1-Methyl-1H-indole-3-carboxylic acid Chemical Properties

Melting point:

197-200 °C (dec.) (lit.)

Boiling point:

389.0±15.0 °C(Predicted)

Density 

1.24±0.1 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

pka

4.01±0.10(Predicted)

form 

Crystalline Powder

color 

White to beige

CAS DataBase Reference

32387-21-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29339900

1-Methyl-1H-indole-3-carboxylic acid Usage And Synthesis

Chemical Properties

Off-white solid

Uses

• Reactant for preparation of bisindolyl pyrimidinones analogs of PKC inhibitor LY333531
• Reactant for preparation of (heteroaryl)(carboxamido)arylpyrrole derivatives as Cdc7 kinase inhibitors, antitumor and antiproliferative agents
• Reactant for preparation of (pyrrolidinylmethoxy)cyclohexanecarboxylic acids as antigen-4 (VLA-4) antagonists
• Reactant for preparation of EphB3 receptor tyrosine kinase inhibitors
• Reactant for preparation of pyrazolodiazepine derivatives as human P2X7 receptor antagonists
• Reactant for preparation of potent nonpeptidic urotensin II receptor agonists
• Reactant for preparation of pyrrolizidine esters, amides, and ureas as 5-HT4 receptor ligands

General Description

1-Methylindole-3-carboxylic acid is an indole derivative that can be prepared by the oxidation of 1-methylindole-3-aldehyde with alkaline potassium permanganate.

1-Methyl-1H-indole-3-carboxylic acid(32387-21-6)Related Product Information

• 3-(1-methyl-1H-indole-3-carbonyl)hexanedioic acid
• (3R)-2,3-Dihydro-3-(2-propyn-1-ylaMino)-1H-inden-1-one
• 1-Methylindole
• Ramosetron hydrochloride
• Rasagiline Impurity 5 Mesylate
• 5-(1-methyl-1H-indole-3-carbonyl)-1H-benzo[d]imidazol-2(3H)-one
• ramosetron
• 4,5,6,7-Tetrahydro-1H-benzoiMidazole-5-carboxylic acid hydrochloride
• Rasagiline Impurity 3
• 3a,7a-dihydroxy-5-(1-methyl-1H-indole-3-carbonyl)-hexahydro-1H-benzo[d]imidazol-2(3H)-one
• Ramosetron Impurity 13
• N-[4,5,6,7-Tetrahydrobenzimidazole-5-yl)carbonyl] pyrrolidine sulfate
• N-METHYLISATIN
• 1,2-DIMETHYLINDOLE-3-CARBOXYLIC ACID
• 5-Methylindole
• ETHYL5-ACETOXY-6-BROMO-2-(BROMOMETHYL)-1-METHYLINDOLE-3-.
• 5-METHYLINDOLE-3-CARBOXYLIC ACID METHYL ESTER
• ETHYL 5-METHYLINDOLE-2-CARBOXYLATE