4-BROMO-TETRAHYDROPYRAN Chemical Properties

Boiling point:

178℃

Density 

1.467 g/cm3 at 25 °C

refractive index 

n20/D1.497

Flash point:

69℃

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

clear liquid

color 

Colorless to Yellow to Orange

InChIKey

IVBVKTPDEWDNRW-UHFFFAOYSA-N

CAS DataBase Reference

25637-16-5

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

WGK Germany 

2

HS Code 

29321900

4-BROMO-TETRAHYDROPYRAN Usage And Synthesis

Chemical Properties

Light yellow liquid

Uses

Reactant for:

• Nickel-catalyzed alkyl-alkyl Suzuki coupling reactions with boron reagents
• Preparation of a selective small-molecule melanocortin-4 receptor agonist with efficacy in a pilot study of sexual dysfunction in humans
• Preparation of aliphatic hydrocarbons via nickel-catalyzed Suzuki cross-coupling with alkylboranes
• Preparation of anthranilic acids as antibacterial agents with human serum albumin binding affinity
• Preparation of antiatherogenic antioxidant di-tert-butyldihydrobenzofuranols via Grignard reactions with di-tert-butyl(hydroxy)benzaldehyde derivatives
• Synthesis of gephyrotoxin via the Schmidt reaction

Uses

4-Bromo-tetrahydropyran is a useful reactant in organic synthesis.

4-BROMO-TETRAHYDROPYRAN(25637-16-5)Related Product Information

• TETRAHYDRO-2H-PYRAN-3-OL
• 4-IODOTETRAHYDRO-2H-PYRAN
• (TETRAHYDRO-2H-PYRAN-4-YL)METHANOL
• 3,4-Dihydro-2H-pyran
• TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE
• Tetrahydro-2H-pyran-4-carboxylic acid
• 4-Aminotetrahydropyran
• Tetrahydro-4H-pyran-4-one
• 3,6-dihydro-2H-pyran
• Methyl tetrahydropyran-4-carboxylate
• 2-methyloxan-4-one
• Tetrahydro-4-pyranol
• 4-BROMOMETHYLTETRAHYDROPYRAN
• Tetrahydropyran
• 4-BROMO-TETRAHYDROPYRAN