(R)-(+)-3-HYDROXY-3-METHYL-4,4,4-TRICHLOROBUTYRIC BETA-LACTONE Chemical Properties

Melting point:

43-44 °C (lit.)

Boiling point:

120 °C/0.1 mmHg (lit.)

Density 

1.6184 (rough estimate)

refractive index 

1.4505 (estimate)

Flash point:

>230 °F

storage temp. 

2-8°C

optical activity

[α]26/D +6.0°, c = 2 in ethanol

BRN 

5730854

InChI

1S/C5H5Cl3O2/c1-4(5(6,7)8)2-3(9)10-4/h2H2,1H3/t4-/m1/s1

InChIKey

MIYJBPXTAZJPGX-SCSAIBSYSA-N

SMILES

C[C@@]1(CC(=O)O1)C(Cl)(Cl)Cl

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38

Safety Statements 

26-36

WGK Germany 

3

F 

8-10-21

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

• Language:English Provider:SigmaAldrich

(R)-(+)-3-HYDROXY-3-METHYL-4,4,4-TRICHLOROBUTYRIC BETA-LACTONE Usage And Synthesis

Uses

(4R)-4-Methyl-4-(trichloromethyl)-2-oxetanone can be used as LPA1 receptor antagonists to treat fibrosis.

Uses

(R)-(+)-4-Methyl-4-(trichloromethyl)-2-oxetanone may be used in the preparation of (S)-citramalic acid.

(R)-(+)-3-HYDROXY-3-METHYL-4,4,4-TRICHLOROBUTYRIC BETA-LACTONE(93239-42-0)Related Product Information

• 4-CHLOROBUTYRIC ACID
• Chlorobutanol
• 1-CHLORO-2-METHYL-2-PROPANOL
• (R)-1-Chloro-2-propanol
• 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
• TRIMETHYLENE OXIDE
• 2-Oxetanone
• BETA-BUTYROLACTONE
• 2,2,2-TRICHLOROETHYL ACETATE
• 4-Chloro-1-butanol
• (S)-(+)-1-CHLORO-2-METHYLBUTANE
• 4,4,4-TRICHLOROBUTYRIC ACID
• (S)-1-Chloro-2-propanol
• 1,1,1-TRICHLORO-2-PROPANOL
• (S)-(-)-3-HYDROXY-3-METHYL-4,4,4-TRICHLOROBUTYRIC BETA-LACTONE
• (R)-(+)-3-HYDROXY-3-METHYL-4,4,4-TRICHLOROBUTYRIC BETA-LACTONE
• 1-CHLORO-2-METHYL-2-BUTANOL
• (R)-4-(TRICHLOROMETHYL)-2-OXETANONE