Basic information Safety Supplier Related

ganoderenic acid A

Basic information Safety Supplier Related

ganoderenic acid A Basic information

Product Name:
ganoderenic acid A
Synonyms:
  • ganoderenic acid A
  • (20E)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanosta-8,20(22)-dien-26-oic acid
  • (20E)-7β,15α-Dihydroxy-3,11,23-trioxolanosta-8,20(22)-diene-26-oic acid
  • Lanosta-8,20(22)-dien-26-oicacid, 7,15-dihydroxy-3,11,23-trioxo-, (7b,15a,20E)-
  • Lanosta-8,20(22)-dien-26-oic acid, 7,15-dihydroxy-3,11,23-trioxo-, (7β,15α,20E)-
  • 5R)-2-Isopropyl-5-Methylcyclohexanol
  • (E)-6-((5R,7S,10S,13R,14R,15S,17R)-7,15-Dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxohept-5-enoic acid
CAS:
100665-40-5
MF:
C30H42O7
MW:
514.66
Mol File:
100665-40-5.mol
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ganoderenic acid A Chemical Properties

Boiling point:
700.3±60.0 °C(Predicted)
Density 
1.24±0.1 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
4.65±0.23(Predicted)
color 
White to off-white
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ganoderenic acid A Usage And Synthesis

Description

Ganoderenic acid A is a triterpenoid originally isolated from G. lucidum that has enzyme inhibitory activities. It is an inhibitor of β-glucuronidase (IC50 = 0.12 mg/ml in rat liver microsomes). Ganoderenic acid A (100 mg/kg) reduces increases in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in a rat model of liver injury induced by carbon tetrachloride (CCl4). It also inhibits aldose reductase by 54.2% when used at a concentration of 100 μg/ml.

Definition

ChEBI: Ganoderenic acid A is a triterpenoid.

ganoderenic acid ASupplier

Shanghai YuanYe Biotechnology Co., Ltd. Gold
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