D(+)-Phenylalaninol
Detected method- Product Name
- D(+)-Phenylalaninol
- CAS No.
- 5267-64-1
- Chemical Name
- D(+)-Phenylalaninol
- Synonyms
- D-PHENYLALANINOL;H-D-PHE-OL;D-Phenylalanino;(R)-2-AMINO-3-PHENYL-1-PROPANOL;(2R)-2-amino-3-phenylpropan-1-ol;(R)-2-AMINO-3-PHENYL-PROPAN-1-OL;H-D-Phen-ol;R-228060-001;D-PHENYLANINOL;D-PHEYLALANINOL
- CBNumber
- CB9741308
- Molecular Formula
- C9H13NO
- Formula Weight
- 151.21
- MOL File
- 5267-64-1.mol
D(+)-Phenylalaninol Property
- Melting point:
- 93-95 °C(lit.)
- Boiling point:
- 122 °C / 4mmHg
- alpha
- 23 º (c=1.2, 1 N HCl 22 ºC)
- Density
- 1.0406 (rough estimate)
- refractive index
- 23.5 ° (C=1.2, 1mol/L HCl)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- Soluble in Dichloromethane, Ethyl Acetate, Methanol.
- form
- Crystalline Powder and Chunks
- pka
- 12.85±0.10(Predicted)
- color
- White to yellow
- optical activity
- [α]/D +22.8°, c = 1.2 in 1 M HCl
- Sensitive
- Air Sensitive
- BRN
- 4665408
- InChI
- InChI=1/C9H13NO/c10-9(7-11)6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2/t9-/s3
- InChIKey
- STVVMTBJNDTZBF-DJEYLCQNNA-N
- SMILES
- C(C1C=CC=CC=1)[C@@H](N)CO |&1:7,r|
- CAS DataBase Reference
- 5267-64-1(CAS DataBase Reference)
Safety
- Hazard Codes
- C,Xi
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45-27
- RIDADR
- UN 3259 8/PG 3
- WGK Germany
- 3
- F
- 10-23
- HazardClass
- IRRITANT
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29221990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- 284491
- Product name
- (R)-(+)-2-Amino-3-phenyl-1-propanol
- Purity
- 98%
- Packaging
- 5g
- Price
- $142
- Updated
- 2023/01/07
- Product number
- P1289
- Product name
- D-Phenylalaninol
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $72
- Updated
- 2024/03/01
- Product number
- P1289
- Product name
- D-Phenylalaninol
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $218
- Updated
- 2024/03/01
- Product number
- L09697
- Product name
- D-Phenylalaninol, 98%
- Packaging
- 1g
- Price
- $40.65
- Updated
- 2024/03/01
- Product number
- 019430
- Product name
- D-Phenylalaninol
- Packaging
- 5g
- Price
- $403
- Updated
- 2021/12/16
D(+)-Phenylalaninol Chemical Properties,Usage,Production
Detected method
Phenomena, including gelation and fluorescence, are used as easily detected sensors of chiral recognition. Qin et al. have developed a new type of isomerized diphenylalanine-based supramolecular gel (LFDF), which showed the visible enantiomeric discrimination of phenylalaninol enantiomers via fluorescence and gelation measurements. The addition of L- or D-phenylalaninol to the peptide gel led to complete collapse within one minute after adding the L-form, which was not observed in D-phenylalaninol. Meanwhile, by doping with the fluorescent dye thioflavin T (ThT), the prepared ThT-LFDF gel system can sensitively detect the L/D-phenylalanine enantiomer through fluorescence quenching, which has the advantages of visualization, easy manipulation, and high detection sensitivity.
Description
D-phenylalanine is the D-enantiomer of phenylalanine. It is a conjugate base of a D-phenylalaninium and an enantiomer of a L-phenylalanine. D-Phenylalanine is a metabolite found in or produced by Escherichia coli (strain K12, MG1655). It may be light-sensitive. This compound reacts with strong oxidizing agents, acids and bases. It acts as a weak acid in solution.
Chemical Properties
white to light yellow crystal powde
Uses
D-Phenylalaninol is used as a chiral auxiliary for asymmetric Michael reactions. It is an enantiomer of L-Phenylalaninol, an inhibitor of intestinal Phenylalanine absorption. It acts as an inhibiting agent to the enzymes which are responsible for the breakdown of endorphins.
Purification Methods
It can be recrystallised from Et2O, *C6H6/pet ether (b 40-60o) or toluene and distilled in a vacuum. It has been purified by dissolving in Et2O, drying over K2CO3, filtering, evaporating to a small volume, cooling in ice and collecting the plates. Store them in the presence of KOH (i.e. CO2—free atm). [Karrer & Ehrhardt Helv Chim Acta 34 3203 1951, Oeda Bull Chem Soc Jpn 13 465 1938.] The picrate has m 141-141.5o (from EtOH/pet ether). The hydrogen oxalate has m 177o, 161-162o [Hunt & McHale J Chem Soc 2073 1957]. The racemate has m 87-88o from *C6H6/pet ether (75-77o from Et2O), and the hydrochloride has m 139-141o [Fodor et al. J Chem Soc 1858 1951]. [Beilstein 13 IV 1920.]
D(+)-Phenylalaninol Preparation Products And Raw materials
Raw materials
Preparation Products
D(+)-Phenylalaninol Suppliers
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- Country
- France
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View Lastest Price from D(+)-Phenylalaninol manufacturers
- Product
- D(+)-Phenylalaninol 5267-64-1
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kg
- Release date
- 2021-08-28
- Product
- d-phe-ol 5267-64-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-01-20
- Product
- D(+)-Phenylalaninol 5267-64-1
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-23