AC-LEU-GLU-HIS-ASP-AMC

Product Name: AC-LEU-GLU-HIS-ASP-AMC
CAS No.: 292633-16-0
Chemical Name: AC-LEU-GLU-HIS-ASP-AMC
Synonyms: AC-LEHD-AMC;AC-LEHD-MCA;PASE-9SUBSTRATE;AC-LEU-GLU-HIS-ASP-MCA;AC-LEU-GLU-HIS-ASP-AMC;CASPASE-9 SUBSTRATE (FLUOROGENIC);AC-LEHD-AMC TRIFLUOROACETATE SALT;CASPASE-9 SUBSTRATE ;AC-LEU-GLU-HIS-ASP-AMC;AC-LEU-GLU-HIS-ASP-7-AMINO-4-METHYLCOUMARIN;AC-LEU-GLU-HIS-ASP-AMC TRIFLUOROACETATE SALT
CBNumber: CB9777859
Molecular Formula: C33H41N7O11
Formula Weight: 711.72
MOL File: 292633-16-0.mol

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AC-LEU-GLU-HIS-ASP-AMC Property

Boiling point:: 1258.1±65.0 °C(Predicted)
Density: 1.388±0.06 g/cm3(Predicted)
storage temp.: -15°C
solubility: Water: 1 mg/ml
form: Lyophilized Powder
pka: 4.07±0.10(Predicted)
color: White to off-white
Water Solubility: 1mg/mL in water

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 24569
Product name: Ac-LEHD-AMC (trifluoroacetate salt)
Purity: ≥95%
Packaging: 500μg
Price: $31
Updated: 2024/03/01

Cayman Chemical

Product number: 24569
Product name: Ac-LEHD-AMC (trifluoroacetate salt)
Purity: ≥95%
Packaging: 1mg
Price: $59
Updated: 2024/03/01

Cayman Chemical

Product number: 24569
Product name: Ac-LEHD-AMC (trifluoroacetate salt)
Purity: ≥95%
Packaging: 5mg
Price: $177
Updated: 2024/03/01

Biosynth Carbosynth

Product number: FA110585
Product name: Ac-Leu-Glu-His-Asp-AMC trifluoroacetate salt
Packaging: 1mg
Price: $91
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA110585
Product name: Ac-Leu-Glu-His-Asp-AMC trifluoroacetate salt
Packaging: 2mg
Price: $158
Updated: 2021/12/16

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AC-LEU-GLU-HIS-ASP-AMC Chemical Properties,Usage,Production

Description

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9. Ac-LEHD-AMC is cleaved by caspase-9 to release the fluorescent moiety AMC, which can be used to quantify caspase-9 activity.

Uses

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9 (Excitation: 341 nm; Emission: 441 nm). Caspase-9 can induce hydrolysis of Ac-LEHD-AMC, resulting in the release of AMC fluorophore and its fluorescence can be used to quantify caspase-9 activity[1].

References

[1] Igor M Prudnikov, et al. Short peptide tools for monitoring caspase and proteasome activities in embryonal and adult rat brain lysates: an approach for the differential identification of proteases. J Biochem. 2012 Mar;151(3):299-316. DOI:10.1093/jb/mvs001

Sequene

Ac-Leu-Glu-His-Asp-AMC

AC-LEU-GLU-HIS-ASP-AMC Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-LEU-GLU-HIS-ASP-AMC Suppliers

China 50 France 1 Japan 1 Switzerland 1 United Kingdom 3 United States 5 Global 61

GL Biochem (Shanghai) Ltd

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Nanjing Leon Biological Technology Co., Ltd.

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Nanjing Peptide Biotech Ltd.

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Career Henan Chemica Co

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292633-16-0, AC-LEU-GLU-HIS-ASP-AMCRelated Search:

AC-VDVAD-PNA Z-VAD-FMK AC-YVAD-PNA CASPASE INHIBITOR3 AC-VEID-AMC Z-ASP-2,6-DICHLOROBENZOYLOXYMETHYLKETONE Z-YVAD-AFC ALPHA-(TRICHLOROMETHYL)-4-PYRIDINEETHANOL AC-VDVAD-CHO AC-DEVD-AFC PAC1 AC-DEVD-CHO AC-LEU-GLU-THR-ASP-AFC AC-LEHD-AFC AC-LEU-GLU-HIS-ASP-AMC AC-LEU-GLU-THR-ASP-AMC AC-LEU-GLU-VAL-ASP-AMC AC-LEU-GLU-HIS-ASP-AMC TFA SALT

N-ACETYL-LEU-GLU-HIS-ASP-7-AMINO-4-METHYLCOUMARIN AMC

CASPASE-9 SUBSTRATE (FLUOROGENIC)

ACETYL-L-LEUCYL-L-GLUTAMYL-L-HISTIDYL-L-ASPARTIC ACID ALPHA-(4-METHYLCOUMARYL-7-AMIDE)

AC-LEHD-MCA

AC-LEHD-AMC

AC-LEHD-AMC TRIFLUOROACETATE SALT

AC-LEU-GLU-HIS-ASP-7-AMINO-4-METHYLCOUMARIN

AC-LEU-GLU-HIS-ASP-AMC

AC-LEU-GLU-HIS-ASP-AMC TRIFLUOROACETATE SALT

AC-LEU-GLU-HIS-ASP-MCA

CASPASE-9 SUBSTRATE ;AC-LEU-GLU-HIS-ASP-AMC

N-Acetyl-Leu-Glu-His-Asp-7-amino-4-methylcoumarin

L-α-Asparagine, N-acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-

N-Acetyl-L-leucyl-L-α-glutamyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine

PASE-9SUBSTRATE

292633-16-0

C33H41N7O11

peptide

Pepetides