Diazolidinyl Urea Chemical Properties

Boiling point:

421.04°C (rough estimate)

Density 

1.4734 (rough estimate)

vapor pressure 

0Pa at 20℃

refractive index 

1.6590 (estimate)

storage temp. 

2-8°C

solubility 

Water (Slightly)

form 

Solid

pka

11.22±0.46(Predicted)

color 

White to Off-White

Water Solubility 

1000g/L at 20℃

Merck 

14,3000

Stability:

Stable. Incompatible with strong oxidizing agents.

InChIKey

SOROIESOUPGGFO-UHFFFAOYSA-N

LogP

0.9 at 20℃

CAS DataBase Reference

78491-02-8(CAS DataBase Reference)

EPA Substance Registry System

Diazolidinylurea (78491-02-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

43

Safety Statements 

36/37

WGK Germany 

2

RTECS 

YS2717000

HS Code 

29339900

Toxicity

LD50 orally in rats: 2.57 g/kg; dermally in rabbits: >2.0 g/kg (Berke, Rosen)

MSDS

• Language:English Provider:SigmaAldrich

Diazolidinyl Urea Usage And Synthesis

Description

Diazolidinyl urea was first introduced in 1982 (Sutton Labs, Chatham, New Jersey). It is a colorless, odorless, stable, and water-soluble preservative. It is reported to have a wider antimicrobial spectrum than imidazolidinyl urea, which is structurally related. It is effective against gram-negative and gram-positive bacteria, molds, and yeast but has limited activity against fungi. Diazolidinyl urea, a formaldehyde re1easer, is mainly contained in cosmetics and toiletries, and can be found in barrier creams.

Chemical Properties

white powder

Uses

diazolidinyl urea is an antiseptic and deodorizer. It is also a broadspectrum preservative against bacteria and fungi. generally, it is used in concentrations of 0.03 to 0.3 percent. It has been found that diazolidinyl urea is a stronger sensitizer than imidazolidinyl urea for people sensitive or allergic to formaldehyde.

Uses

2,5-Diazolidinylurea is a preservative used in cosmetic creams, lotions, shampoos, hair gels, etc.

Definition

ChEBI: Diazolidinylurea is an imidazolidine-2,4-dione.

Flammability and Explosibility

Non flammable

Contact allergens

Diazolidinyl urea, a formaldehyde releaser, is contained mainly in cosmetics and toiletries and can be found in barrier creams.

Safety

The Cosmetic Ingredient Review Expert Panel evaluated the safety of diazolidinyl urea and found that the ingredient is safe for current uses and concentrations, and it has low eye irritation potential. However, it has not been found to be sensitive to the skin or produce phototoxic effects.  It’s use is restricted to maximum concentrations of 0.5%. This limit in concentration is mostly due to mild irritation that can occur on the skin in concentrations greater that this maximum. 

Diazolidinyl Urea(78491-02-8)Related Product Information

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• Tris(hydroxymethyl)nitromethane
• Biuret
• Mesotrione
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• CHLORPROPAMIDE
• Sodium dodecyl sulfate
• 2,2'-Azodi(2-methylbutyronitrile)
• Diazomethane
• BIUREA
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• 2,2-Bis(hydroxymethyl)propionic acid
• Imidazolidinyl urea
• N-OCTADECYLTRICHLOROSILANE
• Myristyl chloroformate
• Diethyl azodicarboxylate
• 2,2'-Azobis(2-methylpropionitrile)