TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD
TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD Basic information
- Product Name:
- TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD
- Synonyms:
-
- DOTA-tris(t-Bu ester)
- Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate DOTA-tris(tBu)ester
- 2-[4,7,10-tris[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
- (4,7,10-Tris-tert-butoxycarbonylmethyl-1,4,7,10tetraaza-cyclododec-1-yl)-acetic acid
- Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate
- DOTA-tris(tert-butyl ester) Novabiochem
- 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1,4,7-tris(1,1-dimethylethyl) ester
- TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD
- CAS:
- 137076-54-1
- MF:
- C28H52N4O8
- MW:
- 572.73
- Product Categories:
-
- RDC Linker
- PDC Linker
- Mol File:
- 137076-54-1.mol
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TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD Chemical Properties
- Melting point:
- 129-131℃
- Boiling point:
- 632.1±55.0 °C(Predicted)
- Density
- 1.079
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Aqueous Base (Slightly), Chloroform (Slightly), DMSO (Slightly),Methanol(Slightly)
- form
- Solid
- pka
- 4.24±0.10(Predicted)
- color
- Pale Beige
- InChI
- InChI=1S/C28H52N4O8/c1-26(2,3)38-23(35)19-30-12-10-29(18-22(33)34)11-13-31(20-24(36)39-27(4,5)6)15-17-32(16-14-30)21-25(37)40-28(7,8)9/h10-21H2,1-9H3,(H,33,34)
- InChIKey
- RVUXZXMKYMSWOM-UHFFFAOYSA-N
- SMILES
- N1(CC(OC(C)(C)C)=O)CCN(CC(O)=O)CCN(CC(OC(C)(C)C)=O)CCN(CC(OC(C)(C)C)=O)CC1
- CAS DataBase Reference
- 137076-54-1
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TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD Usage And Synthesis
Description
DOTA(OtBu)3 contains a DOTA moiety with t-butyl groups which can be used as a chelating agent for cations and is commonly used for imaging diagnostics. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
DOTA-tris (t-Bu ester), is a Bifunctional chelator, that can be used in the preparation of gadolinium complexes as MRI blood contrast agents.
Uses
Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetate (tri BOC-DOTA) can be employed as a reactant to prepare:
- Gadolinium ion functionalized with DOTA-LAE (lactobionic acid-ethylenediamine), which is used as a contrast agent for magnetic resonance imaging (MRI).
- DOTA-conjugates of ursolic acid and ZD2 peptide 64Cu-DOTA conjugates.
TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD Preparation Products And Raw materials
Raw materials
TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODODSupplier
Dream Chemical (Tianjin) Co., Ltd Gold
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- 022-8371-7680 18522952724
- public@dreamchem.cn
Grice Rand (Tianjin) Pharmaceutical Co., Ltd. Gold
- Tel
- 022-83705301 13752403750
- 2966024760@qq.com
Quzhou AMK BioTech Co., Ltd Gold
- Tel
- 0570-3081766 18357083060
- sales@qzamkbio.com
Shangfluoro Gold
- Tel
- 021-021-65170832 13331983812
- qinba_2@163.com
Shouguang Xinghai Chemical Co. LTD Gold
- Tel
- 15666881566
- 449211804@qq.com
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TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD(137076-54-1)Related Product Information
- Tri-tert-butylphosphine
- TRI-TERT-BUTYLPHOSPHONIUM TETRAPHENYLBORATE
- Tri-tert-butylphosphine tetrafluoroborate
- Methyl trichloroacetate
- 1,4,7-tris-Boc-1,4,7,10-tetraaza-cyclododecane
- Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetate HydrobroMide
- TRI-T-BUTYL 1 4 7 10-TETRAAZACYCLODODECA
- 1,4,7-Tris(ethoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane
- DOTA
- TRI-TERT-BUTYL 1 4 7 10-TETRAAZACYCLODOD
- 1,7-Bis(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane
- Cyclen