FG-4592 interMediate Chemical Properties

Boiling point:

534.7±45.0 °C(Predicted)

Density 

1.320±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

pka

5.80±0.50(Predicted)

InChI

InChI=1S/C17H13NO4/c1-21-17(20)15-16(19)14-8-7-13(9-11(14)10-18-15)22-12-5-3-2-4-6-12/h2-10,19H,1H3

InChIKey

YTWDBRIDKWWANA-UHFFFAOYSA-N

SMILES

C1C2=C(C=CC(OC3=CC=CC=C3)=C2)C(O)=C(C(OC)=O)N=1

FG-4592 interMediate Usage And Synthesis

Uses

Methyl 4-Hydroxy-7-phenoxyisoquinoline-3-carboxylate is an intermediate of N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine (H948180), a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.

FG-4592 interMediate(1455091-10-7)Related Product Information

• 4-Hydroxybenzyl alcohol
• 6-BROMO-3 H-ISOBENZOFURAN-1-ONE
• methyl 7-bromo-4-hydroxyisoquinoline-3-carboxylate
• methyl 4-hydroxy-6-phenoxyisoquinoline-3-carboxylate
• (R)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-onehydrochloride
• 7,8-dihydro-5H-cyclohepta[b]pyridine-5,9(6H)-dione
• 2-(2-Methyl-2H-tetrazol-5-yl)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine
• 1-(1-(1H-imidazole-1-carbonyl)piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one
• 4-Aminophthalimide
• 5-Aminophthalide
• 1(3H)-Isobenzofuranone, 5-phenoxy-
• INDEX NAME NOT YET ASSIGNED
• methyl 2-(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxamido)acetate
• methyl 1-chloro-4-hydroxy-7-phenoxyisoquinoline-3-carboxylate
• Roxadustat
• 4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinecarboxylic acid methyl ester