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CIMIFUGIN BETA-D-GLUCOPYRANOSIDE
CIMIFUGIN BETA-D-GLUCOPYRANOSIDE Basic information
- Product Name:
- CIMIFUGIN BETA-D-GLUCOPYRANOSIDE
- Synonyms:
-
- CIMIFUGIN BETA-D-GLUCOPYRANOSIDE
- 5H-Furo[3,2-g][1]benzopyran-5-one,7-[(β-D-
- glucopyranosyloxy)methyl]-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-4-methoxy-,(2S)-
- Prim-O-glucosylcimifugin, 98%, from Cimicifuga foetida L.
- prim-O-Glucosylcimifugin
- (2S)-2-(2-hydroxypropan-2-yl)-4-methoxy-7-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-2,3-dihydrofuro[3,2-g]chromen-5-one
- Cimifugin 7-glucoside
- rim-O-glucosylcimifugin
- CAS:
- 80681-45-4
- MF:
- C22H28O11
- MW:
- 468.45
- Product Categories:
-
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Mol File:
- 80681-45-4.mol
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CIMIFUGIN BETA-D-GLUCOPYRANOSIDE Chemical Properties
- Melting point:
- 118～120℃
- Boiling point:
- 736.9±60.0 °C(Predicted)
- Density
- 1.53±0.1 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- solubility
- DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 15 mg/ml; PBS (pH 7.2): 5 mg/ml
- pka
- 12.94±0.70(Predicted)
- form
- powder to crystal
- color
- White to Light yellow
- InChIKey
- XIUVHOSBSDYXRG-BZOGYWBENA-N
- SMILES
- C12=C(C=C3O[C@H](C(C)(C)O)CC3=C1OC)OC(CO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)=CC2=O |&1:5,19,21,24,26,28,r|
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Safety Information
- Safety Statements
- 24/25
- HS Code
- 29389090
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CIMIFUGIN BETA-D-GLUCOPYRANOSIDE Usage And Synthesis
Chemical Properties
White crystalline powder, soluble in methanol, derived from Fangji, Fangfeng, Huashan Qianhu.
Uses
Prim-O-glucosylcimifugin have anti-inflammatory, immunosuppressive effects.
Definition
ChEBI: PRIM-O-GLUCOSYLCIMIFUGIN is an organic heterotricyclic compound and an oxacycle.
in vivo
Bronchoalveolar lavage fluid (BALF) is collected at 7 h after lipopolysaccharide (LPS) administration and the cytokine levels in BALF are measured by ELISA. The levels of TNF-α, IL-1β and IL-6 in BALF are increased dramatically compared with control group. However, pretreatment with Prime-O-glucosylcimifugin (2.5, 5 or 10 mg/kg) significantly down-regulates the levels of TNF-α, IL-1β and IL-6 in a dose-dependent manner (P<0.05, P<0.01)[1].
target
| COX-2 < span> | iNOS
|
IC 50
iNOS; COX-2
CIMIFUGIN BETA-D-GLUCOPYRANOSIDESupplier
Hubei Danding Pharmaceutical Technology Co., Ltd Gold
- Tel
- 17701422019
- 1559451077@qq.com
CHENGDU JINMAIRUI BIO-TECHNOLOGY CO.LTD Gold
- Tel
- 028-83133020 18280298385
- 1223808415@qq.com
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd Gold
- Tel
- 17701422015
- 3582572959@qq.com
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
- sales@BioChemBest.com
Adamas Reagent, Ltd.
- Tel
- 400-6009262 16621234537
- chenyj@titansci.com
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CIMIFUGIN BETA-D-GLUCOPYRANOSIDE(80681-45-4)Related Product Information
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- Baicalin
- Praeruptorin A
- 7,8-Dihydroxycoumarin
- Black Cohosh P.E Triterpenoid saponis 2.5% 8% HPLC
- CIMIFUGIN BETA-D-GLUCOPYRANOSIDE
- NORCIMIFUGIN(P)
- 5-O-METHYLVISAMMINOL
- 1-[2-(2-ETHOXYETHOXY)-6-HYDROXYPHENYL]ETHAN-1-ONE