ChemicalBook > CAS DataBase List > 4-Bromo-1-fluoro-2-iodobenzene
4-Bromo-1-fluoro-2-iodobenzene
- Product Name
- 4-Bromo-1-fluoro-2-iodobenzene
- CAS No.
- 116272-41-4
- Chemical Name
- 4-Bromo-1-fluoro-2-iodobenzene
- Synonyms
- 3-Iodo-4-fluorobromobenzene;5-Bromo-2-fluoroiodobenzene;2-Iodo-4-bromofluorobenzene;2-fluoro-5-bromo-iodobenzene;4-FLUORO-3-IODO BROMOBENZENE;5-Bromo-2-fluoro-1-iodobenzene;4-Bromo-1-fluoro-2-iodobenzene;4-Bromo-1-fluoro-4-iodobenzene;5-Bromo-2-fluoroiodobenzene 99%;Benzene, 4-bromo-1-fluoro-2-iodo-
- CBNumber
- CB9971774
- Molecular Formula
- C6H3BrFI
- Formula Weight
- 300.89
- MOL File
- 116272-41-4.mol
More
Less
4-Bromo-1-fluoro-2-iodobenzene Property
- Boiling point:
- 247.4±25.0 °C(Predicted)
- Density
- 2.281
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- form
- liquid
- color
- Clear, colourless
- Sensitive
- Light Sensitive
- InChI
- InChI=1S/C6H3BrFI/c7-4-1-2-5(8)6(9)3-4/h1-3H
- InChIKey
- JNETZJWWXCLUKM-UHFFFAOYSA-N
- SMILES
- C1(F)=CC=C(Br)C=C1I
More
Less
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2903998090
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- B692333
- Product name
- 4-Bromo-1-fluoro-2-iodobenzene
- Packaging
- 500mg
- Price
- $45
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 020562
- Product name
- 4-Bromo-1-fluoro-2-iodobenzene
- Purity
- 98%
- Packaging
- 5g
- Price
- $10
- Updated
- 2021/12/16
AK Scientific
- Product number
- X8116
- Product name
- 4-Bromo-1-fluro-2-iodobenzene
- Packaging
- 5g
- Price
- $13
- Updated
- 2021/12/16
Apolloscientific
- Product number
- PC2532
- Product name
- 5-Bromo-2-fluoroiodobenzene
- Purity
- 99%
- Packaging
- 25g
- Price
- $18
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 020562
- Product name
- 4-Bromo-1-fluoro-2-iodobenzene
- Purity
- 98%
- Packaging
- 25g
- Price
- $19
- Updated
- 2021/12/16
More
Less
4-Bromo-1-fluoro-2-iodobenzene Chemical Properties,Usage,Production
Chemical Properties
Yellow crstalline
Uses
4-Bromo-1-fluoro-2-iodobenzene is a polyhalogenated benzene derivative containing substitutable reactive groups of fluorine, bromine and iodine atoms in its molecular structure. It is mainly used as a molecular building block, organic synthesis or pharmaceutical intermediate compound, and is a raw material for the preparation of other aromatic alkanes or heterocyclic compounds.
Synthesis
2924-09-6
116272-41-4
Under argon protection, 5-bromo-2-fluoroaniline (45.6 g, 240 mmol) was dissolved in water (120 mL), stirred and concentrated hydrochloric acid (120 mL) was added slowly. After the reaction mixture was cooled to -20 °C, aqueous sodium nitrite (19.9 g, 288 mmol dissolved in 80 mL of water) was added dropwise. Stirring was continued at -20 °C for 20 min, followed by the addition of aqueous potassium iodide solution (59.8 g, 360 mmol dissolved in 60 mL of water) and stirring was continued for 30 min. After completion of the reaction, the reaction mixture was extracted with hexane and the organic layer was washed sequentially with saturated aqueous sodium bicarbonate and sodium sulfite solutions and dried over anhydrous sodium sulfate. After evaporation of the solvent under reduced pressure, the residue was purified by silica gel column chromatography to afford 5-bromo-2-fluoroiodobenzene (54.6 g, 181 mmol) in 76% yield.
References
[1] Patent: KR2016/18458, 2016, A. Location in patent: Paragraph 0309-0311
[2] Patent: EP2924029, 2015, A1. Location in patent: Paragraph 0130; 0131
4-Bromo-1-fluoro-2-iodobenzene Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
4-Bromo-1-fluoro-2-iodobenzene Suppliers
- Tel
- 022-58013646 13011382049
- Fax
- 022-23854368
- sales@jinyudachem.com
- Country
- China
- ProdList
- 1930
- Advantage
- 55
- Tel
- 022-60189726 18812034280
- Fax
- 86-22-60979672
- 188120342808@163.com
- Country
- China
- ProdList
- 142
- Advantage
- 61
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 94644
- Advantage
- 76
- Tel
- 0418-6530555 2855550
- Fax
- +86-418-6502885
- Country
- China
- ProdList
- 338
- Advantage
- 69
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- +86-21-54098501
- Fax
- +86-21-54096319
- sales@sinch.com.cn
- Country
- China
- ProdList
- 11598
- Advantage
- 64
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9309
- Advantage
- 66
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9883
- Advantage
- 59
- Tel
- 021-31038972,31038973 17321035817
- Fax
- +86-21-51385350
- sales@harvest-chem.com
- Country
- China
- ProdList
- 2816
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 0571-82693216
- Fax
- +86-571-82880190
- info@yuhaochemical.com
- Country
- China
- ProdList
- 6387
- Advantage
- 52
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 0512-65617459 18915409046
- Fax
- 0512-65617459
- sales@sibian-chem.com
- Country
- China
- ProdList
- 1922
- Advantage
- 55
- Tel
- +86-21-60341587
- Fax
- +86-21-61294319
- sales@topbiochem.com
- Country
- China
- ProdList
- 6175
- Advantage
- 58
- Tel
- 025-66113011 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19913
- Advantage
- 55
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- 0371-86615086 18203638366 0371-86159066 13526786601
- Fax
- 0371-86159066
- Country
- China
- ProdList
- 2015
- Advantage
- 60
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 021-62960152
- Fax
- 021-52212593
- 934678158@qq.com
- Country
- China
- ProdList
- 9899
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 86-21-51086038
- Fax
- 86-21-51861608
- Country
- China
- ProdList
- 2930
- Advantage
- 58
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9476
- Advantage
- 58
- Tel
- sales@ahpharmatech.com
- Country
- China
- ProdList
- 5734
- Advantage
- 55
- Tel
- 021-69106960 13701823733
- Fax
- 021-69106780
- 13701823733@163.com
- Country
- China
- ProdList
- 4641
- Advantage
- 60
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 010-1234567 18521000990
- Fax
- 86-021-33275113
- sonyuanchemical@163.com
- Country
- China
- ProdList
- 6479
- Advantage
- 50
- Tel
- 010-56218822 13717722232
- Fax
- 010-56218800
- xinsavichem@163.com
- Country
- China
- ProdList
- 3201
- Advantage
- 56
- Tel
- 13718199399
- Fax
- QQ : 206661479
- holiyangchem@163.com
- Country
- China
- ProdList
- 3280
- Advantage
- 56
- Tel
- 021-69005955 13701776567
- Fax
- 021-69005775
- youpengchem@163.com
- Country
- China
- ProdList
- 4161
- Advantage
- 56
- Tel
- 13708085536 13708085536
- Fax
- QQ : 121102042
- hanovichem@163.com
- Country
- China
- ProdList
- 3282
- Advantage
- 56
- Tel
- 021-021-69182866 13701855675
- Fax
- 021-69182022
- tongyuanchem@126.com
- Country
- China
- ProdList
- 4193
- Advantage
- 58
- Tel
- 021-33516722 13701817765
- Fax
- 021-33516776
- kaisaichem@163.com
- Country
- China
- ProdList
- 4610
- Advantage
- 58
- Tel
- 13716033033
- Fax
- 010-56276266
- hanchochem@163.com
- Country
- China
- ProdList
- 2960
- Advantage
- 50
- Tel
- 021-69515658 ; 69515628 13701998368
- Fax
- 021-69515998
- longrunchem@163.com
- Country
- China
- ProdList
- 3786
- Advantage
- 50
- Tel
- 021-69992220 13701886816
- Fax
- 021-69992237
- roleadchem@163.com
- Country
- China
- ProdList
- 4613
- Advantage
- 50
- Tel
- 021-69185552 13701777608
- Fax
- 021-69186006
- kangtuochem@163.com
- Country
- China
- ProdList
- 4232
- Advantage
- 55
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 86(21)68097365
- Fax
- 86(21)33321566
- sales@anpharma.net
- Country
- China
- ProdList
- 4891
- Advantage
- 55
- Tel
- 13912302692 13912302692;
- Fax
- 0519-88064678
- sales@anxuanchem.com
- Country
- China
- ProdList
- 4828
- Advantage
- 58
- Tel
- 025-58862853 18915922038
- Fax
- +86-025-58862853
- sales@endesachem.com
- Country
- China
- ProdList
- 591
- Advantage
- 58
- Tel
- 0371-0371-67759225 13526468238
- Fax
- 0371-55919558
- sales@hqmat.com
- Country
- China
- ProdList
- 342
- Advantage
- 55
- Tel
- 0371-53765687 18937137882
- Fax
- QQ:2885373884
- 2853979813@qq.com
- Country
- China
- ProdList
- 7991
- Advantage
- 55
- Tel
- 15902145085
- Fax
- -
- 657990292@qq.com
- Country
- China
- ProdList
- 668
- Advantage
- 50
- Tel
- 028-85005297 13980656781
- Fax
- 028-85005529
- jingxin73730@163.com
- Country
- China
- ProdList
- 3280
- Advantage
- 50
More
Less
View Lastest Price from 4-Bromo-1-fluoro-2-iodobenzene manufacturers
Zhengzhou Anbu Chem Co.,Ltd
- Product
- 3-Iodo-4-fluorobromobenzene 116272-41-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1000KGS
- Release date
- 2023-07-03
Henan Fengda Chemical Co., Ltd
- Product
- 3-Iodo-4-fluorobromobenzene 116272-41-4
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-26
Career Henan Chemical Co
- Product
- 3-Iodo-4-fluorobromobenzene 116272-41-4
- Price
- US $2.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- ask
- Release date
- 2018-12-20
116272-41-4, 4-Bromo-1-fluoro-2-iodobenzeneRelated Search:
1,3-Dibromobenzene
Chlorfenapyr
3-Bromo-4-methylpyridine
3-Bromo-4-fluorobenzaldehyde
4-Bromofluorobenzene
3-Fluoro-4-broMoaniline
1-BROMO-2-FLUORO-4-IODOBENZENE
3-Fluoro-4-iodoaniline
1-BROMO-3-FLUORO-4-IODOBENZENE
1,2-Dibromobenzene
5-CHLORO-2-FLUOROIODOBENZENE
4-Bromo-2-fluoroaniline
2-Fluoro-4-iodoaniline
2-Bromo-4-chloro-1-iodobenzene
4-BROMO-2,6-DIFLUOROBENZYL BROMIDE
2-Chloro-1-(3,4-difluoro-phenyl)-ethanone
N-Fluorobenzenesulfonimide
2-Iodo-4-fluorobromobenzene