N'-Nitro-L-arginine
N'-Nitro-L-arginine Basic information
- Product Name:
- N'-Nitro-L-arginine
- Synonyms:
-
- (+)-nc-nitroarginine
- H-Arg(NO2)-OH
- Nω-Nitro-L-arginine
- N5-(Nitroamidino)-L-2,5-diaminopentanoic acid
- NG-NO2-L-Arg
- L-NNA
- L-NO2ARG
- L-NOARG
- CAS:
- 2149-70-4
- MF:
- C6H13N5O4
- MW:
- 219.2
- EINECS:
- 218-418-9
- Product Categories:
-
- Arginine [Arg, R]
- Amino Acids and Derivatives
- Amino Acids Derivatives
- Amino Acids
- Nitric Oxide
- Mol File:
- 2149-70-4.mol
N'-Nitro-L-arginine Chemical Properties
- Melting point:
- 257 °C (dec.)(lit.)
- alpha
- 23.5 º (c=4, 2N HCl 24 ºC)
- Boiling point:
- 360°C (rough estimate)
- Density
- 1.4177 (rough estimate)
- refractive index
- 1.8000 (estimate)
- RTECS
- RM2982100
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMF: <50 μg/ml; DMSO: <50 μg/ml; Ethanol: <50 μg/ml; PBS pH 7.2: 1 mg/ml
- pka
- 2.49±0.24(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- Water Solubility
- Soluble to 5 mM in water
- BRN
- 1728914
- InChIKey
- MRAUNPAHJZDYCK-BYPYZUCNSA-N
- CAS DataBase Reference
- 2149-70-4(CAS DataBase Reference)
- EPA Substance Registry System
- L-Ornithine, N5-[imino(nitroamino)methyl]- (2149-70-4)
Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 22-24/25-36-26
- WGK Germany
- 3
- TSCA
- Yes
- HazardClass
- IRRITANT
- HS Code
- 29299090
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
N'-Nitro-L-arginine Usage And Synthesis
Chemical Properties
WHITE TO OFF-WHITE POWDER
Uses
Nω-Nitro-L-arginine is an inhibitor for nitric oxide synthase and is used in the study of bacterium to determine effective treatments. Used in the study of MRSA (Methicillin-Resistant Staphylococcus Aureus).
Definition
ChEBI: N(gamma)-nitro-L-arginine is an L-arginine derivative that is L-arginine in which the terminal nitrogen of the guanidyl group is replaced by a nitro group. It is a L-arginine derivative, a N-nitro compound, a member of guanidines and a non-proteinogenic L-alpha-amino acid.
Hazard
A reproductive hazard.
Biological Activity
NO synthase inhibitor.
Biochem/physiol Actions
Nω-Nitro-L-arginine/L-NNA helps to reduce the levels of cortical hyperemia and brain cGMP occurring due to hypercapnia.
Safety Profile
Experimental reproductiveeffects. When heated to decomposition it emits toxicvapors of NOx.
N'-Nitro-L-arginineSupplier
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N'-Nitro-L-arginine(2149-70-4)Related Product Information
- ARGINASE
- 6-Aminocaproic acid
- L-Arginine hydrochloride
- L(+)-Arginine
- Orotic acid
- EPA
- Oxolinic acid
- Arginine
- arginine aspirin
- NITROGEN DIOXIDE
- N-Boc-N'-nitro-L-arginine
- Z-ARG(NO2)-OH
- FMOC-ARG(NO2)-OH
- N'-Nitro-L-arginine-methyl ester hydrochloride
- N'-Nitro-D-arginine
- FMOC-N-OMEGA-NITRO-D-ARGININE
- L-Ornithine
- H-ALA-ARG(NO2)-OME HCL