Basic information Safety Supplier Related

(+)-Ethyl D-lactate

Basic information Safety Supplier Related

(+)-Ethyl D-lactate Basic information

Product Name:
(+)-Ethyl D-lactate
Synonyms:
  • chiral grade ethyl lactate
  • ethyl (2R)-2-hydroxypropanoate
  • Natural D-Ethyl Lactate
  • (2R)-2-Hydroxy-Propanoic Acid Ethyl Ester
  • Propanoic acid, 2-hydroxy-, ethyl ester, (2R)- (9CI)
  • (+)-Ethyl (R)-2-hydroxypropionate, (R)-(+)-2-Hydroxypropionic acid ethyl ester
  • (2R)-2-Hydroxypropionic acid ethyl ester
  • (R)-2-Hydroxypropanoic acid ethyl
CAS:
7699-00-5
MF:
C5H10O3
MW:
118.13
Product Categories:
  • ACETYLGROUP
  • Pyrazoles
  • Miscellaneous Reagents
  • bc0001
Mol File:
7699-00-5.mol
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(+)-Ethyl D-lactate Chemical Properties

Boiling point:
150-153 °C
Density 
1.0345 g/cm3(Temp: 23 °C)
refractive index 
n20/D 1.413
Flash point:
46 °C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Sparingly), Methanol (Slightly)
form 
liquid
pka
13.21±0.20(Predicted)
color 
Colourless
BRN 
1720840
LogP
-0.188 (est)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
10-37-41
Safety Statements 
24-26-39
RIDADR 
UN 1192 3/PG 3
WGK Germany 
3
3
HazardClass 
3.2
PackingGroup 
III
HS Code 
2918199890
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(+)-Ethyl D-lactate Usage And Synthesis

Chemical Properties

(+)-Ethyl D-lactate has been shown to have a helical structure, which is different from the linear form of L-lactate. This difference has been modeled mathematically and confirmed by small-angle x-ray diffraction studies. (+)-Ethyl D-lactate has been shown to inhibit the virulence factor lipase in Pseudomonas aeruginosa, an important pathogen in cystic fibrosis patients. The drug can also be used as a vaporiser for the treatment of bacterial infections such as P. aeruginosa infections in cystic fibrosis patients, which can cause high blood pressure when left untreated.

Definition

ChEBI: (+)-Ethyl D-lactate is the ethyl ester obtained of 2-hydroxypropanoic acid. It has a role as a metabolite. (+)-Ethyl D-lactate is a secondary alcohol, a lactate ester and an ethyl ester. It is functionally related to a 2-hydroxypropanoic acid.

Synthesis

(+)-Ethyl D-lactate is a synthetic compound that is used for the synthesis of lactates and other esters. It can be synthesized from ethyl alcohol and lactic acid by titration calorimetry.

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