DL-Homocysteine
DL-Homocysteine Basic information
- Product Name:
- DL-Homocysteine
- Synonyms:
-
- DL-Homocysteine,95%
- HOMOCYSTEINE, DL-(P)
- DL-Homocysteine,2-Amino-4-mercaptobutyric acid
- DL-HoMocystein
- (+-)-homocysteine
- Butyric acid, 2-amino-4-mercapto-, DL- (9CI)
- (2R)-2-ammonio-4-mercaptobutanoate
- dl-2-amino-4-mercaptobutyricacid
- CAS:
- 454-29-5
- MF:
- C4H9NO2S
- MW:
- 135.18
- EINECS:
- 207-222-9
- Product Categories:
-
- Amino Acids
- Amino Acids
- Mol File:
- 454-29-5.mol
DL-Homocysteine Chemical Properties
- Melting point:
- 232-233 °C(lit.)
- Boiling point:
- 299.7±35.0 °C(Predicted)
- Density
- 1.149 (estimate)
- refractive index
- 1.5480 (estimate)
- Flash point:
- >230 °F
- storage temp.
- -20°C
- solubility
- H2O: soluble
- pka
- 2.22, 8.87, 10.86(at 25℃)
- form
- solid
- color
- White to Off-White
- optical activity
- [α]/D 0±1°, c = 1 in H2O
- Merck
- 14,4734
- BRN
- 1721683
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- InChIKey
- FFFHZYDWPBMWHY-UHFFFAOYSA-N
- LogP
- 0.220 (est)
- CAS DataBase Reference
- 454-29-5(CAS DataBase Reference)
MSDS
- Language:English Provider:SigmaAldrich
DL-Homocysteine Usage And Synthesis
Chemical Properties
white powder
Uses
DL-Homocysteine has been used to induce hyperhomocysteinemia in Sprague–Dawley rats. It has also been used to study the effects of hyperhomocysteinemia on atherosclerosis in apolipoprotein E-deficient mice.
Definition
ChEBI: A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain.
Biochem/physiol Actions
Homocysteine is a sulfhydryl-containing amino acid, synthesized from methionine. It is a non-essential, non-proteinogenic amino acid. It is an important determinant of the methylation cycle and is present in the plasma in four forms. An abnormally high level of homocysteine leads to hyperhomocysteinemia and also promotes atherosclerosis.
Purification Methods
Purify it as for the L-isomer. [Allen & Steinmann J Am Chem Soc 74 3932 1952, and references for the L-isomer above, Beilstein 4 IV 3189.]
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DL-Homocysteine(454-29-5)Related Product Information
- 4-Aminobutyric acid
- 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE
- Mercaptoacetic acid
- 2-Ethylhexyl mercaptoacetate
- DL-Cystine
- L-Cysteine
- L-HOMOCYSTEINE
- 6-Aminocaproic acid
- Glycine
- DL-Cysteine
- N-Acetyl-L-cysteine
- Ethyl L-methionate hydrochloride
- 2-Mercaptoethanol
- L-CYSTEINE HCL ANHYDROUS
- L-Methionine methyl ester hydrochloride
- N-Acetyl-DL-methionine
- L-ETHIONINE
- Z-PRO-MET-OH