3-Hydroxyphenylacetylene

Product Name: 3-Hydroxyphenylacetylene
CAS No.: 10401-11-3
Chemical Name: 3-Hydroxyphenylacetylene
Synonyms: 3-ETHYNYLPHENOL;4-ETHYNYL-PHENOL;Phenol, 3-ethynyl-;TIMTEC-BB SBB005886;3-HYDROXYPHENYLACETYLENE;Phenol, 3-ethynyl- (9CI);M-HYDROXYPHENYLACETYLENE;3-HYDROXYPHENYLACETYLENE, 95+%;3-Hydroxyphenylacetylene >=95.0%;3-HYDROXYPHENYLACETYLENE (3-Ethynylphenol)
CBNumber: CB9852635
Molecular Formula: C8H6O
Formula Weight: 118.13
MOL File: 10401-11-3.mol

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3-Hydroxyphenylacetylene Property

Melting point:: 64-66 °C
Boiling point:: 75°C 3mm
Density: 1.083 g/mL at 25 °C(lit.)
refractive index: n20/D 1.5840(lit.)
Flash point:: 218 °F
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Miscible with dimethylformamide.
pka: 9.30±0.10(Predicted)
form: Crystalline Powder
color: White to pale yellow
BRN: 2076613
InChI: InChI=1S/C8H6O/c1-2-7-4-3-5-8(9)6-7/h1,3-6,9H
InChIKey: AODMJIOEGCBUQL-UHFFFAOYSA-N
SMILES: C1(O)=CC=CC(C#C)=C1
CAS DataBase Reference: 10401-11-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22-41-52/53
Safety Statements: 26-37/39
RIDADR: 2810
WGK Germany: 2
HazardClass: 8
PackingGroup: Ⅲ
HS Code: 29071990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 632023
Product name: 3-Hydroxyphenylacetylene
Purity: ≥95.0%
Packaging: 1g
Price: $66.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 632023
Product name: 3-Hydroxyphenylacetylene
Purity: ≥95.0%
Packaging: 5g
Price: $271
Updated: 2025/07/31

TCI Chemical

Product number: E1421
Product name: 3-Ethynylphenol
Purity: min. 98.0 %
Packaging: 1G
Price: $277
Updated: 2025/07/31

GFS CHEMICALS

Product number: 81992
Product name: 3-ETHYNYLPHENOL,95%
Packaging: 10g
Price: $777.23
Updated: 2021/12/16

TRC

Product number: E938110
Product name: 3-Ethynylphenol
Packaging: 100mg
Price: $65
Updated: 2021/12/16

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3-Hydroxyphenylacetylene Chemical Properties,Usage,Production

Chemical Properties

Clear yellow liquid

Uses

3-Hydroxyphenylacetylene is used as a fluorogenic and chromogenic probe for bacterial enzymes.

Synthesis

388061-72-1

10401-11-3

The general procedure for the synthesis of 3-hydroxyphenylacetylene from (3-hydroxyphenylalkynyl)trimethylsilane was as follows: (3-hydroxyphenylalkynyl)trimethylsilane was dissolved in a mixed solvent of THF (6 mL) and MeOH (6 mL), followed by the addition of 10% aqueous KOH solution (6 mL). The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction mixture was neutralized with 1N HCl solution and the solvent was subsequently removed by rotary evaporation. The aqueous phase was extracted with CH2Cl2 and the organic phase was dried with anhydrous Na2SO4. Finally, purification by column chromatography (eluent: n-hexane/acetone, 5:1, v/v) afforded 3-hydroxyphenylacetylene (162.8 mg, 70% yield), the product was a yellow oil.

References

[1] Patent: US2009/68242, 2009, A1. Location in patent: Page/Page column 7
[2] Organic Letters, 2014, vol. 16, # 24, p. 6302 - 6305

3-Hydroxyphenylacetylene Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Hydroxyphenylacetylene Suppliers

Americas 1 Belgium 1 Canada 2 China 130 Europe 3 Germany 3 India 12 Japan 1 Switzerland 3 United Kingdom 4 United States 27 Global 187

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View Lastest Price from 3-Hydroxyphenylacetylene manufacturers

Career Henan Chemical Co

Product: 3-Hydroxyphenylacetylene 10401-11-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-09

10401-11-3, 3-HydroxyphenylacetyleneRelated Search:

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3-HYDROXYPHENYLACETYLENE (3-Ethynylphenol)

Phenol, 3-ethynyl- (9CI)

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M-HYDROXYPHENYLACETYLENE

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3-Ethynylphenol 3-Hydroxyphenylacetylene

3-Hydroxyphenylacetylene >=95.0%

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10401-11-3

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