3,5-Dimethoxybenzylamine Chemical Properties

Melting point:

35-37 °C (lit.)

Boiling point:

94-96 °C/0.1 mmHg (lit.)

Density 

1.106 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.542(lit.)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

pka

9.01±0.10(Predicted)

form 

powder to lump

color 

White to Light yellow

Water Solubility 

Slightly soluble in water.

λmax

281nm(EtOH)(lit.)

InChI

1S/C9H13NO2/c1-11-8-3-7(6-10)4-9(5-8)12-2/h3-5H,6,10H2,1-2H3

InChIKey

YGZJTYCCONJJGZ-UHFFFAOYSA-N

SMILES

COc1cc(CN)cc(OC)c1

CAS DataBase Reference

34967-24-3(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39

RIDADR 

3259

WGK Germany 

3

HazardClass 

IRRITANT

HazardClass 

8

PackingGroup 

III

HS Code 

29222990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

MSDS

• Language:English Provider:SigmaAldrich

3,5-Dimethoxybenzylamine Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

3,5-Dimethoxybenzylamine was used in the preparation of trisammonium tris(hexafluoro phosphate) salt. It was also used in the synthesis of well defined, homogeneous [n]rotaxanes (n up to 11) by a template-directed thermodynamic clipping approach.

Synthesis Reference(s)

Tetrahedron Letters, 35, p. 6207, 1994 DOI: 10.1016/S0040-4039(00)73392-2

General Description

3,5-Dimethoxybenzylamine was prepared by LiAlH₄-reduction of 3,5-dimethoxybenzaldoxime.

Synthesis

7 mmol of 3,5-dimethoxybenzaldehyde, 70 mL of methanol solution of ammonia at a concentration of 2 mol/L, and 140 mg of murrayne-encapsulated nickel-nickel oxide catalyst were mixed and added to an autoclave reactor, and then hydrogen was passed in, and the hydrogen pressure of the system was controlled to be 2 MPa, the stirring rate was 800 rpm, and the reaction was carried out at 90 ??C for 4 h. 3,5-dimethoxybenzylamine was obtained (the yield was 95%).

3,5-Dimethoxybenzylamine(34967-24-3)Related Product Information

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