Basic information Safety Supplier Related

1,2,3,4,8,9,10,11-OCTAHYDRO[1,4]DIAZEPINO[6,7,1-JK]CARBAZOLE HYDROCHLORIDE

Basic information Safety Supplier Related

1,2,3,4,8,9,10,11-OCTAHYDRO[1,4]DIAZEPINO[6,7,1-JK]CARBAZOLE HYDROCHLORIDE Basic information

Product Name:
1,2,3,4,8,9,10,11-OCTAHYDRO[1,4]DIAZEPINO[6,7,1-JK]CARBAZOLE HYDROCHLORIDE
Synonyms:
  • WAY 629 HYDROCHLORIDE
  • 1,2,3,4,8,9,10,11-OCTAHYDRO[1,4]DIAZEPINO[6,7,1-JK]CARBAZOLE HYDROCHLORIDE
  • 4,5,6,7,9,10,11,12-Octahydro[1,4]diazepino[6,7,1-jk]carbazole
  • [1,4]Diazepino[6,7,1-jk]carbazole, 4,5,6,7,9,10,11,12-octahydro-
  • WAY 629 hydrochlorid
CAS:
57756-45-3
MF:
C15H18N2
MW:
226.32
Product Categories:
  • Serotonin receptor
Mol File:
57756-45-3.mol
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1,2,3,4,8,9,10,11-OCTAHYDRO[1,4]DIAZEPINO[6,7,1-JK]CARBAZOLE HYDROCHLORIDE Chemical Properties

Melting point:
114-115℃
storage temp. 
Desiccate at +4°C
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1,2,3,4,8,9,10,11-OCTAHYDRO[1,4]DIAZEPINO[6,7,1-JK]CARBAZOLE HYDROCHLORIDE Usage And Synthesis

Uses

WAY 629 is a selective SR-2C agonist. Potent and efficacious 5-HT2C receptor agonists.

Definition

ChEBI: LSM-3233 is a member of carbazoles.

Biological Activity

Selective 5-HT 2C agonist. K i values are 56, 2350, 1575 and 815 nM for human recombinant 5-HT 2C , 5-HT 2A , 5-HT 6 and 5-HT 7 receptors respectively. Stimulates intracellular Ca 2+ mobilization in CHO cells expressing human 5-HT 2C receptors (EC 50 = 72 nM). Reduces food intake in rats.

1,2,3,4,8,9,10,11-OCTAHYDRO[1,4]DIAZEPINO[6,7,1-JK]CARBAZOLE HYDROCHLORIDESupplier

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