Basic information Safety Supplier Related

3-isomangostin

Basic information Safety Supplier Related

3-isomangostin Basic information

Product Name:
3-isomangostin
Synonyms:
  • 3-isomangostin
  • 3,4-Dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-2H,6H-pyrano[3,2-b]xanthen-6-one
  • 3,4-dihydro-5,9-dihydroxy-8-Methoxy-2,2-diMethyl-7-(3-Methylbut-2-enyl)pyrano[3,2-b]xanthen-6(2H)-one
  • 3-Isomangostin, 98%, from Garcinia mangostana L.
  • 5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one
  • 2H,6H-Pyrano[3,2-b]xanthen-6-one, 3,4-dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-
  • ISOMANGOSTIN, 3-
CAS:
19275-46-8
MF:
C24H26O6
MW:
410.46
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
19275-46-8.mol
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3-isomangostin Chemical Properties

Melting point:
155~160℃
Boiling point:
615.9±55.0 °C(Predicted)
Density 
1.257
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
pka
7.04±0.40(Predicted)
color 
Yellow
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3-isomangostin Usage And Synthesis

Uses

3-Isomangostin has been discovered as being a new class of MTH1 inhibitor using X-ray crystallography screening, as well as, an inhibitor of amyloidogenesis, which can reduce amyloid fibril formation by human V30M transthyretin variant. It has also been used to prepare novel xanthone derivative to use against cancer.

Definition

ChEBI: 3-Isomangostin is a member of xanthones.

3-isomangostinSupplier

Chembest Research Laboratories Limited
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Chengdu Biopurify Phytochemicals Ltd.
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Chengdu Climax Biotech Co., Ltd.
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Beijing HuaMeiHuLiBiological Chemical
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