Synthesis
ChemicalBook > CAS DataBase List > 3-Chloro-4-fluoronitrobenzene

3-Chloro-4-fluoronitrobenzene

Synthesis
Product Name
3-Chloro-4-fluoronitrobenzene
CAS No.
350-30-1
Chemical Name
3-Chloro-4-fluoronitrobenzene
Synonyms
2-CHLORO-1-FLUORO-4-NITROBENZENE;3-Chloro-4-fluoronit;Gefitinib Impurity 92;3-chloro-4-fluorobenzene;3-CHLORO-4-FLUORONITROANILINE;4-FLUORO-3-CHLORONITROBENZENE;3-CHLORO-4-FLUORONITROBENZENE;3-chioro-4-fluoronitrobenzene;1-CHLORO-2-FLUORO-5-NITROBENZENE;2-chloro-1-fluoro-4-nitro-benzen
CBNumber
CB9743847
Molecular Formula
C6H3ClFNO2
Formula Weight
175.54
MOL File
350-30-1.mol
More
Less

3-Chloro-4-fluoronitrobenzene Property

Melting point:
40-42 °C(lit.)
Boiling point:
227-232°C
Density 
1.61
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
color 
White to Light yellow to Green
BRN 
1944997
CAS DataBase Reference
350-30-1(CAS DataBase Reference)
NIST Chemistry Reference
3-Chloro-4-fluoronitrobenzene(350-30-1)
EPA Substance Registry System
3-Chloro-4-fluoronitrobenzene (350-30-1)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-37/38-41-36/37/38-20/21/22
Safety Statements 
26-39-36/37/39
RIDADR 
2811
WGK Germany 
3
RTECS 
CZ0720000
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29049090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
233234
Product name
2-Chloro-1-fluoro-4-nitrobenzene
Purity
98%
Packaging
25g
Price
$204
Updated
2024/03/01
TCI Chemical
Product number
C1041
Product name
3-Chloro-4-fluoronitrobenzene
Purity
>95.0%(GC)
Packaging
25g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
C1041
Product name
3-Chloro-4-fluoronitrobenzene
Purity
>95.0%(GC)
Packaging
250g
Price
$96
Updated
2024/03/01
Alfa Aesar
Product number
A16183
Product name
2-Chloro-1-fluoro-4-nitrobenzene, 98%
Packaging
50g
Price
$69.9
Updated
2021/12/16
Alfa Aesar
Product number
A16183
Product name
2-Chloro-1-fluoro-4-nitrobenzene, 98%
Packaging
25g
Price
$46.5
Updated
2021/12/16
More
Less

3-Chloro-4-fluoronitrobenzene Chemical Properties,Usage,Production

Synthesis

In certain instances, when both chloro and nitro may act as a leaving group, a surprising selectivity of one over the other is observed, for example chloro-2,5- dinitrobenzene was converted to 4-fluoro-3-chloronitrobenzene.

Chemical Properties

white to light yellow crystal powder

Uses

2-Chloro-1-fluoro-4-nitrobenzene is an intermediate used in synthesis of benzoimidolones on Ameba resin and methyl 6,7,8,9-tetrahydropyrido[1,2-a]indol-10-ylacetate.

Uses

2-Chloro-1-fluoro-4-nitrobenzene has been used in synthesis of:

  • benzoimidolones on Ameba resin
  • methyl 6,7,8,9-tetrahydropyrido[1,2-a]indol-10-ylacetate

Synthesis Reference(s)

The Journal of Organic Chemistry, 63, p. 8448, 1998 DOI: 10.1021/jo981557o
Synthetic Communications, 21, p. 505, 1991 DOI: 10.1080/00397919108016776

General Description

2-Chloro-1-fluoro-4-nitrobenzene undergoes reduction in the presence of Mo(CO)6 and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) under microwave irradiation to yield a mixture of 3-chloro-4-fluoroaniline and 3-chloro-4-ethoxyaniline.

3-Chloro-4-fluoronitrobenzene Preparation Products And Raw materials

Raw materials

4-Fluoronitrobenzene Fluorobenzene

Preparation Products

Norfloxacin 1,3-Dichloro-4-fluorobenzene
More
Less

3-Chloro-4-fluoronitrobenzene Suppliers

Americas 1 Belgium 2 Canada 3 China 279 Europe 4 France 2 Germany 4 India 17 Italy 1 Japan 4 Slovakia 1 South Korea 1 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 15 United States 49 Global 388
Portail Substances Chimiques
Tel
--
Fax
--
Email
webmestre-substances@ineris.fr
Country
France
ProdList
6024
Advantage
58
Interchim S.A.
Tel
--
Fax
--
Email
interchim@interchim.com
Country
France
ProdList
6302
Advantage
76
More
Less

View Lastest Price from 3-Chloro-4-fluoronitrobenzene manufacturers

Henan Fengda Chemical Co., Ltd
Product
3-Chloro-4-fluoronitrobenzene 350-30-1
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-25
Baoji Guokang Healthchem co.,ltd
Product
3-Chloro-4-fluoronitrobenzene 350-30-1
Price
US $79.00/KG
Min. Order
1KG
Purity
99
Supply Ability
10T
Release date
2021-06-07
Honest Joy Holdings Limited
Product
3-Chloro-4-fluoronitrobenzene 350-30-1
Price
US $0.00/KG
Min. Order
1KG
Purity
97.4%
Supply Ability
100 tons
Release date
2022-02-18

350-30-1, 3-Chloro-4-fluoronitrobenzeneRelated Search:

4-CHLORO-3-FLUORONITROBENZENE 4-(3-Chloropropyl)morpholine Isovanillin Benzonitrile, 5-methoxy-4-[3-(4-morpholinyl)propoxy]-2-nitro- 4-Chloro-3-fluoroaniline Benzonitrile, 2-amino-5-methoxy-4-[3-(4-morpholinyl)propoxy]- 3-Chloro-2-fluoroaniline 4-Fluoronitrobenzene Epichlorohydrin Cyhalothrin Cyhalothrin 1-Fluoro-2-nitrobenzene 1-Chloro-3-nitrobenzene Benzonitrile, 5-hydroxy-4-methoxy-2-nitro- 4-Chloronitrobenzene Nitrobenzene 2-Nitrochlorobenzene Difluorochloromethane

  • 2-chloro-1-fluoro-4-nitro-benzen
  • Benzene, 2-chloro-1-fluoro-4-nitro-
  • Benzene,2-chloro-1-fluoro-4-nitro-
  • 2-CHLORO-1-FLUORO-4-NITROBENZENE
  • 1-CHLORO-2-FLUORO-5-NITROBENZENE
  • 3-CHLORO-4-FLUORONITROBENZENE
  • 4-FLUORO-3-CHLORONITROBENZENE
  • 3-chloro-4-fluorobenzene
  • 3-CHLORO-4-FLUORONITROANILINE
  • 3-Chloro-4-fluoronitrobenzene 98%
  • 3-Chloro-4-fluoronitrobenzene98%
  • 1-Nitro-3-chloro-4-fluorobenzene
  • 1-Nitro-4-fluoro-3-chlorobenzene
  • 3-Chloro-4-fluoro-1-nitrobenzene
  • 3-Chloro-4-fluoronit
  • 3-chioro-4-fluoronitrobenzene
  • 3-Chloro-4-fluoronitrobenzene &gt
  • Gefitinib Impurity 92
  • 3-Chloro-4-fluoronitrobenzene ISO 9001：2015 REACH
  • 350-30-1
  • 350-31-1
  • C6H3ClFNO2
  • ClC6H3FNO2
  • Nitro Compounds
  • Organic Building Blocks
  • Nitrogen Compounds
  • Building Blocks
  • Fluorinated benzene series
  • Nitro Compounds
  • Nitrogen Compounds
  • Organic Building Blocks