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DL-Histidine

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DL-Histidine Basic information

Product Name:
DL-Histidine
Synonyms:
  • 1H-Imidazole-4-alanine
  • D-Histidine/L-histidine,(1:1)
  • rac-(R*)-2-Amino-3-(4-imidazolyl)propionic acid
  • DL-Histidine,98%
  • DL-Histdine
  • H-DL-His-OH (DL-Histidine
  • DL-Histidine 0
  • DL-Histidine 
CAS:
4998-57-6
MF:
C6H9N3O2
MW:
155.15
EINECS:
225-660-9
Product Categories:
  • alpha-Amino Acids
  • Amino Acids
  • Biochemistry
  • Amino Acids
Mol File:
4998-57-6.mol
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DL-Histidine Chemical Properties

Melting point:
273 °C (dec.)(lit.)
Boiling point:
278.95°C (rough estimate)
Density 
1.3092 (rough estimate)
refractive index 
1.6500 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
0.5 M HCl: soluble
pka
1.8(at 25℃)
Merck 
14,4720
BRN 
7800
CAS DataBase Reference
4998-57-6(CAS DataBase Reference)
EPA Substance Registry System
Histidine (4998-57-6)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
22-24/25-36/37-26
WGK Germany 
3
HS Code 
29339900

MSDS

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DL-Histidine Usage And Synthesis

Chemical Properties

white to slightly yellow crystalline powder

Uses

histidine is a skin-conditioning amino acid.

Uses

DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).

Definition

ChEBI: An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.

Synthesis Reference(s)

Journal of the American Chemical Society, 67, p. 502, 1945 DOI: 10.1021/ja01219a513
Chemical and Pharmaceutical Bulletin, 35, p. 3447, 1987

Biochem/physiol Actions

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

DL-Histidine Preparation Products And Raw materials

Raw materials

DL-HistidineSupplier

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