Description
ChemicalBook > CAS DataBase List > Scopine-2,2-dithienyl glycolate

Scopine-2,2-dithienyl glycolate

Description
Product Name
Scopine-2,2-dithienyl glycolate
CAS No.
136310-64-0
Chemical Name
Scopine-2,2-dithienyl glycolate
Synonyms
N-DeMethyl TiotropiuM;N-Desmethyl Tiotropium;Tiotropium EP Impurity B;SCOPINE-2,2-DITHIENYL GLYCOLATE;Tiotropium Bromide EP Impurity B;Scopolamine 2-(2-thienyl)glycolate;CO base bis (2-thiophenyl) glycolate;Scopolamine 2- (2-thiophenyl) glycolate;Scopine-2,2-dithienyl glycolate USP/EP/BP;Tiotropium Bromide Monohydrate Impurity B
CBNumber
CB9843604
Molecular Formula
C18H19NO4S2
Formula Weight
377.48
MOL File
136310-64-0.mol
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Scopine-2,2-dithienyl glycolate Property

Melting point:
138-140°C
Boiling point:
542.3±50.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
10.32±0.29(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
S199965
Product name
ScopineDi(2-thienylglycolate)
Packaging
10mg
Price
$175
Updated
2021/12/16
Matrix Scientific
Product number
090317
Product name
Scopine di(2-thienyl)glycolate
Purity
95+%
Packaging
250mg
Price
$378
Updated
2021/12/16
Biosynth Carbosynth
Product number
IS145668
Product name
Scopine-2,2-dithienyl glycolate
Packaging
1g
Price
$525
Updated
2021/12/16
AK Scientific
Product number
I986
Product name
Scopine-2,2-dithienylglycolate
Packaging
1g
Price
$551
Updated
2021/12/16
Biosynth Carbosynth
Product number
IS145668
Product name
Scopine-2,2-dithienyl glycolate
Packaging
2g
Price
$630
Updated
2021/12/16
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Scopine-2,2-dithienyl glycolate Chemical Properties,Usage,Production

Description

Scopine-2,2-dithienyl glycolate is an organic compound. It is off-white solid. The melting point is 138-140°C. The storage temperature is -20°C. Scopine-2,2-dithienyl glycolate is one of the reaction intermediates in the preparation of tiotropium bromide, which is a highly effective anticholinergic agent and widely used for treatment of asthma and/or chronic obstructive pulmonary disease (COPD) (chronic obstructive pulmonary disease).

Chemical Properties

Off-White Solid

Uses

Scopine Di(2-thienylglycolate) (Tiotropium EP Impurity B) is a precursor to Tiotropium Bromide.

Scopine-2,2-dithienyl glycolate Preparation Products And Raw materials

Raw materials

Preparation Products

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Scopine-2,2-dithienyl glycolate Suppliers

Canada 2 China 180 Europe 2 Germany 2 India 9 United Kingdom 5 United States 13 Global 213
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View Lastest Price from Scopine-2,2-dithienyl glycolate manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Scopine-2,2-dithienyl glycolate 136310-64-0
Price
US $85.00-850.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-07
R&D Scientific Inc.
Product
Scopine-2,2-dithienyl glycolate 136310-64-0
Price
US $480.00/g
Min. Order
1g
Purity
98
Supply Ability
500 Kg
Release date
2024-04-24
Wuhan Xinhao Biotechnology Co., Ltd
Product
Scopine Di(2-thienyl) Glycolate 136310-64-0
Price
US $10.00-100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 MT/Month
Release date
2024-03-11

136310-64-0, Scopine-2,2-dithienyl glycolateRelated Search:

Methyl glycolate (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Tetrahydrothiophene 2-Thiopheneethanol Starch, hydrogen phosphate, 2-hydroxypropyl ether 2-Diethylaminoethyl hexanoate Tiotropium bromide Methyl 2,2-dithienylglycolate BIS(2-THIENYL) KETONE 4-Benzyl Albuterol [R(R*,R*]-2-amino-1-[p-(methylsulphonyl)phenyl]propane-1,3-diol Tiotropium bromide Impurity 16 (1α,2β,4β,5α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7α-ol 2,3-Dibromothiophene Teloidine Ethanedioic acid,1-methyl ester, potassium salt (1:1) TiotropiuM BroMide IMpurity I Scopine Methobromide

  • SCOPINE-2,2-DITHIENYL GLYCOLATE
  • (1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 2-hydroxy-2,2-dithiophen-2-ylacetate
  • Tiotropium EP Impurity B
  • 2-Thiopheneacetic acid, -hydroxy--2-thienyl-, (1,2,4,5,7)
  • 2-thiopheneacetic acid, a-hydroxy-a-2th ( Di(2-thienyl) Glycolate )
  • N-DeMethyl TiotropiuM
  • α-Hydroxy-α-2-thienyl-2-thiopheneacetic Acid (1α,2β,4β,5α,7β)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl Ester
  • Scopine di(2-thienyl)glycolate scopine-2-dithienyl glycolate
  • Tiotropium Bromide Impurity 2(Tiotropium Bromide EP Impurity B)
  • Tiotropium Bromide EP Impurity B
  • 2-Thiopheneacetic acid, α-hydroxy-α-2-thienyl-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester
  • CO base bis (2-thiophenyl) glycolate
  • Scopine-2,2-dithienyl glycolate USP/EP/BP
  • Scopolamine 2-(2-thienyl)glycolate
  • High purity CAS 136310-64-0 Scopine-2,2-dithienyl glycolate in stock
  • N-Desmethyl Tiotropium
  • rel-(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl 2-hydroxy-2,2-di(thiophen-2-yl)acetate
  • Tiotropium Bromide Monohydrate EP Impurity B
  • Tiotropium Bromide Monohydrate Impurity B
  • Scopolamine 2- (2-thiophenyl) glycolate
  • Scopine di (2-thienyl) glycolate Intermediate
  • 136310-64-0
  • C18H19NO4S2
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Tiotropium Bromide Intermediates
  • TIOTROPIUM BROMIDE
  • 136310-64-0