Acetophenone oxime Chemical Properties

Melting point:

55-60 °C (lit.)

Boiling point:

118-120 °C/20 mmHg (lit.)

Density 

1.11 g/mL at 25 °C (lit.)

refractive index 

1.5302 (rough estimate)

Flash point:

118-120°C/20mm

storage temp. 

-20°C

pka

11.43±0.70(Predicted)

form 

powder to crystal

color 

White to Light yellow

Water Solubility 

slightly soluble

Sensitive 

Air & Moisture Sensitive

BRN 

1562059

InChIKey

JHNRZXQVBKRYKN-CLFYSBASSA-N

CAS DataBase Reference

613-91-2(CAS DataBase Reference)

NIST Chemistry Reference

Ethanone, 1-phenyl-, oxime(613-91-2)

EPA Substance Registry System

Ethanone, 1-phenyl-, oxime (613-91-2)

Safety Information

Hazard Codes 

T,Xi

Risk Statements 

25-41-36/37/38

Safety Statements 

26-39-37/39

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

AM9654000

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29280090

Toxicity

LD50 orl-mus: 2 g/kg MEXPAG 11,137,64

MSDS

• Language:English Provider:Acetophenone oxime
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Acetophenone oxime Usage And Synthesis

Description

Acetophenone oxime is a solid but slightly soluble substance. Acetophenone oxime is incompatible with strong oxidising agents, moisture, acids, and metal and alkali compounds. Acetophenone oxime on decomposition releases irritating and toxic fumes and gases. There is no published data about the hazardous polymerisation of acetophenone oxime.

Chemical Properties

Acetophenone oxime is a solid but slightly soluble substance. It is incompatible with strong oxidizing agents, moisture, acids, metal, and alkali compounds. On decomposition, acetophenone oxime releases irritating and toxic fumes and gases. There are no published data about the hazardous polymerization of acetophenone oxime.

Chemical Properties

WHITE TO CREAM CRYSTALLINE POWDER

Uses

1-Phenylethanone Oxime is a useful reagent for organic synthesis

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 5089, 1987 DOI: 10.1021/jo00232a005
Tetrahedron Letters, 30, p. 5763, 1989 DOI: 10.1016/S0040-4039(00)76191-0

Health Hazard

Exposures to acetophenone oxime cause irritation to the eyes, skin, and the respiratory and digestive tracts. The toxicological properties of acetophenone oxime are not been fully investigated.

Safety Profile

Poison by an unspecified route.Slightly toxic by ingestion. When heated to decomposition itemits toxic vapors of NOx.

storage

Acetophenone oxime should be kept stored in a cool, dry place and in a closed container when not in use.

Precautions

On exposures to acetophenone oxime, occupational workers should immediately fl ush the eyes with plenty of water. Workers should use proper personal protective equipment, wear appropriate gloves to prevent skin exposure, and wear appropriate protective eyeglasses or chemical safety goggles as described.

Acetophenone oxime(613-91-2)Related Product Information

• 2'-Hydroxyacetophenone
• 2-Bromoacetophenone
• 3-Aminoacetophenone
• Dichloroacetonitrile
• 3-Nitroacetophenone
• 4'-Bromoacetophenone
• 4'-Hydroxyacetophenone
• 2',4'-Dichloroacetophenone
• Acetophenone
• 4-Nitroacetophenone
• 3-PHENYL-5-ISOXAZOLONE
• 2-HYDROXYIMINO-2-PHENYLACETONITRILE
• 9-FLUORENONE OXIME
• 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
• 2-AMINO-5-CHLOROBENZOPHENONE OXIME
• Benzophenone oxime
• 3-(TRIFLUOROMETHYL)ACETOPHENONE OXIME,3'-(TRIFLUOROMETHYL)ACETOPHENONE OXIME
• (+),(-)-A-2,4,5,7-TETRANITRO-9-FLUORENYLIDENEAMINOOXYPROPIONIC ACID