5-BROMOTHIOPHENE-2-CARBONITRILE

Product Name: 5-BROMOTHIOPHENE-2-CARBONITRILE
CAS No.: 2160-62-5
Chemical Name: 5-BROMOTHIOPHENE-2-CARBONITRILE
Synonyms: 5-BROMOTHIOPHENE-2-CAR;2-Bromo-5-cyanothiophene;2-Cyano-5-bromothiophene;2-Bromo-5-cyanothiophene>5-BroMothiophene-2-carbon...;5-Bromo-2-Thiophenecarbonitrile;5-BROMOTHIOPHENE-2-CARBONITRILE;5-Bromothiophene-2-acetonitrile;2-Thiophenecarbonitrile,5-broMo-;5-Brono-thiophene-2-carbonitrile
CBNumber: CB3397817
Molecular Formula: C5H2BrNS
Formula Weight: 188.05
MOL File: 2160-62-5.mol

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5-BROMOTHIOPHENE-2-CARBONITRILE Property

Boiling point:: 124°C/34mmHg(lit.)
Density: 1.694 g/mL at 25 °C (lit.)
refractive index: n20/D 1.6190(lit.)
Flash point:: 214 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: clear liquid
color: Colorless to Light orange to Yellow
Specific Gravity: 1.619
λmax: 276nm(Benzene)(lit.)
InChI: InChI=1S/C5H2BrNS/c6-5-2-1-4(3-7)8-5/h1-2H
InChIKey: YVVHCBNJWHPMCQ-UHFFFAOYSA-N
SMILES: C1(C#N)SC(Br)=CC=1

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37
RIDADR: 3267
WGK Germany: 3
HS Code: 29309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 574430
Product name: 5-Bromothiophene-2-carbonitrile
Purity: 97%
Packaging: 1g
Price: $52.08
Updated: 2025/07/31

TCI Chemical

Product number: B4204
Product name: 2-Bromo-5-cyanothiophene
Purity: >97.0%(GC)
Packaging: 1g
Price: $135
Updated: 2023/01/07

TRC

Product number: B698980
Product name: 5-Bromothiophene-2-carbonitrile
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Ark Pharm

Product number: P000265642
Product name: 5-Bromothiophene-2-carbonitrile
Purity: 97%
Packaging: 250mg
Price: $13
Updated: 2021/12/16

Ark Pharm

Product number: P000265642
Product name: 5-Bromothiophene-2-carbonitrile
Purity: 97%
Packaging: 1g
Price: $25
Updated: 2021/12/16

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5-BROMOTHIOPHENE-2-CARBONITRILE Chemical Properties,Usage,Production

Chemical Properties

Colorless liquid or semisolid

Synthesis

2160-63-6

2160-62-5

General procedure for the synthesis of 5-bromothiophene-2-carboxaldehyde oxime from 5-bromothiophene-2-carbonitrile: To a mixture of 5-bromothiophene-2-carboxaldehyde oxime (1.3 g, 6.2 mmol) and tetrahydrofuran (15 mL), acetic acid (1.4 mL, 25 mmol) and acetic anhydride (1.5 mL, 15 mmol) were added, and the reaction was started at room temperature. Subsequently, the reaction mixture was stirred at 50 °C for 2 hours, then warmed to 70 °C to continue stirring for 8 hours. Upon completion of the reaction, the reaction mixture was cooled and the solvent was removed by vacuum concentration. The crude product was purified by NH-silica gel column chromatography (eluent ratio heptane:ethyl acetate=8:1) to afford 5-bromothiophene-2-carbonitrile (1.0 g, 5.4 mmol, 88% yield) as a colorless solid.1H-NMR (CDCl3) δ (ppm): 7.11 (1H, d, J=4.0 Hz), 7.40 (1H, d, J=4.0 Hz).

References

[1] Patent: EP1782811, 2007, A1. Location in patent: Page/Page column 51
[2] Bulletin de la Societe Chimique de France, 1967, p. 4115 - 4120
[3] Patent: WO2003/87103, 2003, A1. Location in patent: Page/Page column 17
[4] Patent: WO2005/82899, 2005, A1. Location in patent: Page/Page column 30
[5] Synlett, 2011, # 15, p. 2223 - 2227

5-BROMOTHIOPHENE-2-CARBONITRILE Preparation Products And Raw materials

Raw materials

1,1'-Carbonyldiimidazole Sodium acetate 2-Thiophenecarboxylic acid Acetic anhydride N,N-Dimethylformamide Bromine Acetic acid

Preparation Products

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5-BROMOTHIOPHENE-2-CARBONITRILE Suppliers

Americas 1 China 150 Europe 1 India 5 Japan 1 Switzerland 1 United Kingdom 1 United States 15 Global 175

Chengdu J&B Technology Co., Ltd.

Tel: 028-61186694 15608078506
Fax: 028-61186694
Email: 609128801@qq.com
Country: China
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Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Energy Chemical

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Fax: 021-58436166
Email: sales8178@energy-chemical.com
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Capot Chemical Co., Ltd

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Accela ChemBio Co.,Ltd.

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Nanjing Chemlin Chemical Co., Ltd

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky（shanghai）International Co.,Ltd.

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Shanghai yirong biology science and technology co., ltd

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Dtchem Laboratories,（Gan Su）Co.,Ltd.

Tel: 18993966060
Fax: 0943-8288977
Email: sales@techbiochem.com
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View Lastest Price from 5-BROMOTHIOPHENE-2-CARBONITRILE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-Bromothiophene-2-carbonitrile 2160-62-5
Price: US $1.10-9.90/KG
Min. Order: 1KG
Purity: 99% min
Supply Ability: 100kg
Release date: 2025-08-18

Shaanxi Dideu New Materials Co. Ltd

Product: 5-BROMOTHIOPHENE-2-CARBONITRILE 2160-62-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-07-06

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMOTHIOPHENE-2-CARBONITRILE 2160-62-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

2160-62-5, 5-BROMOTHIOPHENE-2-CARBONITRILERelated Search:

(5-Bromopyrimidin-4-yl)methanol 2-BROMO-4-CYANOTHIOPHENE 5-FLUORO-2-THIOPHENECARBOXYLIC ACID 2-Chloro-5-thiophenecarboxaldehyde 5-CHLORO-2-THIOPHENECARBONITRILE 5-methylthiophene-2-carbonitrile 5-Bromothiophene-2-carbaldehyde 5-CHLOROTHIOPHENE-2-CARBONYL CHLORIDE 5-Bromo-2-thiophenecarboxylic acid 5-Methylthiophene-2-carboxaldehyde 5-Chloro-2-thiophenecarboxylic Acid 5-Methyl-2-thiophenecarboxylic acid 4-Bromothiophene-2-carbonitrile,4-Bromothiophene-2-carbonitrile 98% 5-BROMOTHIOPHENE-2-CARBONITRILE 2-Bromothiophene-3-carbonitrile,2-Bromothiophene-3-carbonitrile 97% 3-BROMOTHIOPHENE-2-CARBONITRILE 4-BROMOTHIOPHENE-3-CARBONITRILE,3-Bromothiophene-4-carbonitrile 7-BROMO-2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXINE-5-CARBONITRILE

5-Brono-thiophene-2-carbonitrile

5-Bromothiophene-2-carbonitrile ,97%

2-Cyano-5-bromothiophene

5-BroMothiophene-2-carbon...

2-Thiophenecarbonitrile,5-broMo-

2-Bromo-5-cyanothiophene

5-BROMOTHIOPHENE-2-CARBONITRILE

5-Bromo-2-Thiophenecarbonitrile

5-BROMOTHIOPHENE-2-CAR

JR-6693, 5-Bromothiophene-2-carbonitrile, 97%

2-Bromo-5-cyanothiophene&gt

5-Bromothiophene-2-acetonitrile

2160-62-5

Building Blocks

Thiophenes

Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Thiophenes

ThiophenesBuilding Blocks