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2-Ethylhexyl 4-hydroxybenzoate

Basic information Safety Supplier Related

2-Ethylhexyl 4-hydroxybenzoate Basic information

Product Name:
2-Ethylhexyl 4-hydroxybenzoate
Synonyms:
  • OCTYLPARABEN
  • P-HYDROXYBENZOIC ACID, 2-ETHYLHEXYL ESTER
  • 4-HYDROXYBENZOIC ACID OCTYL ESTER
  • 4'-HYDROXYBENZOIC ACID 2-ETHYLHEXYL ESTER
  • 4-HYDROXYBENZOIC ACID 2-ETHYLHEXYL ESTER
  • 2-ETHYLHEXYL 4-HYDROXYBENZOATE
  • 2-ETHYLHEXYLPARABEN
  • 2-ETHYLHEXYL P-HYDROXYBENZOATE
CAS:
5153-25-3
MF:
C15H22O3
MW:
250.33
EINECS:
225-925-9
Product Categories:
  • Aromatic Esters
Mol File:
5153-25-3.mol
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2-Ethylhexyl 4-hydroxybenzoate Chemical Properties

Boiling point:
270°C/50mmHg(lit.)
Density 
1.035±0.06 g/cm3(Predicted)
refractive index 
1.5190 to 1.5220
form 
clear liquid
pka
8.20±0.15(Predicted)
color 
Colorless to Light yellow to Light orange
LogP
5.292 (est)
CAS DataBase Reference
5153-25-3(CAS DataBase Reference)
EPA Substance Registry System
Benzoic acid, 4-hydroxy-, 2-ethylhexyl ester (5153-25-3)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37/39
HS Code 
2918290090
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2-Ethylhexyl 4-hydroxybenzoate Usage And Synthesis

Characteristics

The characteristics of 2-Ethylhexyl 4-hydroxybenzoate are: with the increase of the alkyl group in the paraben, the water solubility gradually decreases, the fat solubility increases gradually, the toxicity also decreases, and the antibacterial activity increases , in which esters of alkyl carbon chains with 11 and 12 carbons have the greatest antibacterial activity.

Uses

2-Ethylhexyl 4-hydroxybenzoate is a broad-spectrum, high-efficiency, low-toxicity food preservative, and one of the three major food preservatives recognized internationally.

Definition

ChEBI: 2-Ethylhexyl-4-hydroxybenzoate is a benzoate ester.

Synthesis

Synthesis of 2-Ethylhexyl 4-hydroxybenzoate usually uses p-hydroxybenzoic acid (P-hydroxybenzoic acid) and the corresponding alcohol for esterification to azeotrope with water agents (such as petroleum ether, benzene, toluene, cyclohexane, etc.)

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