3,5-Difluoroanisole Chemical Properties

Boiling point:

145-148°C

Density 

1.234 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.466(lit.)

Flash point:

111 °F

storage temp. 

Sealed in dry,2-8°C

form 

Liquid

Specific Gravity

1.234

color 

Clear colorless

BRN 

4966844

CAS DataBase Reference

93343-10-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,F

Risk Statements 

10-36/37/38

Safety Statements 

16-26-36/37/39-7/9

RIDADR 

UN 1993 3/PG 3

WGK Germany 

3

Hazard Note 

Flammable

HazardClass 

3

PackingGroup 

III

HS Code 

29093090

MSDS

• Language:English Provider:3,5-Difluoroanisole
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3,5-Difluoroanisole Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

3,5-Difluoroanisole is used in the preparation of indazole arylsulfonamides as allosteric CC-chemokine receptor 4 antagonists. Also used in the preparation of imidazo[1,5-a]pyrido[3,2-e]pyrazines and imidazo[1,5-a]quinoxalines as orally active phosphodiesterase 10A inhibitors.

General Description

The structure and vibrations of 3,5-difluoroanisole in first electronically excited state were studied by mass-analyzed resonant two-photon ionization technique as well as the quantum chemical calculations.

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