1-METHYL-2-INDOLINONE Chemical Properties

Melting point:

85-88 °C(lit.)

Boiling point:

110-120 °C(Press: 1 Torr)

Density 

1.167±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

solid

pka

0.40±0.20(Predicted)

color 

White to pink

CAS DataBase Reference

61-70-1(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

NM2208800

HS Code 

2933790090

1-METHYL-2-INDOLINONE Usage And Synthesis

Chemical Properties

Light-Yellow Solid

Uses

1-Methyl-2-indolone is a reactant for preparation of fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching, irreversible Nek2 Kinase Inhibitors and anticancer agents.

Uses

Reactant for preparation of:

• Fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching
• Irreversible Nek2 Kinase Inhibitors
• Anticancer agents
• Antimalarial agents
• Antitimor agents
• Germination stimulants in plants
• Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1)
• Retinoic acid analogs
• Potential anti-multiple sclerosis agents
• Inhibitors of human immunodeficiency virus type 1 (HIV-1) integrase

Uses

1-Methyl-2-oxindole is used in the prevention and therapy of atherosclerotic degradation of arterial walls.

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 435, 1985 DOI: 10.1021/ja00288a027
Journal of Heterocyclic Chemistry, 23, p. 1163, 1986 DOI: 10.1002/jhet.5570230439

1-METHYL-2-INDOLINONE(61-70-1)Related Product Information

• 1-Methylindole
• Amedalin
• N-METHYLISATIN-3-THIOSEMICARBAZONE
• N-METHYLISATIN
• 1-PHENYLISATIN
• 1-(Hydroxymethyl)indoline-2,3-dione
• 1-METHYL-2-INDOLINONE
• Lercanidipine
• Oxindole
• Nifedipine
• 4-(3-Nitrophenyl)pyridine
• AKOS BBS-00001025
• 1-METHYL-5-NITRO-ISATIN
• 1-(4-CHLORO-BENZYL)-1H-INDOLE-2,3-DIONE
• (2,3-DIOXO-2,3-DIHYDRO-INDOL-1-YL)-ACETIC ACID
• 1-BENZYL-3-(BROMOMETHYL)-3-PHENYLINDOLIN-2-ONE
• TIMTEC-BB SBB006823
• 1-(MORPHOLIN-4-YLMETHYL)-1H-INDOLE-2,3-DIONE