-DL-ALA-FLUOROMETHYLKETONE
  • Carbamic acid,N-[(1S)-2-[(3-fluoro-1-methyl-2-oxopropyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-,phenylmethyl ester
  • Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide z-fa-fmk
  • Nalpha-[(Benzyloxy)Carbonyl]-N-(4-Fluoro-3-Oxo-2-Butanyl)Phenylalaninamide
  • CS-1504
  • Z-Phe-DL-Ala-FMK
  • Benzyl ((2S)-1-((4-fluoro-3-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate
  • SARS coronavirus,SARS-CoV,RRMs,DNA fragmentation,DEVDase,Caspase,Cathepsin,Inhibitor,externalization of phosphatidylserine,Apoptosis,inhibit,Z FA FMK,reovirus replication,ZFAFMK
  • 197855-65-5
  • C21H23FN2O4
  • Inhibitors
  • API