5-Methoxysalicylic acid Chemical Properties

Melting point:

141-143 °C(lit.)

Boiling point:

217.07°C (rough estimate)

Density 

1.1816 (rough estimate)

refractive index 

1.4611 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

3.01±0.10(Predicted)

form 

Fine Crystalline Powder

color 

Beige

Water Solubility 

1.7 g/L (10 ºC)

BRN 

2209647

InChIKey

IZZIWIAOVZOBLF-UHFFFAOYSA-N

LogP

2.100 (est)

CAS DataBase Reference

2612-02-4(CAS DataBase Reference)

EPA Substance Registry System

Benzoic acid, 2-hydroxy-5-methoxy- (2612-02-4)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36

WGK Germany 

3

TSCA 

Yes

HS Code 

29189900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

5-Methoxysalicylic acid Usage And Synthesis

Description

5-Methoxysalicylic acid is a chemical compound belongs to the class of organic compounds known as m-methoxybenzoic acids and derivatives. It is a component of castoreum, the exudate from the castor sacs of the mature beaver.
A mixture of 5-methoxysalicylic acid and spermine can be used as a matrix for oligonucleotides analysis in MALDI mass spectrometry.
It is an isomer of vanillic acid.
2-Hydroxy-5-methoxybenzoic acid is matrix additive which enhances the electrical conductivity of the matrix crystal during matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).

Chemical Properties

beige fine crystalline powder

Uses

5-Methoxysalicylic acid was used to evaluate MALDI matrix/solvent combinations for intact spore mass spectrometry of Fusarium species.

Uses

2-Hydroxy-5-methoxybenzoic acid was used to evaluate MALDI matrix/solvent combinations for intact spore mass spectrometry of Fusarium species.

Definition

ChEBI:5-methoxysalicylic acid is a methoxysalicylic acid that is salicylic acid which is carrying a methoxy group at position 5. It has a role as a bacterial metabolite and a human urinary metabolite.

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 2301, 1950 DOI: 10.1021/ja01161a530

General Description

2-Hydroxy-5-methoxybenzoic acid is matrix additive which enhances the electrical conductivity of the matrix crystal during matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).

5-Methoxysalicylic acid(2612-02-4)Related Product Information

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• 5-Methylsalicylic acid
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• CHLOROPHOSPHONAZO III
• 4-METHOXYSALICYLIC ACID 99%,4-METHOXYSALICYLIC ACID
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• FUMARPROTOCETRARIC ACID