2-Nitrobenzoic acid
- Product Name
- 2-Nitrobenzoic acid
- CAS No.
- 552-16-9
- Chemical Name
- 2-Nitrobenzoic acid
- Synonyms
- O-NITROBENZOIC ACID;2-nitrobenzoic;2-NITRODRACYLIC ACID;2-Nitrobenzoicacid,95%;Nitrobenzoic aci;2-nitro-benzoicaci;o-Nitrobenaoicacid;o-nitro-benzoicaci;RARECHEM AL BO 0202;ORTHO-NITROBENZOATE
- CBNumber
- CB9853809
- Molecular Formula
- C7H5NO4
- Formula Weight
- 167.12
- MOL File
- 552-16-9.mol
2-Nitrobenzoic acid Property
- Melting point:
- 146-148 °C(lit.)
- Boiling point:
- 295.67°C (rough estimate)
- Density
- 1,58 g/cm3
- refractive index
- 1.6280 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 7.8g/l
- form
- Fine Powder
- pka
- 2.16(at 18℃)
- color
- Off-white
- Specific Gravity
- 1.58
- Water Solubility
- 6.8 g/L
- Merck
- 14,6588
- BRN
- 1910632
- Stability:
- Stable. Incompatible with strong oxidizing agents, strong bases.
- CAS DataBase Reference
- 552-16-9(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzoic acid, 2-nitro-(552-16-9)
- EPA Substance Registry System
- o-Nitrobenzoic acid (552-16-9)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-68-22
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- RTECS
- DH5050000
- TSCA
- Yes
- HS Code
- 29163900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 127698
- Product name
- 2-Nitrobenzoic acid
- Purity
- 95%, Contains 3- and 4-isomers
- Packaging
- 5g
- Price
- $51.1
- Updated
- 2024/03/01
- Product number
- 127698
- Product name
- 2-Nitrobenzoic acid
- Purity
- 95%, Contains 3- and 4-isomers
- Packaging
- 100g
- Price
- $155
- Updated
- 2024/03/01
- Product number
- N0155
- Product name
- 2-Nitrobenzoic Acid
- Purity
- >90.0%(GC)
- Packaging
- 25g
- Price
- $44
- Updated
- 2024/03/01
- Product number
- N0155
- Product name
- 2-Nitrobenzoic Acid
- Purity
- >90.0%(GC)
- Packaging
- 500g
- Price
- $460
- Updated
- 2024/03/01
- Product number
- A10393
- Product name
- 2-Nitrobenzoic acid, 95%
- Packaging
- 100g
- Price
- $36.65
- Updated
- 2024/03/01
2-Nitrobenzoic acid Chemical Properties,Usage,Production
Chemical Properties
off-white powder
Uses
NH2-protecting reagent.
Uses
2-Nitrobenzoic Acid is used as a reagent in the synthesis of several organic compounds including that of novel triazoles and a tetrazole of escitalopram which act as cholinesterase inhibitors. It is also used in the one pot synthesis of 1,4-disubstituted 1,2,3-triazoles.
Definition
ChEBI: A nitrobenzoic acid carrying the nitro substituent at position 2.
Synthesis Reference(s)
The Journal of Organic Chemistry, 56, p. 5924, 1991 DOI: 10.1021/jo00020a040
Tetrahedron Letters, 35, p. 219, 1994 DOI: 10.1016/S0040-4039(00)76515-4
General Description
Yellowish white crystals with an intensely sweet taste.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Nitrobenzoic acid is incompatible with strong oxidizing agents. Also incompatible with strong bases. May react with cyanides .
Health Hazard
ACUTE/CHRONIC HAZARDS: When 2-Nitrobenzoic acid is heated to decomposition it emits very toxic fumes.
Fire Hazard
Flash point data concerning 2-Nitrobenzoic acid are not available, however, 2-Nitrobenzoic acid is probably combustible.
Purification Methods
Crystallise the acid from *benzene (twice), n-butyl ether (twice), then water (twice). Dry and store it in a vacuum desiccator. [Le Noble & Wheland J Am Chem Soc 80 5397 1958.] It has also been crystallised from EtOH/H2O. The amide has m 176.5o (from H2O). [Beilstein 9 III 1466, 9 IV 1046.]
2-Nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-Nitrobenzoic acid Suppliers
View Lastest Price from 2-Nitrobenzoic acid manufacturers
- Product
- 2-Nitrobenzoic acid 552-16-9
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25
- Product
- 2-Nitrobenzoic acid 552-16-9
- Price
- US $30.00-10.00/kg
- Min. Order
- 10kg
- Purity
- 99%
- Supply Ability
- 100000kg
- Release date
- 2023-04-13
- Product
- 2-Nitrobenzoic acid 552-16-9
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2022-09-26