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(R)-(+)-1-(4-Methoxyphenyl)ethylamine

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(R)-(+)-1-(4-Methoxyphenyl)ethylamine Basic information

Product Name:
(R)-(+)-1-(4-Methoxyphenyl)ethylamine
Synonyms:
  • (1R)-1-(4-methoxyphenyl)ethanamine
  • (R)-p-Methoxyphenylethylamine
  • (R)-1-(4-methoxyphenyl)ethan-1-amine
  • Benzenemethanamine, 4-methoxy-.alpha.-methyl-, (.alpha.R)-
  • (1R)-1-(4-Methoxyphenyl)ethylamine
  • (R)-(+)-4-Methoxy-alpha-MethylbenzylaMine ChiPros(R), produced by BASF, 99%
  • R - the Methoxy phenethylaMine
  • (R)-(+)-4-Methoxy-
CAS:
22038-86-4
MF:
C9H13NO
MW:
151.21
EINECS:
606-907-3
Product Categories:
  • API intermediates
  • Amines (Chiral)
  • Chiral Building Blocks
  • Synthetic Organic Chemistry
  • Amines and Derivatives
  • CHIRAL CHEMICALS
Mol File:
22038-86-4.mol
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(R)-(+)-1-(4-Methoxyphenyl)ethylamine Chemical Properties

Melting point:
<-20°C
Boiling point:
65°C 0,4mm
alpha 
32 º (neat)
Density 
1.024 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.533
Flash point:
65°C/0.38mm
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
9.29±0.10(Predicted)
Water Solubility 
Soluble in water (10g/L).
Sensitive 
Air Sensitive
BRN 
2413029
InChIKey
JTDGKQNNPKXKII-SSDOTTSWSA-N
CAS DataBase Reference
22038-86-4(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C
Risk Statements 
34-22
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2735 8/PG 3
WGK Germany 
3
10-34
HazardClass 
8
PackingGroup 
III
HS Code 
29222990

MSDS

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(R)-(+)-1-(4-Methoxyphenyl)ethylamine Usage And Synthesis

Chemical Properties

Colorless liquid

Uses

(R)-(+)-1-(4-Methoxyphenyl)ethylamine use in diastereo-and enantioselective Michael addition reactions. Thiazoles has been prepared from (R)-(+)-1-(4-Methoxyphenyl)ethylamine.

Uses

(R)-(+)-4-Methoxy-α-methylbenzylamine can be used as a reactant to prepare:

  • Enantiopure stereoisomers of hemicryptophanes, which are used for the recognition of glucopyranosides.
  • Bicyclic Geissman-Waiss lactone via intramolecular ring-closure reaction of the diastereomeric mixture of sulfonium salts.
  • N-[(1R)-1-(4-Methoxyphenyl)ethyl]-N′-methylthiourea by reacting with methyl isothiocyanate.

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