3,5-Dichlorophenol Chemical Properties

Melting point:

65-68 °C (lit.)

Boiling point:

233 °C (lit.)

Density 

1.3446 (rough estimate)

refractive index 

1.4430 (estimate)

Flash point:

233°C

storage temp. 

room temp

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Crystals, Crystalline Powder or Crystalline Mass

pka

pKa 8.48(H2O t=25 I=0.025) (Uncertain)

color 

Yellow to light brown

Water Solubility 

Slightly soluble in water. Very soluble in ethanol, ethyl ether and petroleum ether.

BRN 

1906458

CAS DataBase Reference

591-35-5(CAS DataBase Reference)

NIST Chemistry Reference

Phenol, 3,5-dichloro-(591-35-5)

EPA Substance Registry System

3,5-Dichlorophenol (591-35-5)

Safety Information

Hazard Codes 

Xn,Xi,T

Risk Statements 

22-36/38-36/37/38-23/24/25

Safety Statements 

26-28-37/39-45

RIDADR 

UN 2020 6.1/PG 3

WGK Germany 

3

RTECS 

SK8820000

Hazard Note 

Harmful

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29081990

Hazardous Substances Data

591-35-5(Hazardous Substances Data)

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3,5-Dichlorophenol Usage And Synthesis

Chemical Properties

yellow to light brown crystals, crystalline powder

Uses

3,5-Dichlorophenol is used as pharmaceutical intermediate.

Application

3,5-Dichlorophenol is a metabolite of the pesticides polychlorinated phenols and benzene hexachloride. found in chlorinated waste water; Used as a research chemical.

Preparation

Catalytic hydrodechlorination of polychlorophenols in organic or aqueous media with a palladium catalyst was used to obtain 3-chlorophenol and 3,5-dichlorophenol.

Definition

ChEBI: 3,5-dichlorophenol is a dichlorophenol in which the two chloro substituents are located at positions 3 and 5.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 4565, 1984 DOI: 10.1016/S0040-4039(01)81494-5

General Description

Prisms (from petroleum ether) or pink crystals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

3,5-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Flash point data for 3,5-Dichlorophenol are not available. 3,5-Dichlorophenol is probably combustible.

Purification Methods

Crystallise 3,5-dichlorophenol from pet ether/*benzene mixture and/or distil it. [Beilstein 6 IV 957.]

3,5-Dichlorophenol(591-35-5)Related Product Information

• 1,2-Dichloro-4-(chloromethyl)benzene
• 2-Phenylphenol
• Dichloroethane
• N,N-Dimethylacetamide
• Thionyl chloride
• Sodium dichloroisocyanurate
• Quinclorac
• 4-Nitrophenol
• 2,3,5,6-TETRACHLOROPHENOL
• 3,5-Dichloroanisole
• Pentachlorophenol
• 2,3,5,6-TETRACHLOROANISOLE
• 2,4-DICHLOROPHENOL pract,2,4-DICHLOROPHENOL 99+%
• 2,5-Dichlorophenol
• 2,3-DICHLOROPHENOL 99+%
• PENTACHLOROPHENOL DODECANOATE
• 2,4-DICHLORO-6-HYDROXYBENZALDEHYDE
• 2,6-DICHLOROPHENOL extrapure