4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT Chemical Properties

Melting point:

287-290°C

storage temp. 

-20°C

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

form 

Powder

color 

White to Pale Yellow

Water Solubility 

Soluble in water at 5mg/ml

BRN 

3803203

Stability:

Stable in unbuffered solution for several months at -20°

CAS DataBase Reference

15220-11-8(CAS DataBase Reference)

EPA Substance Registry System

2H-1-Benzopyran-2-one, 4-methyl-7-(sulfooxy)-, potassium salt (15220-11-8)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

8-10-21

TSCA 

Yes

HS Code 

29322090

MSDS

• Language:English Provider:SigmaAldrich

4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

4-Methylumbelliferyl sulfate potassium salt is a fluorometric substrate for the determination of sulfatase. This substrate has been used in the discovery of tyrosine sulfotransferase inhibitors, particularly in P-selectin glycoprotein ligand-1 binding. This compound is virtually non-fluorescent until cleavage by sulfatase enzymes, then emits blue fluorescence (450 nm) with excitation at 360 nm. Use of this compound in high-throughput fluorescence based screening led to the discovery of several potent beta-arylsulfotransferase IV (beta-AST-IV) inhibitors.

Uses

Met-enkephalin analog found in opioid extracts of brain and adrenal chromaffin cells that is an artifact generated by trichloroacetic acid extraction. MUS is used as a fluorimetric substrate for arylsulphatase enzyme. Subsitution of the hydroxyl group of 4-Methylumbelliferyl sulfate potassium salt causes the excitation wavelength of the umbelliferone to shift to shorter values and also brings about a decrease in fluorescence. Fluorescence: max. Abs = 334 mm; max. Em. = 370 mm

4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT(15220-11-8)Related Product Information

• 4-Methylumbelliferyl-beta-D-glucopyranoside
• 4-METHYLUMBELLIFERYL-BETA-D-LACTOSIDE
• (4-Methylumbelliferyl)-N-acetyl-α-D-neuraminic acid sodium salt
• 4-Methylumbelliferyl α-L-idopranosiduronic acid 2-sulphate sodium salt
• 4-Methylumbelliferylbeta-D-ribofuranoside
• 4-METHYLUMBELLIFERYL-BETA-D-XYLOPYRANOSIDE
• 4-METHYLUMBELLIFERYL-BETA-D-CELLOBIOPYRANOSIDE
• 4-methyl-2-oxo-2H-1-benzopyran-7-yl alpha-L-ido-pyranosiduronic acid
• 4-Methylumbelliferyl b-D-glucosaminide
• 4-METHYLUMBELLIFERYL-ALPHA-D-GLUCOPYRANOSIDE HYDRATE
• 4-Methylumbelliferyl 2-Sulfamino-2-deoxy-α-D-glucopyranoside Sodium Salt
• Potassium
• Potassium bisulfate
• Potassium methyl sulfate
• POTASSIUM HYDROGEN SULFITE
• 3-Hydroxyphenyl acetate
• 4-METHYLUMBELLIFERYL SULFATE POTASSIUM SALT
• 2-OXO-2H-1-BENZOPYRAN-7-YL-SULFATE POTASSIUM SALT