Fmoc-D-proline

Product Name: Fmoc-D-proline
CAS No.: 101555-62-8
Chemical Name: Fmoc-D-proline
Synonyms: FMOC-D-PRO-OH;FMOC-D-;FMOC-D-PRO;Fmoc-D-proL;FMOC-D-PROLINE;CAS:101555-62-8;n-fmoc-d-proline;FMOC-D-PRO-OH H2O;FMOC-D-PYRD(2)-OH;Fmoc-D-Pro-OH 98%
CBNumber: CB9773220
Molecular Formula: C20H19NO4
Formula Weight: 337.37
MOL File: 101555-62-8.mol

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Fmoc-D-proline Property

Melting point:: 110-116°C
Boiling point:: 548.6±43.0 °C(Predicted)
Density: 1.328±0.06 g/cm3(Predicted)
refractive index: 32 ° (C=1, DMF)
storage temp.: 2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka: 3.95±0.20(Predicted)
form: powder to crystal
color: White to Light yellow
optical activity: [α]/D +31.0±3.0°, c = 1 in DMF
BRN: 5856698
Major Application: peptide synthesis
InChI: InChI=1S/C20H19NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,22,23)/t18-/m1/s1
InChIKey: ZPGDWQNBZYOZTI-GOSISDBHSA-N
SMILES: N1(C(OCC2C3=C(C=CC=C3)C3=C2C=CC=C3)=O)CCC[C@@H]1C(O)=O
CAS DataBase Reference: 101555-62-8(CAS DataBase Reference)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
HS Code: 2933 99 80
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.52149
Product name: Fmoc-D-Pro-OH
Purity: Novabiochem?
Packaging: 5G
Price: $68
Updated: 2026/03/19

Sigma-Aldrich

Product number: 8.52149
Product name: Fmoc-D-Pro-OH
Purity: Novabiochem?
Packaging: 25g
Price: $251
Updated: 2026/03/19

Sigma-Aldrich

Product number: 8.52149
Product name: Fmoc-D-Pro-OH
Purity: Novabiochem<SUP>®</SUP>
Packaging: 1 kg
Price: $8740
Updated: 2026/03/19

Sigma-Aldrich

Product number: 47532
Product name: Fmoc-D-Pro-OH
Purity: ≥99% (GC)
Packaging: 5g
Price: $143
Updated: 2026/03/19

Sigma-Aldrich

Product number: 8.52149
Product name: Fmoc-D-Pro-OH
Purity: Novabiochem<SUP>®</SUP>
Packaging: 100 g
Price: $979
Updated: 2025/07/31

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Fmoc-D-proline Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

In organic synthesis, N-Fmoc-D-proline are often employed as important intermediates in various areas such as peptide synthesis, asymmetric synthesis, medicinal chemistry, and polymer chemistry.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Synthesis

D-proline was added to a round-bottomed flask, 10% aqueous sodium carbonate was added and stirred to dissolve, then dioxane was added, and a 10% dioxane solution of 9-fluorenylmethoxycarbonyl chloride was slowly added dropwise into the reaction solution under an ice bath, and after the dropwise addition was completed the reaction was carried out in an ice bath for 2 hours, and then at room temperature for 8 hours, and the reaction was diluted with the addition of water, and the extract was carried out with ether 4 times, the aqueous layer was placed in an ice bath, the pH was adjusted with concentrated hydrochloric acid until the Congo red paper showed blue, placed in a refrigerator overnight, the white precipitate was extracted with ethyl acetate, the combined organic solution was washed with water, the organic layer was dried with anhydrous magnesium sulphate, and the product FMOC-D-proline was obtained by pumping dry.

Fmoc-D-proline Preparation Products And Raw materials

Raw materials

Preparation Products

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Fmoc-D-proline Suppliers

Americas 1 Canada 1 China 260 Europe 4 France 1 Germany 6 India 22 Japan 6 South Korea 1 Switzerland 6 United Kingdom 8 United States 45 Global 361

Shanghai Jifeng Biotechnology Co., Ltd.

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View Lastest Price from Fmoc-D-proline manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Fmoc-D-Pro-OH.H2OFmoc-D-Pro 101555-62-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-12-13

Career Henan Chemical Co

Product: Fmoc-D-proline 101555-62-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-15

Career Henan Chemical Co

Product: Fmoc-D-proline 101555-62-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-15

101555-62-8, Fmoc-D-prolineRelated Search:

D-Proline Nalpha-Fmoc-Ndelta-trityl-L-glutamine L-Fmoc-Aspartic acid alpha-tert-butyl ester 9-Fluorenemethanol Fmoc-Asp(OtBu)-OH L-PROLINE-(4-3H(N)) Fmoc-Lys(Boc)-OH 9-Fluorenylmethyl chloroformate L-Proline Fmoc-Phe-OH METHOXYCARBONYLSULFENYL CHLORIDE cis-4-Hydroxy-L-proline Fmoc-Met-OH Fmoc-D-phenylalanine Fmoc-OSu FMOC-THR(TBU)-OL FMOC-5-AMINOPENTANOIC ACID Fmoc-D-Asn(Trt)-OH

(R)-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-(9H-FLUOREN-9-YLMETHYL) ESTER

N-ALPHA-FMOC-D-PROLINE

N-(9-FLUORENYLMETHOXYCARBONYL)-D-PROLINE

N-(9-FLUORENYLMETHOXYCARBONYL)-D-PYRROLIDINE-2-CARBOXYLIC ACID

N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-PROLINE

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-PROLINE

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-D-PROLINE MONOHYDRATE

9-FLUORENYLMETHOXYCARBONYL-D-PROLINE

FMOC-D-PRO

FMOC-D-PROLINE

FMOC-D-PRO-OH

FMOC-D-PRO-OH H2O

FMOC-D-PYRD(2)-OH

n-[(9h-fluoren-9-ylmethoxy)carbonyl]-d-proline

n-fmoc-d-proline

FMOC-D-

(R)-PYRROLIDINE-1,2-DICARBOXYLIC ACID

1-(9H-FLUOREN-9-YLMETHYL) ESTER

N-Fmoc-D-proline, 98+%, may cont. up to ca 5% water

FMOC-D-PROLINE extrapure

Nα-(9-Fluorenylmethyloxycarbonyl)-D-proline monohydrate ,99%

Fmoc-D-proline ,99%

FMoc-D-Pro-OH ,99%

FMoc-D-Pro-OH FMoc-D-Proline

N-Fmoc-D-proline Fmoc-D-Pro-OH

D-Proline-d3-N-FMOC

(R)-Fmoc-pyrrolidine-2-carboxylic acid

Fmoc-D-proline≥ 99.9% (HPLC, Chiral purity)

(9H-Fluoren-9-yl)MethOxy]Carbonyl D-Pro-OH

Fmoc-D-Pro-OH >=98.0%

(R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)pyrrolidine-2-carboxylicacid

(2R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}pyrrolidine-2-carboxylic acid

1,2-Pyrrolidinedicarboxylicacid, 1-(9H-fluoren-9-ylmethyl) ester, (2R)-

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-proline&gt

Fmoc-D-proline,98%

Fmoc-D-proL

Fmoc-D-proline USP/EP/BP

Fmoc-D-proline 101555-62-8 99.0%

Fmoc-D-Pro-OH.H2O Fmoc-D-Pro

Fmoc-D-Pro-OH (D-isomer)

CAS:101555-62-8

Fmoc-<sc>D</sc>-Pro-OH

Fmoc-D-Prolinemonohydrate

Fmoc-D-Pro-OH 98%

101555-62-8

1O1555-62-8

C20HNO4

Specialty Synthesis

Peptide Synthesis

Amino Acid Derivatives

Amino Acids (N-Protected)

Biochemistry

Fmoc-Amino Acids

Fmoc-Amino acid series

Proline [Pro, P]

Fmoc-Amino Acids and Derivatives

Amino Acids