Tetramethylthiourea Chemical Properties

Melting point:

75-77 °C (lit.)

Boiling point:

245 °C (lit.)

Density 

1.005 (estimate)

refractive index 

1.5300 (estimate)

Flash point:

190 °C

storage temp. 

2-8°C

solubility 

32g/l

form 

solid

pka

1.50±0.50(Predicted)

color 

Off-White to Pale Beige

Water Solubility 

32 g/L (20 ºC)

BRN 

1744916

InChIKey

MNOILHPDHOHILI-UHFFFAOYSA-N

CAS DataBase Reference

2782-91-4(CAS DataBase Reference)

NIST Chemistry Reference

Thiourea, tetramethyl-(2782-91-4)

EPA Substance Registry System

Tetramethylthiourea (2782-91-4)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-20/21/22

Safety Statements 

22-24/25-36

WGK Germany 

3

RTECS 

YU2750000

TSCA 

Yes

HS Code 

29309070

Hazardous Substances Data

2782-91-4(Hazardous Substances Data)

MSDS

• Language:English Provider:1,1,3,3-Tetramethyl-2-thiourea
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Tetramethylthiourea Usage And Synthesis

Chemical Properties

COLORLESS TO YELLOW CRYSTALLINE CHUNKS

Uses

As a drug.

Uses

Tetramethylthiourea forms BF3 adduct with tetramethylselenourea.

Definition

ChEBI: Tetramethylthiourea is a member of thioureas.

General Description

White crystals.

Air & Water Reactions

Water soluble.

Reactivity Profile

An organosulfide amide. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Hazard

Moderately toxic by ingestion.

Fire Hazard

Flash point data for Tetramethylthiourea are not available, but Tetramethylthiourea is probably combustible.

Safety Profile

Moderately toxic by ingestion. Questionable carcinogen with experimental carcinogenic and teratogenic data. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also SULFIDES.

Tetramethylthiourea(2782-91-4)Related Product Information

• N-Aminothiourea
• Methylthiouracil
• 1-PHENYL-2-THIOUREA
• N,N'-DIMETHYLTHIOUREA
• N,N'-Diethylthiourea
• N-METHYLTHIOUREA
• Thiourea dioxide
• Ethylene thiourea
• Allylthiourea
• Tetramethylsilane
• Tetramethylpyrazine
• 2-(4-Methoxyphenyl)-3,5,7-trimethoxy-4H-1-benzopyran-4-one
• Tetramethylthiuram Disulfide
• Carbimazole
• 1,3-DIETHYL-2-THIOBARBITURIC ACID
• AKOS B029106
• PHENYLTHIOHYDANTOIN-PROLINE
• MTH-DL-PROLINE