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ilexsaponin B2

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ilexsaponin B2 Basic information

Product Name:
ilexsaponin B2
Synonyms:
  • ilexsaponin B2
  • 2)-beta-D-xylopyranosyl)oxy]-19-hydroxy-urs-12-en-28-oic acid
  • (3beta,20beta)-3-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1-2)-O-beta-D-glucopyranosyl-(1-2)-beta-D-xylopyranosyl)oxy]-19-hydroxy-urs-12-en-28-oic acid
  • product/154922
  • Urs-12-en-28-oic acid, 3-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-β-D-xylopyranosyl)oxy]-19-hydroxy-, (3β,20β)-
  • Xanthone Impurity 14-d7
CAS:
108906-69-0
MF:
C47H76O17
MW:
913.11
Mol File:
108906-69-0.mol
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ilexsaponin B2 Chemical Properties

Boiling point:
994.7±65.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
pka
4.47±0.70(Predicted)
InChIKey
KWHRIYSRPSARCX-LCRMJRRRNA-N
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ilexsaponin B2 Usage And Synthesis

Uses

Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively[1].

IC 50

PDE5: 48.8 μM (IC50); PDEI: 477.5 μM (IC50)

References

[1] Zichen Liu, et al. Rapid Screening of Potential Phosphodiesterase Inhibitors From the Roots of Ilex pubescens Hook. Et Arn. Using a Combination of Ultrafiltration and LC-MS. Evid Based Complement Alternat Med. 2017;2017:2749643. DOI:10.1155/2017/2749643

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