demethylzeylasteral
demethylzeylasteral Basic information
- Product Name:
- demethylzeylasteral
- Synonyms:
-
- demethylzeylasteral
- (9beta,13alpha,14beta,20alpha)-2,3-Dihydroxy-9,13-dimethyl-6,23-dioxo-24,25,26-trinoroleana-1,3,5(10),7-tetraen-29-oic acid
- A-Friedo-24-noroleana-1,3,5(10),7-tetraen-29-oicacid
- Demethylzeylasteral(T-96)
- 24,25,26-Trinoroleana-1,3,5(10),7-tetraen-29-oic acid, 2,3-dihydroxy-9,13-dimethyl-6,23-dioxo-, (9β,13α,14β,20α)-
- (2R,4AS,6aS,12bR,14aS,14bR)-9-formyl-10,11-dihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid
- CAS:
- 107316-88-1
- MF:
- C29H36O6
- MW:
- 480.59
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 107316-88-1.mol
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demethylzeylasteral Chemical Properties
- Melting point:
- >221°C (dec.)
- Boiling point:
- 663.6±55.0 °C(Predicted)
- Density
- 1.31
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.78±0.70(Predicted)
- color
- Yellow
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demethylzeylasteral Usage And Synthesis
Uses
Demethylzeylasteral is a natural product as new inhibitor to block the Bcl-XL-Bid interaction. Also, it is an immunosuppressive monomer isolated from the root xylem of Tripterygium wilfordii. It exhibits inhibition towards the glucuronidation elimination reaction of SN-38.
Definition
ChEBI: A carbopolycyclic compound with formula C29H36O6, originally isolated from Tripterygium wilfordii.
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