Esomeprazole magnesium trihydrate

Product Name: Esomeprazole magnesium trihydrate
CAS No.: 217087-09-7
Chemical Name: Esomeprazole magnesium trihydrate
Synonyms: Nexium;EsomepazoleTrihydrate;Esomeprazole Mg Trihydrate;ESOPMEPRAZOLE MG TRIHYDRATE;EsoMeprazole Meg. Trihydrate;Omeprazole 8.5%/12.5% pellels;Esomeprazole Magnesium (10 mg);Esomeprazole Magnesium (25 mg);Omeprazole Magnesium Trihydrate;EsoMeprazole Magnesiu Trihydrate
CBNumber: CB9740619
Molecular Formula: C34H38MgN6O7S2
Formula Weight: 731.14
MOL File: 217087-09-7.mol

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Esomeprazole magnesium trihydrate Property

Melting point:: 184-189°C (dec.)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: Slightly soluble in water, soluble in methanol, practically insoluble in heptane.
form: Solid
color: White to off-white
InChI: InChI=1S/2C17H18N3O3S.Mg.H2O/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;;/h2*5-8H,9H2,1-4H3;;1H2/q2*-1;+2;
InChIKey: VEVZQDGATGBLIC-UHFFFAOYSA-N
SMILES: C(C1N=CC(C)=C(OC)C=1C)S1C2[N-]C3=CC(OC)=CC=C3N=2[Mg+2]2(O=S(CC3N=CC(C)=C(OC)C=3C)C3[N-]C4=CC(OC)=CC=C4N2=3)O=1.O
CAS DataBase Reference: 217087-09-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HS Code: 2933399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR1585
Product name: Esomeprazole Magnesium
Packaging: 1g
Price: $193
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1249789
Product name: Esomeprazole magnesium
Purity: UnitedStatesPharmacopeia(USP)ReferenceStandard
Packaging: 100MG
Price: $483
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0001028
Product name: Esomeprazole magnesium trihydrate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001028
Price: $154
Updated: 2024/03/01

ChemScene

Product number: CS-1024
Product name: Esomeprazole magnesium trihydrate
Packaging: 50mg
Price: $156
Updated: 2021/12/16

ApexBio Technology

Product number: A3399
Product name: Esomeprazole magnesium trihydrate
Packaging: 50mg
Price: $205
Updated: 2021/12/16

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Esomeprazole magnesium trihydrate Chemical Properties,Usage,Production

Chemical Properties

Off-White Powder

Uses

S-Form of Omeprazole. Gastric proton-pump inhibitor

Uses

Esomeprazole Magnesium Trihydrate is used in preparation of esomeprazole magnesium trihydrate.

Uses

esomeprazole magnesium trihydrate for the healing of peptic ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.

Zollinger-Ellison syndrome
Peptic ulcer, site unspecified
Duodenal ulcer
Gastric ulcer
Gastro-oesophageal reflux disease

Esomeprazole belongs to the family of medications known as proton pump inhibitors (PPIs). Esomeprazole is registered by the Therapeutic Goods Administration (TGA) for the following indications:

Gastro-Oesophageal Reflux Disease (GORD):
treatment of erosive reflux oesophagitis;
long-term management of patients with healed oesophagitis to prevent relapse;
symptomatic treatment of gastro-oesophageal reflux disease (GORD).

In combination with appropriate antibiotics for:

healing of duodenal ulcer associated with Helicobacter pylori;
eradication of Helicobacter pylori in patients with active or healed peptic ulcer.
Short-term treatment of upper gastrointestinal symptoms associated with non-steroidal anti-inflammatory drug (NSAID) (non-selective and COX-2 selective) therapy.
Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy.
Prevention of gastric and duodenal ulcers associated with non-steroidal anti-inflammatory drug NSAID (non-selective and COX-2 selective) therapy in patients at risk.

brand name

Nexium (AstraZeneca).

Biological Activity

Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent, orally active H+, K+-ATPase inhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research. Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release by inhibiting V-H+-ATPases.

Esomeprazole magnesium trihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Esomeprazole magnesium trihydrate Suppliers

Canada 1 China 325 France 2 Germany 3 India 67 Italy 1 South Korea 1 United Kingdom 5 United States 26 Global 431

CHEMICAL LAND21

Tel: --
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Email: sales21@chemicalland21.com
Country: South Korea
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View Lastest Price from Esomeprazole magnesium trihydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Esomeprazole magnesium trihydrate 217087-09-7
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%-102%
Supply Ability: 500kgs
Release date: 2021-07-09

Sinoway Industrial co., ltd.

Product: Esomeprazole Magnesium Trihydrate 217087-09-7
Price: US $0.00/Kg/Bag
Min. Order: 2Kg/Bag
Purity: 99% up, EP9.0, CEP
Supply Ability: 20 tons
Release date: 2022-08-12

Hebei Yanxi Chemical Co., Ltd.

Product: Esomeprazole magnesium trihydrate 217087-09-7
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2023-10-23

217087-09-7, Esomeprazole magnesium trihydrateRelated Search:

ESOMEPRAZOLE MAGNESIUM TRIHYDRATE

bis(5-methoxy-2-[(s)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1h-benzylimidazole-1-yl) magnesium trihydrate

(T-4)-Bis[5-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazolato]magnesium

Nexium

ESOPMEPRAZOLE MG TRIHYDRATE

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217087-09-7

C34H42MgN6O9S2

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71312

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