ChemicalBook > CAS DataBase List > 4-Bromoaniline

4-Bromoaniline

Product Name
4-Bromoaniline
CAS No.
106-40-1
Chemical Name
4-Bromoaniline
Synonyms
P-BROMOANILINE;bromoaniline;4-Bromoanilines;4-BROMOBENZENAMINE;4-bromo-benzenamin;4-BroMo-phenylaMine;p-BROMOANILINE pure;4-BromoaniL;4-Bromanilinu;4-bromoanline
CBNumber
CB9760655
Molecular Formula
C6H6BrN
Formula Weight
172.02
MOL File
106-40-1.mol
More
Less

4-Bromoaniline Property

Melting point:
56-62 °C (lit.)
Boiling point:
230-250 °C
Density 
1.497
refractive index 
1.5680 (estimate)
Flash point:
222-224°C
storage temp. 
Store below +30°C.
solubility 
ethanol: soluble0.5g/10 mL, clear, colorless to almost colorless
form 
crystalline
pka
3.86(at 25℃)
color 
white to light yellow
Odor
Sweetish
Water Solubility 
<0.1 g/100 mL at 23 ºC
Merck 
14,1404
BRN 
742031
Dielectric constant
13.0（-7℃）
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, chloroformates. May be air sensitive.
InChIKey
WDFQBORIUYODSI-UHFFFAOYSA-N
CAS DataBase Reference
106-40-1(CAS DataBase Reference)
NIST Chemistry Reference
4-Bromoaniline(106-40-1)
EPA Substance Registry System
p-Bromoaniline (106-40-1)
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
21/22-36/37/38-20/21/22
Safety Statements 
26-36/37-36/37/39
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
BW9280000
F 
8-9-23
Hazard Note 
Harmful
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29214210
Hazardous Substances Data
106-40-1(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 456 mg/kg LD50 dermal Rat 536 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P314Get medical advice/attention if you feel unwell.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.01600
Product name
4-Bromoaniline
Purity
for synthesis
Packaging
100g
Price
$107
Updated
2024/03/01
Sigma-Aldrich
Product number
100900
Product name
4-Bromoaniline
Purity
97%
Packaging
5g
Price
$29.7
Updated
2024/03/01
Sigma-Aldrich
Product number
100900
Product name
4-Bromoaniline
Purity
97%
Packaging
100g
Price
$90.6
Updated
2024/03/01
Sigma-Aldrich
Product number
1.01599
Product name
4-Bromoaniline
Purity
GR for analysis
Packaging
25g
Price
$974
Updated
2022/05/15
TCI Chemical
Product number
B1393
Product name
4-Bromoaniline
Purity
>99.0%(GC)
Packaging
25g
Price
$28
Updated
2024/03/01
More
Less

4-Bromoaniline Chemical Properties,Usage,Production

Chemical Properties

Gray-brown crystals with a peculiar odor. When heated or burned, they break down and release harmful fumes that contain hydrogen bromide and nitrogen oxides. When dissolved in water, it acts as a mild base. It reacts with acids and powerful oxidizing agents. The compound 4-bromoaniline consists of a hydrophobic benzene ring and an amino group that assists in carrying substances and improving PSC stability.

Uses

4-Bromoaniline is a brominated aniline that is commonly used as a building block in the preparation of pharmaceutical and organic compounds. It is used in the preparation of azo dyes and is condensed with formaldehyde to prepare dihydroquinazolines. In addition, 4-Bromoaniline is also used as an intermediate in the production of other chemicals such as metobromuron, a herbicide, and resorantel, an antiparasitic agent.

Preparation

4-bromoaniline can be made by reacting aniline with bromine with a protection with acetyl chloride.

Synthesis Reference(s)

The Journal of Organic Chemistry, 40, p. 1867, 1975 DOI: 10.1021/jo00900a053
Synthetic Communications, 19, p. 3047, 1989 DOI: 10.1080/00397918908052699

General Description

P-bromoaniline is a brown solid with a sweet odor. (NTP, 1992)

Air & Water Reactions

4-Bromoaniline is sensitive to prolonged exposure to air. Vapor may form highly reactive mixtures in air . Insoluble in water.

Reactivity Profile

Vapor may form highly reactive mixtures in air.

Fire Hazard

Flash point data are not available for 4-Bromoaniline, but 4-Bromoaniline is probably combustible.

Synthesis

RGO/Cu NPs (25 mg), arylboronic acid (1.0 mmol), K2CO3(1.3 mmol), 25-28% aqueous ammonia (5 mmol) and methanol(4 mL) were added to a 50 mL round-bottomed flask. The reactionmixture was stirred under reflux conditions for the appropriatetime. After completion of the reaction as monitored by TLC, themixture was filtered, and the solvent of the filtrate was removedunder vacuum with the aid of a rotary evaporator. The residue waspurified by column chromatography on silica gel to afford 4-Bromoaniline.

Purification Methods

Crystallise the aniline (with appreciable loss) from aqueous EtOH. The benzoyl derivative has m 204o (from EtOH). [Beilstein 12 IV 1497.]

4-Bromoaniline Preparation Products And Raw materials

Raw materials

4-Nitroaniline

Preparation Products

4-BROMO-2-NITROPHENYLBORONIC ACID 6-bromoquinolin-4(3H)-one polyaniline synthesized by means of condensation polymerization 6-Bromoquinoline 4-Bromobiphenyl 6-BROMO-4-CHLOROQUINOLINE 4-(4-Methylpiperazin-1-yl)phenylboronic Acid 4-BROMOPHENYLUREA 4-Aminophenylboronic acid pinacol ester 4'-Bromoacetanilide 4-Aminobiphenyl 2-(4-BROMOPHENYL)THIOPHENE 2-Amino-6-bromobenzothiazole brotianide 5-(4-Bromophenyl)furfural 4-BROMOPHENYLTHIOUREA
More
Less

4-Bromoaniline Suppliers

Americas 1 Belgium 1 Canada 6 China 341 Cyprus 1 Czech Republic 1 Europe 6 France 2 Germany 8 India 80 Japan 9 Russia 2 Slovakia 1 South Korea 2 Switzerland 3 The Netherlands 2 Ukraine 3 United Kingdom 21 United States 58 Global 548
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
AccuStandard Inc
Tel
--
Fax
--
Email
info@bester.nl
Country
United States
ProdList
5300
Advantage
76
BromOrganics Corporation
Tel
--
Fax
--
Email
sales@bromorganics.com
Country
United States
ProdList
1065
Advantage
58
ViTrax, Inc.
Tel
--
Fax
--
Email
info@vitrax.com
Country
United States
ProdList
69
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Spectrum Chemical Mfg. Corp.
Tel
--
Fax
--
Email
marketing@spectrumchemical.com
Country
United States
ProdList
3113
Advantage
60
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Morre-Tec Industries, Inc.
Tel
--
Fax
--
Email
sales@morretec.com
Country
United States
ProdList
169
Advantage
64
Anisyn, Inc.
Tel
--
Fax
--
Email
sales@anisyn.com
Country
United States
ProdList
863
Advantage
0
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
srlmarketing@dishnetdsl.net
Country
United States
ProdList
1905
Advantage
64
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Parish Chemical Company
Tel
--
Fax
--
Country
United States
ProdList
1248
Advantage
47
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
Narchem Corporation
Tel
--
Fax
--
Email
sales@narchem.com
Country
United States
ProdList
2813
Advantage
60
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Boron Molecular Inc.
Tel
--
Fax
--
Email
sales@boronmolecular-usa.com
Country
United States
ProdList
996
Advantage
65
Leonid Chemicals Private Limited
Tel
--
Fax
--
Email
careers@leonidchemicals.com
Country
United States
ProdList
1700
Advantage
43
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
Naugra Export
Tel
--
Fax
--
Country
United States
ProdList
1332
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
SKC Inc.
Tel
--
Fax
--
Email
skcorder@skcinc.com
Country
United States
ProdList
1378
Advantage
76
Wintersun Chemical
Tel
--
Fax
--
Email
purchasing@wintersunchem.com
Country
United States
ProdList
776
Advantage
68
M/S PANAMIT INTERNATIONAL
Tel
--
Fax
--
Email
sales@jyotichem.com
Country
United States
ProdList
312
Advantage
46
R. K. Associate
Tel
--
Fax
--
Country
United States
ProdList
194
Advantage
30
Sciencelab.com, Inc.
Tel
--
Fax
--
Email
accounting@sciencelab.com
Country
United States
ProdList
4159
Advantage
82
J.P.Pharma-Chem Industries
Tel
--
Fax
--
Email
jpi@vsnl.com
Country
United States
ProdList
40
Advantage
52
Loba Chemie Pvt. Ltd.
Tel
--
Fax
--
Country
United States
ProdList
1945
Advantage
71
Kiran Light Laboratories
Tel
--
Fax
--
Country
United States
ProdList
863
Advantage
43
NILE CHEMICALS
Tel
--
Fax
--
Email
nilechem@vsnl.net
Country
United States
ProdList
1369
Advantage
61
American Custom Chemicals Corporation
Tel
--
Fax
--
Email
sales@acccorporation.com
Country
United States
ProdList
6820
Advantage
51
Eastern Chemical Corp.
Tel
--
Fax
--
Email
eastern@u-g.com
Country
United States
ProdList
2786
Advantage
34
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Esprit Chemical Company
Tel
--
Fax
--
Email
admin@esprixtech.com
Country
United States
ProdList
1616
Advantage
55
More
Less

View Lastest Price from 4-Bromoaniline manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
4-Bromoaniline 106-40-1
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21
Hebei Yanxi Chemical Co., Ltd.
Product
4-Bromoaniline 106-40-1
Price
US $20.00-8.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-11-02
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Bromoaniline 106-40-1
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-15

106-40-1, 4-BromoanilineRelated Search:

N,N-Dimethylaniline 4-Amino-benzenesulfonic acid monosodium salt 4-Aminophenylacetic acid 4-Chloroaniline Aniline Sulfanilic acid 4-Fluoroaniline POLYANILINE N-Methylaniline p-Anisidine p-Toluidine 2-BENZOYLACETANILIDE Bromobenzene Diphenylamine Sulfanilamide 4-Aminobenzoic acid 2-Bromo-4,6-dinitroaniline 4-Dimethylaminobenzaldehyde

  • 4-Bromanilinu
  • 4-bromanilinu(czech)
  • 4-bromo-benzenamin
  • AKOS BBS-00003662
  • 4-BROMOBENZENAMIDE
  • 4-BROMOBENZENAMINE
  • 4-BROMOANILINE
  • 4-Bromoanilines
  • 4-BROMOANILINE PESTANAL
  • 4BromoAnilineForSynthesis
  • 4-BromoAnilineForSynthesis-(P-BromoAniline)
  • 4-Bromoaniline96%
  • 4-Bromoaniline,~98%
  • 4-BROMOANILINE SPECIAL QUALITY
  • 4-Bromoaniline, 99+%
  • 4-Bromoaniline, pract., 96%
  • PARA- BROMOANILINE
  • P-BROMOANILINE
  • p-Bromoaniline 4-Bromoaniline
  • p-bromophenylamine
  • ThebroMine aniline
  • 4-BroMoaniline,97%
  • 4-Bromoaniline >=99.0% (GC)
  • 4-Bromoaniline 97%
  • bromoaniline
  • p-bromo-anilin
  • 1-AMINO-4-BROMO-BENZENE
  • BROMOANILINE(4-)
  • 4-BroMoaniline, 99+% 100GR
  • 4-BroMoaniline, 99+% 25GR
  • 4-BroMo-phenylaMine
  • 4-BROMOANILINE GR FOR ANALYSIS
  • 4-BROMOANILINE FOR SYNTHESIS 100 G
  • 4-bromoaniline (SM-2)
  • p-BROMOANILINE pure
  • 4-Aminophenyl bromide
  • 1.4-Bromoaniline
  • 4-BROMO ANILINE , (p-bromophenylamine)
  • 4-Bromoaniline,96%,pract.
  • 4-Bromoaniline, extra pure
  • 4-bromobenzeneamine
  • Aniline, p-bromo-
  • Benzenamine, 4-bromo-
  • Benzenamine,4-bromo-
  • benzenamine,-bromo-
  • 4-BromoaniL
  • 4-Bromoaniline &gt
  • 4-Bromoaniline ISO 9001：2015 REACH
  • 4-Bromoaniline 106-40-1
  • 4-bromoanline
  • 4-Bromoaniline, ≥ 99.0%
  • (2-Bromo-5-methoxy-47-methyl-phenyl)-methano
  • (2-Bromo-5-methoxy-47-methyl-phenyl)-methano
  • PARA BROMO ANILINE (4BA)
  • 4-Bromo Aniline 98% For Synthesis
  • p-Bromoaniline Solution in Toluene
  • 4-Bromoaniline 100 μg/ml Methanol
  • 106-40-1