3-Azetidinecarboxylic acid Chemical Properties

Melting point:

286 °C (dec.) (lit.)

Boiling point:

189.47°C (rough estimate)

Density 

1.2245 (rough estimate)

refractive index 

1.4540 (estimate)

storage temp. 

Sealed in dry,2-8°C

solubility 

Water (Slightly)

form 

Solid

pka

2.74±0.20(Predicted)

color 

White to Off-White

Water Solubility 

Soluble in water.

InChIKey

GFZWHAAOIVMHOI-UHFFFAOYSA-N

CAS DataBase Reference

36476-78-5(CAS DataBase Reference)

EPA Substance Registry System

3-Azetidinecarboxylic acid (36476-78-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

24/25-22-36-26

WGK Germany 

3

RTECS 

CM4310600

HazardClass 

IRRITANT

HS Code 

29349990

Toxicity

LD50 orl-rat: >5 g/kg FMCHA2 -,C65,91

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

3-Azetidinecarboxylic acid Usage And Synthesis

Chemical Properties

light yellow powder

Uses

Azetidine-3-carboxylic acid derivatives has potential biological and foldameric applications. Azetidine-3-carboxylic acid, a fairly strained molecule provides oxadiazoles in good yields. Azetidine-3-carboxylic acid is used as a chemical hybridising agent

Uses

Azetidine and its derivatives are valuable compounds in pharmaceutical and agrochemical research.

Uses

3-Azetidinecarboxylic acid is a useful intermediate in the synthesis of polypeptides.

Safety Profile

Low toxicity by ingestion and skincontact. When heated to decomposition it emits toxicvapors of NOx.

3-Azetidinecarboxylic acid(36476-78-5)Related Product Information

• METHYL 1-(DIPHENYLMETHYL)AZETIDINE-3-CARBOXYLATE
• Fmoc-L-Azetidine-3-carboxylic acid
• 3-AZETIDINECARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
• 1-N-BOC-3-AZETIDINECARBOXYLIC ACID
• Methyl 1-Boc-azetidine-3-carboxylate
• 1-BENZYL-3-AZETIDINECARBOXYLIC ACID
• 1-BENZHYDRYL-3-AZETIDINECARBOXYLIC ACID
• (3R,4S)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylic acid 1,1-dimethylethyl ester
• (S)-(-)-2-Azetidinecarboxylic acid
• 3-(1-Ethoxyethoxy)-2-oxo-4-phenyl-1-azetidinecarboxylic acid 1,1-dimethylethyl ester
• 1-(4-CHLORO-BENZYL)-AZETIDINE-3-CARBOXYLIC ACID
• 1-BENZOYL-AZETIDINE-3-CARBOXYLIC ACID
• 3-(3-CARBOXY-AZETIDIN-1-YL)-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• 3-Azetidinecarboxylic acid
• AZETIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
• 1-TERT-BUTYL-2-AZETIDINECARBOXYLIC ACID
• 1-AZETIDINECARBOXYLIC ACID, 2-[[[2-NITRO-3-PYRIDINYL]OXY]METHYL]-, 1,1-DIMETHYLETHYL ESTER, (2S)-
• (2S)-2-[[[5-(TRIMETHYLSTANNYL)-3-PYRIDINYL]OXY]METHYL]-1-AZETIDINECARBOXYLIC ACID, T-BUTYL ESTER