4-Bromothiophene-2-carbonitrile

Product Name: 4-Bromothiophene-2-carbonitrile
CAS No.: 18791-99-6
Chemical Name: 4-Bromothiophene-2-carbonitrile
Synonyms: 4-Bromo-2-cyanothiophene;4-Bromo-2-cyanothiophene >4-Bromothiophene-2-carbonitrile;2-Thiophenecarbonitrile,4-broMo-;4-Bromothiophene-2-carbonitrile98%;4-Bromothiophene-2-carbonitrile 98%;4-Bromothiophene-2-carbonitrile ISO 9001：2015 REACH
CBNumber: CB9956384
Molecular Formula: C5H2BrNS
Formula Weight: 188.05
MOL File: 18791-99-6.mol

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4-Bromothiophene-2-carbonitrile Property

Melting point:: 47.0 to 51.0 °C
Boiling point:: 230.4±20.0 °C(Predicted)
Density: 1.82±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
color: White to Light yellow

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B4212
Product name: 4-Bromo-2-cyanothiophene
Purity: >98.0%(GC)
Packaging: 1g
Price: $56
Updated: 2025/07/31

TCI Chemical

Product number: B4212
Product name: 4-Bromo-2-cyanothiophene
Purity: >98.0%(GC)
Packaging: 5g
Price: $205
Updated: 2021/12/16

TRC

Product number: B698978
Product name: 4-Bromothiophene-2-carbonitrile
Packaging: 250mg
Price: $55
Updated: 2021/12/16

Matrix Scientific

Product number: 024617
Product name: 4-Bromothiophene-2-carbonitrile
Purity: 98%
Packaging: 5g
Price: $48
Updated: 2021/12/16

Matrix Scientific

Product number: 024617
Product name: 4-Bromothiophene-2-carbonitrile
Purity: 98%
Packaging: 25g
Price: $168
Updated: 2021/12/16

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4-Bromothiophene-2-carbonitrile Chemical Properties,Usage,Production

Synthesis

18791-75-8

18791-99-6

The general procedure for the synthesis of 4-bromothiophene-2-carbonitrile from 4-bromo-2-thiophenecarboxaldehyde was as follows: 4-bromothiophene-2-carboxaldehyde (600 g, 3.14 mmol) and hydroxylamine hydrochloride (438 g, 6.30 mmol) were dissolved in pyridine (5 L). After the reaction mixture was cooled to room temperature, it was heated to 90 °C and maintained for 10 min. Subsequently, acetic anhydride (1940 g, 19.0 mmol) was slowly added dropwise and the reaction system was heated to 80°C for 1 hour. After completion of the reaction, the mixture was poured into water (20 L) and stirred for 30 min. After filtration and drying, the target product 4-bromothiophene-2-carbonitrile (564 g, 95% yield) was obtained.

References

[1] Patent: CN104230960, 2017, B. Location in patent: Paragraph 0449; 0450; 0451
[2] Bioorganic and Medicinal Chemistry Letters, 2000, vol. 10, # 5, p. 415 - 418
[3] Bioorganic and Medicinal Chemistry Letters, 2005, vol. 15, # 11, p. 2870 - 2875
[4] Patent: US2017/151225, 2017, A1. Location in patent: Paragraph 0926; 0927

4-Bromothiophene-2-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromothiophene-2-carbonitrile Suppliers

Americas 1 Canada 1 China 73 Europe 1 India 2 Japan 1 United Kingdom 1 United States 11 Global 91

TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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9ding chemical ( Shanghai) Limited

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View Lastest Price from 4-Bromothiophene-2-carbonitrile manufacturers

R&D Scientific Inc.

Product: 4-Bromo-2-cyanothiophene 18791-99-6
Price: US $530.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-02-23

Career Henan Chemical Co

Product: 4-Bromothiophene-2-carbonitrile 18791-99-6
Price: US $1.00/KG
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-10

18791-99-6, 4-Bromothiophene-2-carbonitrileRelated Search:

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2-Thiophenecarbonitrile,4-broMo-

4-Bromothiophene-2-carbonitrile98%

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4-Bromothiophene-2-carbonitrile ISO 9001：2015 REACH

18791-99-6

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