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4-NITROPHENYL-BETA-D-GLUCURONIDE

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4-NITROPHENYL-BETA-D-GLUCURONIDE Basic information

Product Name:
4-NITROPHENYL-BETA-D-GLUCURONIDE
Synonyms:
  • 4-NITROPHENYL-BETA-D-GLUCOPYRANOSIDURONIC ACID
  • (4-NITRO)PHENYL-BETA-D-GLUCORONIDE
  • 4-NITROPHENYL-BETA-D-GLUCURONIC ACID
  • 4-NITROPHENYL-BETA-D-GLUCURONIDE
  • P-NITROPHENYL BETA-D-GLUCOPYRANOSIDURONIC ACID
  • P-NITROPHENYL BETA-D-GLUCURONIDE
  • PNP-BETA-D-GLCA
  • PNP BETA-D-GLUCURONIDE
CAS:
10344-94-2
MF:
C12H13NO9
MW:
315.23
EINECS:
233-753-0
Product Categories:
  • Biochemistry
  • Glucose
  • Substrates
  • Glycosides
  • Sugars
  • substrate
  • Carbohydrates & Derivatives
  • Glucuronides
Mol File:
10344-94-2.mol
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4-NITROPHENYL-BETA-D-GLUCURONIDE Chemical Properties

Melting point:
93°C
Boiling point:
644.4±55.0 °C(Predicted)
Density 
1.731±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
H2O: 0.1 g/mL, clear, faintly yellow
form 
Liquid
pka
2.69±0.70(Predicted)
color 
Clear colorless to light yellow
optical activity
[α]20/D 102±3°, c = 1% in ethanol
Water Solubility 
Water : 250 mg/mL (793.07 mM; Need ultrasonic)
BRN 
1438576
InChIKey
QSUILVWOWLUOEU-GOVZDWNOSA-N
CAS DataBase Reference
10344-94-2(CAS DataBase Reference)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
10-21
HS Code 
29329990

MSDS

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4-NITROPHENYL-BETA-D-GLUCURONIDE Usage And Synthesis

Chemical Properties

Crystalline Solid

Uses

4-Nitrophenyl β-D-glucuronide has been used for determining the β-glucuronidase activity in urine samples, β-glucuronidase activity of bacteria in caecum content digesta and bovine liver. It has also been used to study the inhibitory effect of Phyllanthus amarus extracts on β-glucuronidase.

Uses

4-Nitrophenyl β-D-glucuronide has been used as substrate in acetate buffer to measure β-glucuronidase.

Definition

ChEBI: A beta-D-glucosiduronic acid having a 4-nitrophenyl substituent at the anomeric position.

General Description

Chromogenic substrate for β-glucuronidase (Km = ~0.22 mM).

4-NITROPHENYL-BETA-D-GLUCURONIDESupplier

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